hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02920
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RTF2 | Replication termination factor 2 (RTF2) (Replication termination factor 2 domain-containing protein 1) | UniProt NCBI |
| BBOX1 | Gamma-butyrobetaine dioxygenase (EC 1.14.11.1) (Gamma-butyrobetaine hydroxylase) (Gamma-BBH) (Gamma-butyrobetaine,2-oxoglutarate dioxygenase) | UniProt NCBI |
| AZI2 | 5-azacytidine-induced protein 2 (NF-kappa-B-activating kinase-associated protein 1) (Nak-associated protein 1) (TILP) | UniProt NCBI |
| CASP2 | Caspase-2 (CASP-2) (EC 3.4.22.55) (Neural precursor cell expressed developmentally down-regulated protein 2) (NEDD-2) (Protease ICH-1) [Cleaved into: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12] | UniProt NCBI |
| BANF1 | Barrier-to-autointegration factor (Breakpoint cluster region protein 1) [Cleaved into: Barrier-to-autointegration factor, N-terminally processed] | UniProt NCBI |
| TANK | TRAF family member-associated NF-kappa-B activator (TRAF-interacting protein) (I-TRAF) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:5212 | 0.000234668084372 | 0.333333333333 | AZI2 TANK | Kinase maturation complex 2 |
| WP:WP3865 | 0.00792327646772 | 0.333333333333 | AZI2 TANK | Novel intracellular components of RIG-I-like receptor (RLR) pathway |
| KEGG:04622 | 0.0124835568261 | 0.333333333333 | AZI2 TANK | RIG-I-like receptor signaling pathway |
| CORUM:1989 | 0.0249904952816 | 0.166666666667 | BANF1 | BANF1 homodimer protein |
| CORUM:6148 | 0.0249904952816 | 0.166666666667 | BANF1 | BAFL-BAF complex |
| CORUM:129 | 0.0499726005494 | 0.166666666667 | CASP2 | PIDDsome complex |
| CORUM:6147 | 0.0499726005494 | 0.166666666667 | BANF1 | BAFL-BAF-LAP2beta complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| BBOX1 | CASP2 | 0.983 | 0.899 | bioplex (BBOX1) bioplex_WMM |
| BBOX1 | RTF2 | 0.622 | 0.677 | bioplex (BBOX1) bioplex_WMM |
| BBOX1 | AZI2 | 0.598 | 0.668 | bioplex (BBOX1) bioplex_WMM |
| BANF1 | RTF2 | 0.031 | 0.24 | bioplex_WMM fraction |
| BBOX1 | TANK | 0.024 | 0.214 | bioplex (BBOX1) bioplex_WMM |
| TANK | AZI2 | 0.009 | 0.097 | bioplex_WMM WMM_only |
| CASP2 | AZI2 | 0.009 | 0.096 | bioplex_WMM WMM_only |
| RTF2 | AZI2 | 0.009 | 0.096 | bioplex_WMM WMM_only |
| CASP2 | TANK | 0.008 | 0.089 | bioplex_WMM WMM_only |
| RTF2 | TANK | 0.008 | 0.028 | bioplex_WMM WMM_only |
| CASP2 | RTF2 | 0.008 | 0.016 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_02920 has an average edge precision of 0.284 which is ranked 4829 out of all 6965 complexes.
Related Complexes