hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02934
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| GIGYF1 | GRB10-interacting GYF protein 1 (PERQ amino acid-rich with GYF domain-containing protein 1) | UniProt NCBI |
| GIGYF2 | GRB10-interacting GYF protein 2 (PERQ amino acid-rich with GYF domain-containing protein 2) (Trinucleotide repeat-containing gene 15 protein) | UniProt NCBI |
| CHD7 | Chromodomain-helicase-DNA-binding protein 7 (CHD-7) (EC 3.6.4.12) (ATP-dependent helicase CHD7) | UniProt NCBI |
| EIF4E2 | Eukaryotic translation initiation factor 4E type 2 (eIF-4E type 2) (eIF4E type 2) (Eukaryotic translation initiation factor 4E homologous protein) (Eukaryotic translation initiation factor 4E-like 3) (eIF4E-like protein 4E-LP) (mRNA cap-binding protein 4EHP) (h4EHP) (mRNA cap-binding protein type 3) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0004409 | 0.0167876216717 | 0.5 | CHD7 GIGYF2 | Hyposmia |
| MIRNA:hsa-miR-3692-5p | 0.0335416748159 | 0.5 | GIGYF1 CHD7 | hsa-miR-3692-5p |
| HP:0004408 | 0.0413775694569 | 0.5 | CHD7 GIGYF2 | Abnormality of the sense of smell |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| GIGYF1 | EIF4E2 | 0.992 | 0.912 | bioplex (EIF4E2) bioplex_WMM boldt boldt_WMM |
| EIF4E2 | GIGYF2 | 0.954 | 0.861 | bioplex (EIF4E2) bioplex_WMM boldt gupta_WMM boldt_WMM |
| GIGYF2 | CHD7 | 0.023 | 0.211 | gupta_WMM fraction |
| GIGYF1 | GIGYF2 | 0.008 | 0.088 | bioplex_WMM boldt gupta_WMM boldt_WMM |
| EIF4E2 | CHD7 | 0.007 | 0.004 | youn_WMM WMM_only |
Images
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Complex HuMAP2_02934 has an average edge precision of 0.415 which is ranked 3151 out of all 6965 complexes.
Related Complexes