hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02958
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SLC7A1 | High affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor homolog) (Ecotropic retrovirus receptor homolog) (Solute carrier family 7 member 1) (System Y+ basic amino acid transporter) | UniProt NCBI |
| SIGMAR1 | Sigma non-opioid intracellular receptor 1 (Aging-associated gene 8 protein) (SR31747-binding protein) (SR-BP) (Sigma 1-type opioid receptor) (SIG-1R) (Sigma1-receptor) (Sigma1R) (hSigmaR1) | UniProt NCBI |
| BCL2L13 | Bcl-2-like protein 13 (Bcl2-L-13) (Bcl-rambo) (Protein Mil1) | UniProt NCBI |
| ELOVL5 | Elongation of very long chain fatty acids protein 5 (EC 2.3.1.199) (3-keto acyl-CoA synthase ELOVL5) (ELOVL fatty acid elongase 5) (ELOVL FA elongase 5) (Fatty acid elongase 1) (hELO1) (Very long chain 3-ketoacyl-CoA synthase 5) (Very long chain 3-oxoacyl-CoA synthase 5) | UniProt NCBI |
| TMEM11 | Transmembrane protein 11, mitochondrial (Protein PM1) (Protein PMI) | UniProt NCBI |
| AGPAT4 | 1-acyl-sn-glycerol-3-phosphate acyltransferase delta (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 4) (1-AGP acyltransferase 4) (1-AGPAT 4) (Lysophosphatidic acid acyltransferase delta) (LPAAT-delta) | UniProt NCBI |
| SURF4 | Surfeit locus protein 4 | UniProt NCBI |
| TMEM120B | Transmembrane protein 120B | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| MIRNA:hsa-miR-6850-3p | 0.0283730375767 | 0.25 | TMEM120B AGPAT4 | hsa-miR-6850-3p |
| CORUM:6563 | 0.0497224828424 | 0.125 | SURF4 | SPG33-SURF4 complex |
| CORUM:6735 | 0.0497224828424 | 0.125 | SIGMAR1 | SIGMAR1-KCNH2 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| AGPAT4 | SLC7A1 | 0.081 | 0.349 | bioplex (SLC7A1) bioplex_WMM boldt boldt_WMM |
| SLC7A1 | SIGMAR1 | 0.044 | 0.274 | bioplex (SLC7A1) bioplex_WMM boldt gupta_WMM boldt_WMM |
| SURF4 | SLC7A1 | 0.037 | 0.265 | bioplex (SLC7A1) bioplex_WMM boldt gupta_WMM boldt_WMM |
| SLC7A1 | TMEM120B | 0.032 | 0.241 | bioplex (SLC7A1) bioplex_WMM boldt gupta_WMM boldt_WMM |
| BCL2L13 | SLC7A1 | 0.025 | 0.212 | bioplex (SLC7A1) bioplex_WMM |
| SLC7A1 | TMEM11 | 0.025 | 0.211 | bioplex (SLC7A1) bioplex_WMM boldt boldt_WMM |
| ELOVL5 | SLC7A1 | 0.023 | 0.207 | bioplex (SLC7A1) bioplex_WMM boldt gupta_WMM boldt_WMM |
| AGPAT4 | TMEM120B | 0.012 | 0.146 | bioplex_WMM boldt boldt_WMM |
| SURF4 | SIGMAR1 | 0.01 | 0.134 | bioplex_WMM boldt gupta_WMM boldt_WMM |
| TMEM120B | SIGMAR1 | 0.01 | 0.105 | bioplex_WMM boldt gupta_WMM boldt_WMM |
| ELOVL5 | TMEM120B | 0.008 | 0.08 | bioplex_WMM gupta_WMM WMM_only |
| AGPAT4 | SIGMAR1 | 0.008 | 0.066 | bioplex_WMM boldt boldt_WMM |
| AGPAT4 | SURF4 | 0.008 | 0.044 | bioplex_WMM boldt boldt_WMM |
| ELOVL5 | BCL2L13 | 0.008 | 0.04 | bioplex_WMM WMM_only |
| ELOVL5 | SIGMAR1 | 0.008 | 0.037 | bioplex_WMM boldt gupta_WMM boldt_WMM |
| SURF4 | TMEM120B | 0.008 | 0.025 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| BCL2L13 | TMEM120B | 0.007 | 0.009 | bioplex_WMM WMM_only |
| BCL2L13 | TMEM11 | 0.007 | 0.006 | bioplex_WMM WMM_only |
| ELOVL5 | AGPAT4 | 0.007 | 0.011 | bioplex_WMM boldt boldt_WMM |
| ELOVL5 | TMEM11 | 0.007 | 0.008 | bioplex_WMM WMM_only |
| ELOVL5 | SURF4 | 0.007 | 0.004 | bioplex_WMM boldt gupta_WMM boldt_WMM |
| AGPAT4 | BCL2L13 | 0.007 | 0.002 | bioplex_WMM WMM_only |
| BCL2L13 | SIGMAR1 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| TMEM120B | TMEM11 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| BCL2L13 | SURF4 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| SIGMAR1 | TMEM11 | 0.006 | 0.003 | bioplex_WMM boldt boldt_WMM |
| AGPAT4 | TMEM11 | 0.006 | 0.006 | bioplex_WMM boldt boldt_WMM |
| SURF4 | TMEM11 | 0.005 | 0.011 | bioplex_WMM boldt youn_WMM boldt_WMM |
Images
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Complex HuMAP2_02958 has an average edge precision of 0.09 which is ranked 6951 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SLC7A1 | HuMAP2_02958 HuMAP2_03820 HuMAP2_06709 |
| SIGMAR1 | HuMAP2_02958 HuMAP2_05696 HuMAP2_06709 |
| BCL2L13 | HuMAP2_02958 |
| ELOVL5 | HuMAP2_00516 HuMAP2_02958 |
| TMEM11 | HuMAP2_02958 |
| AGPAT4 | HuMAP2_02958 HuMAP2_06709 |
| SURF4 | HuMAP2_02958 |
| TMEM120B | HuMAP2_02958 HuMAP2_04927 |