hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02966
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| VPS45 | Vacuolar protein sorting-associated protein 45 (h-VPS45) (hlVps45) | UniProt NCBI |
| EHD3 | EH domain-containing protein 3 (PAST homolog 3) | UniProt NCBI |
| RBSN | Rabenosyn-5 (110 kDa protein) (FYVE finger-containing Rab5 effector protein rabenosyn-5) (RAB effector RBSN) (Zinc finger FYVE domain-containing protein 20) | UniProt NCBI |
| STX16 | Syntaxin-16 (Syn16) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04144 | 0.000539397470166 | 0.75 | VPS45 RBSN EHD3 | Endocytosis |
| REAC:R-HSA-983231 | 0.000880763368668 | 0.75 | VPS45 RBSN EHD3 | Factors involved in megakaryocyte development and platelet production |
| REAC:R-HSA-6811438 | 0.00947680746611 | 0.5 | VPS45 STX16 | Intra-Golgi traffic |
| GO:0042147 | 0.0308728000114 | 0.75 | EHD3 RBSN STX16 | retrograde transport, endosome to Golgi |
| REAC:R-HSA-109582 | 0.033540764945 | 0.75 | VPS45 RBSN EHD3 | Hemostasis |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| VPS45 | RBSN | 0.987 | 0.901 | bioplex (RBSN,VPS45) bioplex_WMM youn_WMM Malo gupta_WMM fraction boldt_WMM |
| VPS45 | STX16 | 0.703 | 0.723 | bioplex (VPS45) bioplex_WMM youn_WMM gupta_WMM boldt_WMM |
| RBSN | EHD3 | 0.191 | 0.444 | bioplex (RBSN) bioplex_WMM |
| STX16 | RBSN | 0.008 | 0.066 | bioplex_WMM youn_WMM WMM_only |
| VPS45 | EHD3 | 0.008 | 0.066 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_02966 has an average edge precision of 0.44 which is ranked 2937 out of all 6965 complexes.
Related Complexes