hu.MAP 2.0: Complex View

Human Protein Complex Map

Complex: HuMAP2_02967

Confidence: Medium

Genename	Protein Name	Links
WNK2	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Antigen NY-CO-43) (Protein kinase lysine-deficient 2) (Protein kinase with no lysine 2) (Serologically defined colon cancer antigen 43)	UniProt NCBI
WNK1	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Erythrocyte 65 kDa protein) (p65) (Kinase deficient protein) (Protein kinase lysine-deficient 1) (Protein kinase with no lysine 1) (hWNK1)	UniProt NCBI
SCYL2	SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa)	UniProt NCBI
SPATA1	Spermatogenesis-associated protein 1 (Sperm-specific protein SP-2)	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
MIRNA:hsa-miR-134-3p	0.0291936286934	0.5	WNK1 WNK2	hsa-miR-134-3p
MIRNA:hsa-miR-7114-5p	0.0381896870696	0.5	WNK1 WNK2	hsa-miR-7114-5p
REAC:R-HSA-2672351	0.0408500448467	0.5	WNK1 WNK2	Stimuli-sensing channels
CORUM:1121	0.0499140284799	0.25	WNK1	WNK1-OSR1 complex
CORUM:1123	0.0499140284799	0.25	WNK1	WNK1-SPAK complex

Protein 1	Protein 2	Score	Precision	Evidence
SPATA1	SCYL2	0.934	0.849	bioplex (SPATA1) bioplex_WMM
SPATA1	WNK2	0.067	0.35	bioplex (SPATA1) bioplex_WMM
SPATA1	WNK1	0.066	0.349	bioplex (SPATA1) bioplex_WMM
WNK1	WNK2	0.009	0.107	bioplex_WMM youn_WMM WMM_only boldt_WMM
SCYL2	WNK1	0.009	0.096	hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only
SCYL2	WNK2	0.008	0.092	bioplex_WMM youn_WMM WMM_only

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ComplexPrecisionDistribution

Complex HuMAP2_02967 has an average edge precision of 0.307 which is ranked 4482 out of all 6965 complexes.

Related Complexes

Genename	Complexes
WNK2	HuMAP2_00250 HuMAP2_01207 HuMAP2_02967 HuMAP2_05990
WNK1	HuMAP2_00127 HuMAP2_02179 HuMAP2_02967 HuMAP2_03839
SCYL2	HuMAP2_00039 HuMAP2_01207 HuMAP2_02967
SPATA1	HuMAP2_00039 HuMAP2_01207 HuMAP2_02967