hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02990
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MICAL2 | [F-actin]-monooxygenase MICAL2 (EC 1.14.13.225) (Molecule interacting with CasL protein 2) (MICAL-2) | UniProt NCBI |
| SGSM2 | Small G protein signaling modulator 2 (RUN and TBC1 domain-containing protein 1) | UniProt NCBI |
| PTPRN | Receptor-type tyrosine-protein phosphatase-like N (R-PTP-N) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3) (PTP IA-2) [Cleaved into: ICA512-N-terminal fragment (ICA512-NTF); ICA512-transmembrane fragment (ICA512-TMF); ICA512-cleaved cytosolic fragment (ICA512-CCF)] | UniProt NCBI |
| PLA2G7 | Platelet-activating factor acetylhydrolase (PAF acetylhydrolase) (EC 3.1.1.47) (1-alkyl-2-acetylglycerophosphocholine esterase) (2-acetyl-1-alkylglycerophosphocholine esterase) (Group-VIIA phospholipase A2) (gVIIA-PLA2) (LDL-associated phospholipase A2) (LDL-PLA(2)) (PAF 2-acylhydrolase) | UniProt NCBI |
| PTPRN2 | Receptor-type tyrosine-protein phosphatase N2 (R-PTP-N2) (EC 3.1.3.-) (EC 3.1.3.48) (Islet cell autoantigen-related protein) (IAR) (ICAAR) (Phogrin) [Cleaved into: IA-2beta60] | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04940 | 0.00173687115815 | 0.4 | PTPRN2 PTPRN | Type I diabetes mellitus |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PTPRN2 | PTPRN | 0.99 | 0.909 | bioplex (PTPRN) bioplex_WMM |
| PLA2G7 | PTPRN | 0.5 | 0.621 | bioplex (PLA2G7) bioplex_WMM |
| PTPRN | MICAL2 | 0.216 | 0.464 | bioplex (PTPRN) bioplex_WMM |
| PTPRN | SGSM2 | 0.07 | 0.348 | bioplex (PTPRN) bioplex_WMM |
| PTPRN2 | SGSM2 | 0.008 | 0.091 | bioplex_WMM WMM_only |
| PTPRN2 | MICAL2 | 0.008 | 0.087 | bioplex_WMM WMM_only |
| MICAL2 | SGSM2 | 0.008 | 0.067 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_02990 has an average edge precision of 0.37 which is ranked 3646 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MICAL2 | HuMAP2_02990 |
| SGSM2 | HuMAP2_02990 HuMAP2_06724 |
| PTPRN | HuMAP2_01242 HuMAP2_02840 HuMAP2_02990 |
| PLA2G7 | HuMAP2_01242 HuMAP2_02990 |
| PTPRN2 | HuMAP2_01242 HuMAP2_02840 HuMAP2_02990 |