hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_02998
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RTN2 | Reticulon-2 (Neuroendocrine-specific protein-like 1) (NSP-like protein 1) (Neuroendocrine-specific protein-like I) (NSP-like protein I) (NSPLI) | UniProt NCBI |
| RTN1 | Reticulon-1 (Neuroendocrine-specific protein) | UniProt NCBI |
| SPRY2 | Protein sprouty homolog 2 (Spry-2) | UniProt NCBI |
| PLSCR1 | Phospholipid scramblase 1 (PL scramblase 1) (Ca(2+)-dependent phospholipid scramblase 1) (Erythrocyte phospholipid scramblase) (MmTRA1b) | UniProt NCBI |
| DYRK2 | Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP437 | 0.0415833403121 | 0.4 | SPRY2 PLSCR1 | EGF/EGFR Signaling Pathway |
| MIRNA:hsa-miR-5701 | 0.0435496282017 | 0.4 | DYRK2 PLSCR1 | hsa-miR-5701 |
| CORUM:6615 | 0.0499494897235 | 0.2 | RTN2 | SPG4-SPG12 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RTN1 | DYRK2 | 0.511 | 0.63 | bioplex (RTN1) bioplex_WMM |
| RTN2 | RTN1 | 0.047 | 0.29 | bioplex (RTN1) bioplex_WMM |
| PLSCR1 | RTN1 | 0.023 | 0.207 | bioplex (RTN1) bioplex_WMM |
| SPRY2 | PLSCR1 | 0.021 | 0.185 | bioplex (SPRY2) bioplex_WMM |
| RTN2 | DYRK2 | 0.008 | 0.037 | bioplex_WMM WMM_only |
| PLSCR1 | DYRK2 | 0.008 | 0.028 | bioplex_WMM WMM_only |
| PLSCR1 | RTN2 | 0.007 | 0.002 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_02998 has an average edge precision of 0.197 which is ranked 6220 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RTN2 | HuMAP2_02998 HuMAP2_05832 HuMAP2_06445 HuMAP2_06879 |
| RTN1 | HuMAP2_02998 HuMAP2_05839 HuMAP2_06879 |
| SPRY2 | HuMAP2_00077 HuMAP2_00271 HuMAP2_02998 HuMAP2_03171 HuMAP2_04240 |
| PLSCR1 | HuMAP2_00077 HuMAP2_02998 HuMAP2_03171 HuMAP2_03415 HuMAP2_04240 HuMAP2_05251 |
| DYRK2 | HuMAP2_02998 HuMAP2_05839 HuMAP2_06879 |