hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03011
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DYRK1A | Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB) | UniProt NCBI |
| SIPA1L1 | Signal-induced proliferation-associated 1-like protein 1 (SIPA1-like protein 1) (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6-targeted protein 1) | UniProt NCBI |
| LZTS2 | Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1) | UniProt NCBI |
| LZTS1 | Leucine zipper putative tumor suppressor 1 (F37/esophageal cancer-related gene-coding leucine-zipper motif) (Fez1) | UniProt NCBI |
| SIPA1L2 | Signal-induced proliferation-associated 1-like protein 2 (SIPA1-like protein 2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:044010_22 | 0.0218632359699 | 1.0 | LZTS2 LZTS1 DYRK1A SIPA1L2 SIPA1L1 | skin 2; epidermal cells[Approved,Medium] |
| HPA:014020_22 | 0.023496754377 | 1.0 | LZTS2 LZTS1 DYRK1A SIPA1L2 SIPA1L1 | endometrium 2; glandular cells[Approved,Medium] |
| HPA:011030_21 | 0.0361693500827 | 1.0 | LZTS2 LZTS1 DYRK1A SIPA1L2 SIPA1L1 | colon; peripheral nerve/ganglion[Approved,Low] |
| HPA:009020_21 | 0.0411014158404 | 1.0 | LZTS2 LZTS1 DYRK1A SIPA1L2 SIPA1L1 | cervix, uterine; squamous epithelial cells[Approved,Low] |
| HPA:046010_21 | 0.046793425152 | 1.0 | LZTS2 LZTS1 DYRK1A SIPA1L2 SIPA1L1 | smooth muscle; smooth muscle cells[Approved,Low] |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SIPA1L2 | LZTS2 | 0.999 | 0.948 | youn (LZTS2) bioplex (LZTS2) bioplex_WMM youn_WMM gupta_WMM |
| LZTS2 | LZTS1 | 0.989 | 0.902 | youn (LZTS2) bioplex (LZTS2) bioplex_WMM youn_WMM |
| LZTS2 | DYRK1A | 0.87 | 0.803 | youn (LZTS2) bioplex (LZTS2) bioplex_WMM youn_WMM gupta_WMM boldt_WMM |
| LZTS2 | SIPA1L1 | 0.609 | 0.674 | hein_WMM youn (LZTS2) bioplex (LZTS2) bioplex_WMM youn_WMM gupta_WMM boldt_WMM |
| SIPA1L2 | SIPA1L1 | 0.012 | 0.147 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| LZTS1 | SIPA1L1 | 0.009 | 0.093 | bioplex_WMM youn_WMM WMM_only |
| SIPA1L2 | DYRK1A | 0.009 | 0.098 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| SIPA1L2 | LZTS1 | 0.008 | 0.089 | bioplex_WMM youn_WMM WMM_only |
| DYRK1A | LZTS1 | 0.008 | 0.084 | bioplex_WMM youn_WMM WMM_only |
| DYRK1A | SIPA1L1 | 0.008 | 0.032 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
Images
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Complex HuMAP2_03011 has an average edge precision of 0.387 which is ranked 3459 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DYRK1A | HuMAP2_02173 HuMAP2_03011 HuMAP2_05742 |
| SIPA1L1 | HuMAP2_02675 HuMAP2_03011 HuMAP2_03772 |
| LZTS2 | HuMAP2_00618 HuMAP2_02173 HuMAP2_03011 HuMAP2_03772 |
| LZTS1 | HuMAP2_02173 HuMAP2_02337 HuMAP2_03011 HuMAP2_03772 |
| SIPA1L2 | HuMAP2_00035 HuMAP2_00618 HuMAP2_02173 HuMAP2_02612 HuMAP2_03011 HuMAP2_03772 |