hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03027
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| KCNC4 | Potassium voltage-gated channel subfamily C member 4 (KSHIIIC) (Voltage-gated potassium channel subunit Kv3.4) | UniProt NCBI |
| CLUH | Clustered mitochondria protein homolog | UniProt NCBI |
| DCAF4L2 | DDB1- and CUL4-associated factor 4-like protein 2 (WD repeat-containing protein 21C) | UniProt NCBI |
| KCNC3 | Potassium voltage-gated channel subfamily C member 3 (KSHIIID) (Voltage-gated potassium channel subunit Kv3.3) | UniProt NCBI |
| KCNC1 | Potassium voltage-gated channel subfamily C member 1 (NGK2) (Voltage-gated potassium channel subunit Kv3.1) (Voltage-gated potassium channel subunit Kv4) | UniProt NCBI |
| RNF215 | RING finger protein 215 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-1296072 | 3.878939824e-05 | 0.5 | KCNC3 KCNC1 KCNC4 | Voltage gated Potassium channels |
| REAC:R-HSA-1296071 | 0.00036649373235 | 0.5 | KCNC3 KCNC1 KCNC4 | Potassium Channels |
| GO:0032809 | 0.00101517134288 | 0.5 | KCNC3 KCNC1 KCNC4 | neuronal cell body membrane |
| GO:0044298 | 0.00101517134288 | 0.5 | KCNC3 KCNC1 KCNC4 | cell body membrane |
| GO:0032590 | 0.00147880241807 | 0.5 | KCNC3 KCNC1 KCNC4 | dendrite membrane |
| GO:0005251 | 0.00240920978697 | 0.5 | KCNC3 KCNC1 KCNC4 | delayed rectifier potassium channel activity |
| GO:0032589 | 0.00416378298645 | 0.5 | KCNC3 KCNC1 KCNC4 | neuron projection membrane |
| REAC:R-HSA-112316 | 0.0370544697669 | 0.5 | KCNC3 KCNC1 KCNC4 | Neuronal System |
| GO:0005249 | 0.0447070305646 | 0.5 | KCNC3 KCNC1 KCNC4 | voltage-gated potassium channel activity |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| KCNC3 | KCNC4 | 1.0 | 0.949 | bioplex (KCNC4) bioplex_WMM |
| KCNC1 | KCNC4 | 1.0 | 0.949 | bioplex (KCNC4) bioplex_WMM |
| KCNC4 | DCAF4L2 | 0.316 | 0.51 | bioplex (KCNC4) bioplex_WMM |
| CLUH | DCAF4L2 | 0.101 | 0.363 | bioplex (DCAF4L2) bioplex_WMM |
| KCNC4 | RNF215 | 0.088 | 0.352 | bioplex (KCNC4) bioplex_WMM |
| KCNC3 | RNF215 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| KCNC1 | RNF215 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| KCNC1 | KCNC3 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| KCNC1 | DCAF4L2 | 0.008 | 0.091 | bioplex_WMM WMM_only |
| KCNC3 | DCAF4L2 | 0.008 | 0.091 | bioplex_WMM WMM_only |
| RNF215 | DCAF4L2 | 0.008 | 0.091 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_03027 has an average edge precision of 0.335 which is ranked 4182 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| KCNC4 | HuMAP2_00584 HuMAP2_02000 HuMAP2_02901 HuMAP2_03027 HuMAP2_06429 |
| CLUH | HuMAP2_03027 HuMAP2_03701 |
| DCAF4L2 | HuMAP2_03027 HuMAP2_03701 HuMAP2_06429 |
| KCNC3 | HuMAP2_00584 HuMAP2_02000 HuMAP2_02901 HuMAP2_03027 HuMAP2_06429 |
| KCNC1 | HuMAP2_00584 HuMAP2_02901 HuMAP2_03027 HuMAP2_06429 |
| RNF215 | HuMAP2_02901 HuMAP2_03027 HuMAP2_06429 |