hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03045
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RBM10 | RNA-binding protein 10 (G patch domain-containing protein 9) (RNA-binding motif protein 10) (RNA-binding protein S1-1) (S1-1) | UniProt NCBI |
| CHERP | Calcium homeostasis endoplasmic reticulum protein (ERPROT 213-21) (SR-related CTD-associated factor 6) | UniProt NCBI |
| SFSWAP | Splicing factor, suppressor of white-apricot homolog (Splicing factor, arginine/serine-rich 8) (Suppressor of white apricot protein homolog) | UniProt NCBI |
| RBM5 | RNA-binding protein 5 (Protein G15) (Putative tumor suppressor LUCA15) (RNA-binding motif protein 5) (Renal carcinoma antigen NY-REN-9) | UniProt NCBI |
| RBM17 | Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP411 | 0.000211141596217 | 0.6 | SFSWAP RBM5 RBM17 | mRNA Processing |
| REAC:R-HSA-72163 | 0.00246885319177 | 0.6 | CHERP RBM5 RBM17 | mRNA Splicing - Major Pathway |
| REAC:R-HSA-72172 | 0.00281668881241 | 0.6 | CHERP RBM5 RBM17 | mRNA Splicing |
| CORUM:2755 | 0.00331411915188 | 0.4 | CHERP RBM17 | 17S U2 snRNP |
| REAC:R-HSA-72203 | 0.00567167369058 | 0.6 | CHERP RBM5 RBM17 | Processing of Capped Intron-Containing Pre-mRNA |
| HPA:009020_23 | 0.0234185559543 | 0.6 | SFSWAP RBM10 RBM5 | cervix, uterine; squamous epithelial cells[Approved,High] |
| HPA:058010_23 | 0.0324385241997 | 0.6 | SFSWAP RBM10 RBM5 | vagina; squamous epithelial cells[Approved,High] |
| KEGG:03040 | 0.0353865382697 | 0.4 | CHERP RBM17 | Spliceosome |
| HPA:030010_23 | 0.035966530623 | 0.6 | SFSWAP RBM10 RBM5 | oral mucosa; squamous epithelial cells[Approved,High] |
| GO:0000377 | 0.0464577202339 | 0.8 | RBM17 CHERP RBM5 SFSWAP | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile |
| GO:0000398 | 0.0464577202339 | 0.8 | RBM17 CHERP RBM5 SFSWAP | mRNA splicing, via spliceosome |
| GO:0000375 | 0.0482714880996 | 0.8 | RBM17 CHERP RBM5 SFSWAP | RNA splicing, via transesterification reactions |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RBM17 | CHERP | 0.977 | 0.893 | hein_WMM bioplex (RBM17) bioplex_WMM youn_WMM gupta_WMM fraction boldt_WMM |
| RBM10 | RBM17 | 0.147 | 0.408 | hein_WMM bioplex (RBM17) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| RBM5 | RBM17 | 0.119 | 0.392 | hein_WMM bioplex (RBM17) bioplex_WMM youn_WMM |
| SFSWAP | RBM17 | 0.024 | 0.215 | bioplex (RBM17) bioplex_WMM youn_WMM |
| RBM5 | CHERP | 0.012 | 0.149 | hein_WMM bioplex_WMM youn_WMM WMM_only treiber_WMM |
| RBM10 | RBM5 | 0.01 | 0.1 | hein_WMM bioplex_WMM youn_WMM WMM_only treiber_WMM |
| RBM10 | CHERP | 0.009 | 0.111 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| SFSWAP | CHERP | 0.009 | 0.095 | bioplex_WMM youn_WMM WMM_only treiber_WMM |
| SFSWAP | RBM10 | 0.008 | 0.032 | hein_WMM bioplex_WMM youn_WMM WMM_only treiber_WMM |
| SFSWAP | RBM5 | 0.007 | 0.007 | bioplex_WMM youn_WMM WMM_only treiber_WMM |
Images
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Complex HuMAP2_03045 has an average edge precision of 0.24 which is ranked 5520 out of all 6965 complexes.
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