hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03060
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| TASOR2 | Protein TASOR 2 | UniProt NCBI |
| TASOR | Protein TASOR (CTCL tumor antigen se89-1) (Retinoblastoma-associated protein RAP140) (Transgene activation suppressor protein) | UniProt NCBI |
| PPHLN1 | Periphilin-1 (CDC7 expression repressor) (CR) (Gastric cancer antigen Ga50) | UniProt NCBI |
| MPHOSPH8 | M-phase phosphoprotein 8 (Two hybrid-associated protein 3 with RanBPM) (Twa3) | UniProt NCBI |
| ZNF597 | Zinc finger protein 597 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6891 | 1.35146690511e-09 | 0.6 | PPHLN1 MPHOSPH8 TASOR | HUSH complex |
| GO:0090309 | 0.000108905457596 | 0.6 | PPHLN1 MPHOSPH8 TASOR | positive regulation of methylation-dependent chromatin silencing |
| GO:0090308 | 0.000199619769136 | 0.6 | PPHLN1 MPHOSPH8 TASOR | regulation of methylation-dependent chromatin silencing |
| GO:0031937 | 0.000330213415772 | 0.6 | PPHLN1 MPHOSPH8 TASOR | positive regulation of chromatin silencing |
| GO:0006346 | 0.000878614215261 | 0.6 | PPHLN1 MPHOSPH8 TASOR | methylation-dependent chromatin silencing |
| GO:0097355 | 0.00450823411379 | 0.4 | PPHLN1 TASOR | protein localization to heterochromatin |
| GO:0031935 | 0.005924931483 | 0.6 | PPHLN1 MPHOSPH8 TASOR | regulation of chromatin silencing |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TASOR2 | ZNF597 | 0.979 | 0.895 | bioplex (ZNF597) bioplex_WMM |
| MPHOSPH8 | ZNF597 | 0.759 | 0.749 | bioplex (ZNF597) bioplex_WMM |
| MPHOSPH8 | TASOR | 0.047 | 0.291 | hein_WMM hein (MPHOSPH8) |
| ZNF597 | PPHLN1 | 0.041 | 0.27 | bioplex (ZNF597) bioplex_WMM |
| MPHOSPH8 | TASOR2 | 0.039 | 0.264 | hein_WMM bioplex_WMM hein (MPHOSPH8) |
| TASOR2 | PPHLN1 | 0.009 | 0.09 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| TASOR2 | TASOR | 0.009 | 0.096 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| MPHOSPH8 | PPHLN1 | 0.008 | 0.068 | hein_WMM bioplex_WMM WMM_only |
| TASOR | PPHLN1 | 0.007 | 0.011 | hein_WMM bioplex_WMM youn_WMM WMM_only |
Images
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Complex HuMAP2_03060 has an average edge precision of 0.304 which is ranked 4524 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| TASOR2 | HuMAP2_00112 HuMAP2_03060 HuMAP2_04713 |
| TASOR | HuMAP2_00112 HuMAP2_03060 HuMAP2_03471 |
| PPHLN1 | HuMAP2_02572 HuMAP2_03060 HuMAP2_03225 HuMAP2_04668 HuMAP2_06517 |
| MPHOSPH8 | HuMAP2_00112 HuMAP2_03060 HuMAP2_03471 HuMAP2_04713 |
| ZNF597 | HuMAP2_00112 HuMAP2_03060 HuMAP2_04713 HuMAP2_04865 |