hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_03073
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| EXOSC10 | Exosome component 10 (EC 3.1.13.-) (Autoantigen PM/Scl 2) (P100 polymyositis-scleroderma overlap syndrome-associated autoantigen) (Polymyositis/scleroderma autoantigen 100 kDa) (PM/Scl-100) (Polymyositis/scleroderma autoantigen 2) | UniProt NCBI |
| EXOSC3 | Exosome complex component RRP40 (Exosome component 3) (Ribosomal RNA-processing protein 40) (p10) | UniProt NCBI |
| DIS3L | DIS3-like exonuclease 1 (EC 3.1.13.-) | UniProt NCBI |
| EXOSC1 | Exosome complex component CSL4 (Exosome component 1) | UniProt NCBI |
| EXOSC4 | Exosome complex component RRP41 (Exosome component 4) (Ribosomal RNA-processing protein 41) (p12A) | UniProt NCBI |
| EXOSC8 | Exosome complex component RRP43 (Exosome component 8) (Opa-interacting protein 2) (OIP-2) (Ribosomal RNA-processing protein 43) (p9) | UniProt NCBI |
| EXOSC5 | Exosome complex component RRP46 (Chronic myelogenous leukemia tumor antigen 28) (Exosome component 5) (Ribosomal RNA-processing protein 46) (p12B) | UniProt NCBI |
| EXOSC7 | Exosome complex component RRP42 (Exosome component 7) (Ribosomal RNA-processing protein 42) (p8) | UniProt NCBI |
| EXOSC9 | Exosome complex component RRP45 (Autoantigen PM/Scl 1) (Exosome component 9) (P75 polymyositis-scleroderma overlap syndrome-associated autoantigen) (Polymyositis/scleroderma autoantigen 1) (Polymyositis/scleroderma autoantigen 75 kDa) (PM/Scl-75) | UniProt NCBI |
| EXOSC6 | Exosome complex component MTR3 (Exosome component 6) (mRNA transport regulator 3 homolog) (hMtr3) (p11) | UniProt NCBI |
| EXOSC2 | Exosome complex component RRP4 (Exosome component 2) (Ribosomal RNA-processing protein 4) | UniProt NCBI |
| MPHOSPH6 | M-phase phosphoprotein 6 | UniProt NCBI |
| RBM7 | RNA-binding protein 7 (RNA-binding motif protein 7) | UniProt NCBI |
| C1D | Nuclear nucleic acid-binding protein C1D (hC1D) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7443 | 1.95438132474e-38 | 0.857142857143 | MPHOSPH6 EXOSC8 EXOSC6 EXOSC3 EXOSC5 EXOSC9 EXOSC1 EXOSC7 EXOSC10 EXOSC4 DIS3L EXOSC2 | Exosome |
| GO:1905354 | 6.15853321012e-33 | 0.928571428571 | MPHOSPH6 EXOSC8 EXOSC6 EXOSC3 C1D EXOSC9 EXOSC1 EXOSC7 EXOSC10 EXOSC4 EXOSC5 DIS3L EXOSC2 | exoribonuclease complex |
| GO:0000178 | 6.15853321012e-33 | 0.928571428571 | MPHOSPH6 EXOSC8 EXOSC6 EXOSC3 C1D EXOSC9 EXOSC1 EXOSC7 EXOSC10 EXOSC4 EXOSC5 DIS3L EXOSC2 | exosome (RNase complex) |
| GO:0000176 | 3.34189661587e-32 | 0.857142857143 | MPHOSPH6 EXOSC6 EXOSC3 C1D EXOSC8 EXOSC1 EXOSC7 EXOSC10 EXOSC4 EXOSC5 EXOSC9 EXOSC2 | nuclear exosome (RNase complex) |
| CORUM:789 | 3.96757156659e-30 | 0.714285714286 | EXOSC6 EXOSC3 EXOSC5 EXOSC8 EXOSC1 EXOSC7 EXOSC10 EXOSC4 EXOSC9 EXOSC2 | Exosome |
| KEGG:03018 | 3.99129335108e-28 | 0.928571428571 | MPHOSPH6 EXOSC8 EXOSC6 EXOSC3 C1D EXOSC9 EXOSC1 EXOSC7 EXOSC10 EXOSC4 EXOSC5 DIS3L EXOSC2 | RNA degradation |
| CORUM:788 | 1.07370684294e-26 | 0.642857142857 | EXOSC6 EXOSC3 EXOSC5 EXOSC8 EXOSC1 EXOSC2 EXOSC4 EXOSC9 EXOSC7 | Exosome |
| GO:0016075 | 6.58412471667e-24 | 0.714285714286 | EXOSC8 EXOSC6 EXOSC3 EXOSC5 EXOSC9 EXOSC7 EXOSC10 EXOSC4 DIS3L EXOSC2 | rRNA catabolic process |
| REAC:R-HSA-429958 | 5.85039681611e-23 | 0.642857142857 | EXOSC6 EXOSC3 EXOSC5 EXOSC8 EXOSC1 EXOSC2 EXOSC4 EXOSC9 EXOSC7 | mRNA decay by 3' to 5' exoribonuclease |
| REAC:R-HSA-450513 | 1.24283332645e-22 | 0.642857142857 | EXOSC6 EXOSC3 EXOSC5 EXOSC8 EXOSC1 EXOSC2 EXOSC4 EXOSC9 EXOSC7 | Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA |
| REAC:R-HSA-450385 | 1.24283332645e-22 | 0.642857142857 | EXOSC6 EXOSC3 EXOSC5 EXOSC8 EXOSC1 EXOSC2 EXOSC4 EXOSC9 EXOSC7 | Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA |
| REAC:R-HSA-450604 | 1.24283332645e-22 | 0.642857142857 | EXOSC6 EXOSC3 EXOSC5 EXOSC8 EXOSC1 EXOSC2 EXOSC4 EXOSC9 EXOSC7 | KSRP (KHSRP) binds and destabilizes mRNA |
| GO:0071027 | 7.20983998771e-22 | 0.642857142857 | EXOSC6 EXOSC3 EXOSC5 EXOSC8 EXOSC7 EXOSC10 EXOSC4 EXOSC9 EXOSC2 | nuclear RNA surveillance |
| GO:0071028 | 7.20983998771e-22 | 0.642857142857 | EXOSC6 EXOSC3 EXOSC5 EXOSC8 EXOSC7 EXOSC10 EXOSC4 EXOSC9 EXOSC2 | nuclear mRNA surveillance |
| GO:0071025 | 2.01814474932e-21 | 0.642857142857 | EXOSC6 EXOSC3 EXOSC5 EXOSC8 EXOSC7 EXOSC10 EXOSC4 EXOSC9 EXOSC2 | RNA surveillance |
| GO:0000177 | 2.01814474932e-21 | 0.642857142857 | EXOSC8 EXOSC6 EXOSC3 EXOSC5 EXOSC9 EXOSC2 EXOSC4 DIS3L EXOSC7 | cytoplasmic exosome (RNase complex) |
| GO:0034475 | 2.50479191981e-21 | 0.571428571429 | EXOSC6 EXOSC3 EXOSC5 EXOSC9 EXOSC2 EXOSC4 EXOSC8 EXOSC7 | U4 snRNA 3'-end processing |
| REAC:R-HSA-380994 | 6.67038908302e-21 | 0.642857142857 | EXOSC6 EXOSC3 EXOSC5 EXOSC8 EXOSC1 EXOSC2 EXOSC4 EXOSC9 EXOSC7 | ATF4 activates genes in response to endoplasmic reticulum stress |
| GO:0034661 | 6.76129548526e-21 | 0.714285714286 | EXOSC8 EXOSC6 EXOSC3 EXOSC5 EXOSC9 EXOSC7 EXOSC10 EXOSC4 DIS3L EXOSC2 | ncRNA catabolic process |
| GO:0034427 | 2.25350505611e-20 | 0.571428571429 | EXOSC6 EXOSC3 EXOSC5 EXOSC9 EXOSC2 EXOSC4 EXOSC8 EXOSC7 | nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' |
| REAC:R-HSA-381042 | 5.10154931333e-20 | 0.642857142857 | EXOSC6 EXOSC3 EXOSC5 EXOSC8 EXOSC1 EXOSC2 EXOSC4 EXOSC9 EXOSC7 | PERK regulates gene expression |
| GO:0016072 | 6.08148513926e-20 | 0.928571428571 | MPHOSPH6 EXOSC8 EXOSC6 EXOSC3 C1D EXOSC9 EXOSC1 EXOSC7 EXOSC10 EXOSC4 EXOSC5 DIS3L EXOSC2 | rRNA metabolic process |
| REAC:R-HSA-6791226 | 1.62367045733e-19 | 0.857142857143 | MPHOSPH6 EXOSC6 EXOSC3 C1D EXOSC8 EXOSC1 EXOSC7 EXOSC10 EXOSC4 EXOSC5 EXOSC9 EXOSC2 | Major pathway of rRNA processing in the nucleolus and cytosol |
| REAC:R-HSA-8868773 | 3.15399231036e-19 | 0.857142857143 | MPHOSPH6 EXOSC6 EXOSC3 C1D EXOSC8 EXOSC1 EXOSC7 EXOSC10 EXOSC4 EXOSC5 EXOSC9 EXOSC2 | rRNA processing in the nucleus and cytosol |
| REAC:R-HSA-72312 | 5.91615930318e-19 | 0.857142857143 | MPHOSPH6 EXOSC6 EXOSC3 C1D EXOSC8 EXOSC1 EXOSC7 EXOSC10 EXOSC4 EXOSC5 EXOSC9 EXOSC2 | rRNA processing |
| GO:0000460 | 1.31406664936e-18 | 0.642857142857 | MPHOSPH6 EXOSC3 C1D EXOSC8 EXOSC7 EXOSC2 EXOSC4 EXOSC9 EXOSC10 | maturation of 5.8S rRNA |
| GO:0006364 | 1.82874509438e-17 | 0.857142857143 | MPHOSPH6 EXOSC6 EXOSC3 C1D EXOSC8 EXOSC1 EXOSC7 EXOSC10 EXOSC4 EXOSC5 EXOSC9 EXOSC2 | rRNA processing |
| REAC:R-HSA-429914 | 3.82769012331e-17 | 0.642857142857 | EXOSC6 EXOSC3 EXOSC5 EXOSC8 EXOSC1 EXOSC2 EXOSC4 EXOSC9 EXOSC7 | Deadenylation-dependent mRNA decay |
| GO:0043928 | 3.86552257059e-17 | 0.642857142857 | EXOSC6 EXOSC3 EXOSC5 EXOSC8 EXOSC1 EXOSC2 EXOSC4 EXOSC9 EXOSC7 | exonucleolytic catabolism of deadenylated mRNA |
| GO:0016073 | 5.25551916207e-17 | 0.642857142857 | EXOSC6 EXOSC3 EXOSC5 EXOSC8 EXOSC7 EXOSC10 EXOSC4 EXOSC9 EXOSC2 | snRNA metabolic process |
| GO:0000291 | 7.07259540821e-17 | 0.642857142857 | EXOSC6 EXOSC3 EXOSC5 EXOSC8 EXOSC1 EXOSC2 EXOSC4 EXOSC9 EXOSC7 | nuclear-transcribed mRNA catabolic process, exonucleolytic |
| GO:0043628 | 1.24536945618e-16 | 0.642857142857 | EXOSC6 EXOSC3 EXOSC5 EXOSC8 EXOSC7 EXOSC10 EXOSC4 EXOSC9 EXOSC2 | ncRNA 3'-end processing |
| GO:0042254 | 7.95252122855e-16 | 0.857142857143 | MPHOSPH6 EXOSC6 EXOSC3 C1D EXOSC8 EXOSC1 EXOSC7 EXOSC10 EXOSC4 EXOSC5 EXOSC9 EXOSC2 | ribosome biogenesis |
| GO:0034472 | 7.9694767851e-16 | 0.571428571429 | EXOSC6 EXOSC3 EXOSC5 EXOSC9 EXOSC2 EXOSC4 EXOSC8 EXOSC7 | snRNA 3'-end processing |
| REAC:R-HSA-381119 | 1.64714535062e-15 | 0.642857142857 | EXOSC6 EXOSC3 EXOSC5 EXOSC8 EXOSC1 EXOSC2 EXOSC4 EXOSC9 EXOSC7 | Unfolded Protein Response (UPR) |
| REAC:R-HSA-450531 | 1.84424267179e-15 | 0.642857142857 | EXOSC6 EXOSC3 EXOSC5 EXOSC8 EXOSC1 EXOSC2 EXOSC4 EXOSC9 EXOSC7 | Regulation of mRNA stability by proteins that bind AU-rich elements |
| GO:0034660 | 2.20338467863e-15 | 0.928571428571 | MPHOSPH6 EXOSC8 EXOSC6 EXOSC3 C1D EXOSC9 EXOSC1 EXOSC7 EXOSC10 EXOSC4 EXOSC5 DIS3L EXOSC2 | ncRNA metabolic process |
| GO:0016180 | 7.72953119305e-15 | 0.571428571429 | EXOSC6 EXOSC3 EXOSC5 EXOSC9 EXOSC2 EXOSC4 EXOSC8 EXOSC7 | snRNA processing |
| GO:0071038 | 9.91350374775e-15 | 0.428571428571 | EXOSC7 EXOSC3 EXOSC9 EXOSC2 EXOSC8 EXOSC10 | nuclear polyadenylation-dependent tRNA catabolic process |
| GO:0071046 | 9.91350374775e-15 | 0.428571428571 | EXOSC7 EXOSC3 EXOSC9 EXOSC2 EXOSC8 EXOSC10 | nuclear polyadenylation-dependent ncRNA catabolic process |
| GO:0071029 | 9.91350374775e-15 | 0.428571428571 | EXOSC7 EXOSC3 EXOSC9 EXOSC2 EXOSC8 EXOSC10 | nuclear ncRNA surveillance |
| GO:0071035 | 9.91350374775e-15 | 0.428571428571 | EXOSC7 EXOSC3 EXOSC9 EXOSC2 EXOSC8 EXOSC10 | nuclear polyadenylation-dependent rRNA catabolic process |
| GO:0034470 | 2.85052366796e-14 | 0.857142857143 | MPHOSPH6 EXOSC6 EXOSC3 C1D EXOSC8 EXOSC1 EXOSC7 EXOSC10 EXOSC4 EXOSC5 EXOSC9 EXOSC2 | ncRNA processing |
| GO:0000175 | 5.83842919791e-14 | 0.571428571429 | EXOSC7 EXOSC3 EXOSC5 EXOSC9 EXOSC2 EXOSC4 DIS3L EXOSC10 | 3'-5'-exoribonuclease activity |
| GO:0000288 | 6.44552103975e-14 | 0.642857142857 | EXOSC6 EXOSC3 EXOSC5 EXOSC8 EXOSC1 EXOSC2 EXOSC4 EXOSC9 EXOSC7 | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay |
| GO:0071051 | 6.93625643737e-14 | 0.428571428571 | EXOSC6 EXOSC3 EXOSC4 EXOSC2 EXOSC5 EXOSC10 | polyadenylation-dependent snoRNA 3'-end processing |
| GO:0043634 | 6.93625643737e-14 | 0.428571428571 | EXOSC7 EXOSC3 EXOSC9 EXOSC2 EXOSC8 EXOSC10 | polyadenylation-dependent ncRNA catabolic process |
| GO:0016896 | 9.57045269892e-14 | 0.571428571429 | EXOSC7 EXOSC3 EXOSC5 EXOSC9 EXOSC2 EXOSC4 DIS3L EXOSC10 | exoribonuclease activity, producing 5'-phosphomonoesters |
| GO:0004532 | 1.52400351579e-13 | 0.571428571429 | EXOSC7 EXOSC3 EXOSC5 EXOSC9 EXOSC2 EXOSC4 DIS3L EXOSC10 | exoribonuclease activity |
| GO:0022613 | 2.01573199215e-13 | 0.857142857143 | MPHOSPH6 EXOSC6 EXOSC3 C1D EXOSC8 EXOSC1 EXOSC7 EXOSC10 EXOSC4 EXOSC5 EXOSC9 EXOSC2 | ribonucleoprotein complex biogenesis |
| GO:0000467 | 2.77322462653e-13 | 0.428571428571 | EXOSC7 EXOSC3 EXOSC9 EXOSC2 EXOSC8 EXOSC10 | exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| GO:0000459 | 2.77322462653e-13 | 0.428571428571 | EXOSC7 EXOSC3 EXOSC9 EXOSC2 EXOSC8 EXOSC10 | exonucleolytic trimming involved in rRNA processing |
| GO:0043633 | 2.77322462653e-13 | 0.428571428571 | EXOSC7 EXOSC3 EXOSC9 EXOSC2 EXOSC8 EXOSC10 | polyadenylation-dependent RNA catabolic process |
| GO:0016078 | 2.77322462653e-13 | 0.428571428571 | EXOSC7 EXOSC3 EXOSC9 EXOSC2 EXOSC8 EXOSC10 | tRNA catabolic process |
| GO:0031125 | 8.3158416118e-13 | 0.428571428571 | EXOSC7 EXOSC3 EXOSC9 EXOSC2 EXOSC8 EXOSC10 | rRNA 3'-end processing |
| REAC:R-HSA-8953854 | 9.56978073033e-13 | 0.857142857143 | MPHOSPH6 EXOSC6 EXOSC3 C1D EXOSC8 EXOSC1 EXOSC7 EXOSC10 EXOSC4 EXOSC5 EXOSC9 EXOSC2 | Metabolism of RNA |
| GO:0016796 | 2.18449829915e-12 | 0.571428571429 | EXOSC7 EXOSC3 EXOSC5 EXOSC9 EXOSC2 EXOSC4 DIS3L EXOSC10 | exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters |
| GO:0008408 | 2.99875112146e-12 | 0.571428571429 | EXOSC7 EXOSC3 EXOSC5 EXOSC9 EXOSC2 EXOSC4 DIS3L EXOSC10 | 3'-5' exonuclease activity |
| GO:0031126 | 4.56949999347e-12 | 0.428571428571 | EXOSC6 EXOSC3 EXOSC4 EXOSC2 EXOSC5 EXOSC10 | snoRNA 3'-end processing |
| GO:0000956 | 6.22977313395e-12 | 0.714285714286 | EXOSC6 EXOSC3 EXOSC5 EXOSC8 EXOSC1 EXOSC7 EXOSC10 EXOSC4 EXOSC9 EXOSC2 | nuclear-transcribed mRNA catabolic process |
| GO:0006396 | 1.1804846341e-11 | 0.928571428571 | MPHOSPH6 EXOSC8 EXOSC6 RBM7 C1D EXOSC4 EXOSC1 EXOSC7 EXOSC10 EXOSC3 EXOSC5 EXOSC9 EXOSC2 | RNA processing |
| GO:0043144 | 1.6956793535e-11 | 0.428571428571 | EXOSC6 EXOSC3 EXOSC4 EXOSC2 EXOSC5 EXOSC10 | snoRNA processing |
| GO:0090503 | 1.6956793535e-11 | 0.428571428571 | EXOSC7 EXOSC3 EXOSC9 EXOSC2 EXOSC8 EXOSC10 | RNA phosphodiester bond hydrolysis, exonucleolytic |
| GO:0031123 | 2.83548365794e-11 | 0.642857142857 | EXOSC6 EXOSC3 EXOSC5 EXOSC8 EXOSC7 EXOSC10 EXOSC4 EXOSC9 EXOSC2 | RNA 3'-end processing |
| GO:0016074 | 2.96607164956e-11 | 0.428571428571 | EXOSC6 EXOSC3 EXOSC4 EXOSC2 EXOSC5 EXOSC10 | snoRNA metabolic process |
| GO:0006401 | 2.98730658492e-11 | 0.785714285714 | EXOSC8 EXOSC6 EXOSC3 EXOSC5 EXOSC9 EXOSC1 EXOSC7 EXOSC10 EXOSC4 DIS3L EXOSC2 | RNA catabolic process |
| GO:0004527 | 4.60909928272e-11 | 0.571428571429 | EXOSC7 EXOSC3 EXOSC5 EXOSC9 EXOSC2 EXOSC4 DIS3L EXOSC10 | exonuclease activity |
| GO:0000469 | 7.90223706509e-11 | 0.428571428571 | EXOSC7 EXOSC3 EXOSC9 EXOSC2 EXOSC8 EXOSC10 | cleavage involved in rRNA processing |
| GO:0043488 | 1.37101392435e-10 | 0.642857142857 | EXOSC6 EXOSC3 EXOSC5 EXOSC8 EXOSC1 EXOSC2 EXOSC4 EXOSC9 EXOSC7 | regulation of mRNA stability |
| GO:0043487 | 1.7223751102e-10 | 0.642857142857 | EXOSC6 EXOSC3 EXOSC5 EXOSC8 EXOSC1 EXOSC2 EXOSC4 EXOSC9 EXOSC7 | regulation of RNA stability |
| GO:0000466 | 2.67366659896e-10 | 0.428571428571 | EXOSC7 EXOSC3 EXOSC9 EXOSC2 EXOSC8 EXOSC10 | maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| GO:1903311 | 2.72665508442e-10 | 0.714285714286 | EXOSC8 EXOSC6 RBM7 EXOSC5 EXOSC4 EXOSC1 EXOSC2 EXOSC3 EXOSC9 EXOSC7 | regulation of mRNA metabolic process |
| GO:0034655 | 3.54485471027e-10 | 0.785714285714 | EXOSC8 EXOSC6 EXOSC3 EXOSC5 EXOSC9 EXOSC1 EXOSC7 EXOSC10 EXOSC4 DIS3L EXOSC2 | nucleobase-containing compound catabolic process |
| GO:0061013 | 3.86005622654e-10 | 0.642857142857 | EXOSC6 EXOSC3 EXOSC5 EXOSC8 EXOSC1 EXOSC2 EXOSC4 EXOSC9 EXOSC7 | regulation of mRNA catabolic process |
| GO:0004540 | 4.89573123925e-10 | 0.571428571429 | EXOSC7 EXOSC3 EXOSC5 EXOSC9 EXOSC2 EXOSC4 DIS3L EXOSC10 | ribonuclease activity |
| GO:0046700 | 7.97089373316e-10 | 0.785714285714 | EXOSC8 EXOSC6 EXOSC3 EXOSC5 EXOSC9 EXOSC1 EXOSC7 EXOSC10 EXOSC4 DIS3L EXOSC2 | heterocycle catabolic process |
| GO:0044270 | 8.15049862121e-10 | 0.785714285714 | EXOSC8 EXOSC6 EXOSC3 EXOSC5 EXOSC9 EXOSC1 EXOSC7 EXOSC10 EXOSC4 DIS3L EXOSC2 | cellular nitrogen compound catabolic process |
| GO:0019439 | 1.06115871307e-09 | 0.785714285714 | EXOSC8 EXOSC6 EXOSC3 EXOSC5 EXOSC9 EXOSC1 EXOSC7 EXOSC10 EXOSC4 DIS3L EXOSC2 | aromatic compound catabolic process |
| GO:0006402 | 1.42336422711e-09 | 0.714285714286 | EXOSC6 EXOSC3 EXOSC5 EXOSC8 EXOSC1 EXOSC7 EXOSC10 EXOSC4 EXOSC9 EXOSC2 | mRNA catabolic process |
| GO:1901361 | 1.62467396069e-09 | 0.785714285714 | EXOSC8 EXOSC6 EXOSC3 EXOSC5 EXOSC9 EXOSC1 EXOSC7 EXOSC10 EXOSC4 DIS3L EXOSC2 | organic cyclic compound catabolic process |
| GO:1902494 | 3.48567454306e-09 | 0.928571428571 | MPHOSPH6 EXOSC8 EXOSC6 EXOSC3 C1D EXOSC9 EXOSC1 EXOSC7 EXOSC10 EXOSC4 EXOSC5 DIS3L EXOSC2 | catalytic complex |
| GO:0004518 | 2.85124817607e-08 | 0.571428571429 | EXOSC7 EXOSC3 EXOSC5 EXOSC9 EXOSC2 EXOSC4 DIS3L EXOSC10 | nuclease activity |
| GO:0016071 | 4.48019205042e-08 | 0.785714285714 | EXOSC8 EXOSC6 RBM7 EXOSC5 EXOSC4 EXOSC1 EXOSC7 EXOSC10 EXOSC3 EXOSC9 EXOSC2 | mRNA metabolic process |
| CORUM:0000000 | 5.92806466341e-08 | 1.0 | EXOSC8 MPHOSPH6 C1D EXOSC6 RBM7 EXOSC4 EXOSC9 EXOSC1 EXOSC7 EXOSC10 EXOSC3 EXOSC5 DIS3L EXOSC2 | CORUM root |
| GO:0090501 | 1.19320112326e-07 | 0.428571428571 | EXOSC7 EXOSC3 EXOSC9 EXOSC2 EXOSC8 EXOSC10 | RNA phosphodiester bond hydrolysis |
| GO:0044265 | 1.25687631819e-06 | 0.785714285714 | EXOSC8 EXOSC6 EXOSC3 EXOSC5 EXOSC9 EXOSC1 EXOSC7 EXOSC10 EXOSC4 DIS3L EXOSC2 | cellular macromolecule catabolic process |
| GO:0010608 | 3.69738534306e-06 | 0.642857142857 | EXOSC6 EXOSC3 EXOSC5 EXOSC8 EXOSC1 EXOSC2 EXOSC4 EXOSC9 EXOSC7 | posttranscriptional regulation of gene expression |
| GO:0005730 | 4.06465123917e-06 | 0.714285714286 | MPHOSPH6 EXOSC6 EXOSC3 C1D EXOSC1 EXOSC10 EXOSC4 EXOSC5 EXOSC9 EXOSC2 | nucleolus |
| GO:0140098 | 4.11877912208e-06 | 0.571428571429 | EXOSC7 EXOSC3 EXOSC5 EXOSC9 EXOSC2 EXOSC4 DIS3L EXOSC10 | catalytic activity, acting on RNA |
| CORUM:822 | 4.20382511084e-06 | 0.214285714286 | EXOSC4 EXOSC10 EXOSC2 | mRNA decay complex (UPF1, UPF2, UPF3B, DCP2, XRN1, XRN2, EXOSC2, EXOSC4, EXOSC10, PARN) |
| GO:0009057 | 7.13030038292e-06 | 0.785714285714 | EXOSC8 EXOSC6 EXOSC3 EXOSC5 EXOSC9 EXOSC1 EXOSC7 EXOSC10 EXOSC4 DIS3L EXOSC2 | macromolecule catabolic process |
| GO:0045006 | 8.02832390368e-06 | 0.285714285714 | EXOSC3 EXOSC5 EXOSC6 EXOSC4 | DNA deamination |
| GO:0016070 | 1.47008876045e-05 | 1.0 | EXOSC8 MPHOSPH6 C1D EXOSC6 RBM7 EXOSC4 EXOSC9 EXOSC1 EXOSC7 EXOSC10 EXOSC3 EXOSC5 DIS3L EXOSC2 | RNA metabolic process |
| GO:0034476 | 3.30579616724e-05 | 0.214285714286 | EXOSC7 EXOSC9 EXOSC8 | U5 snRNA 3'-end processing |
| GO:0034473 | 3.30579616724e-05 | 0.214285714286 | EXOSC7 EXOSC9 EXOSC8 | U1 snRNA 3'-end processing |
| GO:0090305 | 5.08199048227e-05 | 0.428571428571 | EXOSC7 EXOSC3 EXOSC9 EXOSC2 EXOSC8 EXOSC10 | nucleic acid phosphodiester bond hydrolysis |
| GO:0031329 | 6.0852136548e-05 | 0.642857142857 | EXOSC6 EXOSC3 EXOSC5 EXOSC8 EXOSC1 EXOSC2 EXOSC4 EXOSC9 EXOSC7 | regulation of cellular catabolic process |
| GO:0090304 | 7.37365343152e-05 | 1.0 | EXOSC8 MPHOSPH6 C1D EXOSC6 RBM7 EXOSC4 EXOSC9 EXOSC1 EXOSC7 EXOSC10 EXOSC3 EXOSC5 DIS3L EXOSC2 | nucleic acid metabolic process |
| GO:0003723 | 8.47532827764e-05 | 0.785714285714 | EXOSC8 EXOSC6 RBM7 C1D EXOSC4 EXOSC1 EXOSC7 EXOSC10 EXOSC3 EXOSC9 EXOSC2 | RNA binding |
| GO:0071047 | 0.000132158586819 | 0.214285714286 | EXOSC7 EXOSC9 EXOSC8 | polyadenylation-dependent mRNA catabolic process |
| GO:0071043 | 0.000132158586819 | 0.214285714286 | EXOSC3 EXOSC10 EXOSC2 | CUT metabolic process |
| GO:0071042 | 0.000132158586819 | 0.214285714286 | EXOSC7 EXOSC9 EXOSC8 | nuclear polyadenylation-dependent mRNA catabolic process |
| GO:0071034 | 0.000132158586819 | 0.214285714286 | EXOSC3 EXOSC10 EXOSC2 | CUT catabolic process |
| GO:0006399 | 0.000138028015822 | 0.428571428571 | EXOSC7 EXOSC3 EXOSC9 EXOSC2 EXOSC8 EXOSC10 | tRNA metabolic process |
| GO:0035327 | 0.000176911827793 | 0.285714285714 | EXOSC3 EXOSC5 EXOSC10 EXOSC4 | transcriptionally active chromatin |
| GO:0009894 | 0.000228733977054 | 0.642857142857 | EXOSC6 EXOSC3 EXOSC5 EXOSC8 EXOSC1 EXOSC2 EXOSC4 EXOSC9 EXOSC7 | regulation of catabolic process |
| GO:0071033 | 0.000330213415772 | 0.214285714286 | EXOSC3 EXOSC10 EXOSC2 | nuclear retention of pre-mRNA at the site of transcription |
| GO:0006139 | 0.000343883678144 | 1.0 | EXOSC8 MPHOSPH6 C1D EXOSC6 RBM7 EXOSC4 EXOSC9 EXOSC1 EXOSC7 EXOSC10 EXOSC3 EXOSC5 DIS3L EXOSC2 | nucleobase-containing compound metabolic process |
| GO:1901575 | 0.000486420134489 | 0.785714285714 | EXOSC8 EXOSC6 EXOSC3 EXOSC5 EXOSC9 EXOSC1 EXOSC7 EXOSC10 EXOSC4 DIS3L EXOSC2 | organic substance catabolic process |
| GO:0016788 | 0.000501142869399 | 0.571428571429 | EXOSC7 EXOSC3 EXOSC5 EXOSC9 EXOSC2 EXOSC4 DIS3L EXOSC10 | hydrolase activity, acting on ester bonds |
| GO:0046483 | 0.000558393005317 | 1.0 | EXOSC8 MPHOSPH6 C1D EXOSC6 RBM7 EXOSC4 EXOSC9 EXOSC1 EXOSC7 EXOSC10 EXOSC3 EXOSC5 DIS3L EXOSC2 | heterocycle metabolic process |
| GO:0006725 | 0.000586204207692 | 1.0 | EXOSC8 MPHOSPH6 C1D EXOSC6 RBM7 EXOSC4 EXOSC9 EXOSC1 EXOSC7 EXOSC10 EXOSC3 EXOSC5 DIS3L EXOSC2 | cellular aromatic compound metabolic process |
| GO:1901360 | 0.00100307278591 | 1.0 | EXOSC8 MPHOSPH6 C1D EXOSC6 RBM7 EXOSC4 EXOSC9 EXOSC1 EXOSC7 EXOSC10 EXOSC3 EXOSC5 DIS3L EXOSC2 | organic cyclic compound metabolic process |
| GO:0005654 | 0.00109001791933 | 0.928571428571 | MPHOSPH6 EXOSC8 EXOSC6 RBM7 C1D EXOSC4 EXOSC1 EXOSC7 EXOSC10 EXOSC3 EXOSC5 EXOSC9 EXOSC2 | nucleoplasm |
| GO:0044248 | 0.00112167908609 | 0.785714285714 | EXOSC8 EXOSC6 EXOSC3 EXOSC5 EXOSC9 EXOSC1 EXOSC7 EXOSC10 EXOSC4 DIS3L EXOSC2 | cellular catabolic process |
| GO:0044085 | 0.00147764889148 | 0.857142857143 | MPHOSPH6 EXOSC6 EXOSC3 C1D EXOSC8 EXOSC1 EXOSC7 EXOSC10 EXOSC4 EXOSC5 EXOSC9 EXOSC2 | cellular component biogenesis |
| REAC:R-HSA-392499 | 0.00161671230272 | 0.642857142857 | EXOSC6 EXOSC3 EXOSC5 EXOSC8 EXOSC1 EXOSC2 EXOSC4 EXOSC9 EXOSC7 | Metabolism of proteins |
| GO:0010629 | 0.00202150466201 | 0.714285714286 | EXOSC6 EXOSC3 EXOSC5 EXOSC8 EXOSC1 EXOSC7 EXOSC10 EXOSC4 EXOSC9 EXOSC2 | negative regulation of gene expression |
| GO:0034641 | 0.00218474120888 | 1.0 | EXOSC8 MPHOSPH6 C1D EXOSC6 RBM7 EXOSC4 EXOSC9 EXOSC1 EXOSC7 EXOSC10 EXOSC3 EXOSC5 DIS3L EXOSC2 | cellular nitrogen compound metabolic process |
| WP:WP4352 | 0.00258045925864 | 0.285714285714 | EXOSC4 EXOSC7 EXOSC9 EXOSC2 | Ciliary landscape |
| GO:0009056 | 0.00385267121816 | 0.785714285714 | EXOSC8 EXOSC6 EXOSC3 EXOSC5 EXOSC9 EXOSC1 EXOSC7 EXOSC10 EXOSC4 DIS3L EXOSC2 | catabolic process |
| GO:0008298 | 0.00543043333429 | 0.214285714286 | EXOSC3 EXOSC10 EXOSC2 | intracellular mRNA localization |
| KEGG:00000 | 0.00545659360645 | 0.928571428571 | MPHOSPH6 EXOSC8 EXOSC6 EXOSC3 C1D EXOSC9 EXOSC1 EXOSC7 EXOSC10 EXOSC4 EXOSC5 DIS3L EXOSC2 | KEGG root term |
| GO:0010467 | 0.00672482104923 | 0.928571428571 | MPHOSPH6 EXOSC8 EXOSC6 RBM7 C1D EXOSC4 EXOSC1 EXOSC7 EXOSC10 EXOSC3 EXOSC5 EXOSC9 EXOSC2 | gene expression |
| GO:0031981 | 0.0120655494198 | 0.928571428571 | MPHOSPH6 EXOSC8 EXOSC6 RBM7 C1D EXOSC4 EXOSC1 EXOSC7 EXOSC10 EXOSC3 EXOSC5 EXOSC9 EXOSC2 | nuclear lumen |
| GO:0044428 | 0.0272266468725 | 0.928571428571 | MPHOSPH6 EXOSC8 EXOSC6 RBM7 C1D EXOSC4 EXOSC1 EXOSC7 EXOSC10 EXOSC3 EXOSC5 EXOSC9 EXOSC2 | nuclear part |
| GO:0003676 | 0.0360464318196 | 0.785714285714 | EXOSC8 EXOSC6 RBM7 C1D EXOSC4 EXOSC1 EXOSC7 EXOSC10 EXOSC3 EXOSC9 EXOSC2 | nucleic acid binding |
| GO:0019219 | 0.0378801391776 | 0.785714285714 | EXOSC8 EXOSC6 RBM7 EXOSC5 EXOSC4 EXOSC1 EXOSC7 EXOSC10 EXOSC3 EXOSC9 EXOSC2 | regulation of nucleobase-containing compound metabolic process |
| GO:0006304 | 0.0389794635019 | 0.285714285714 | EXOSC3 EXOSC5 EXOSC6 EXOSC4 | DNA modification |
| GO:0010605 | 0.0392011017908 | 0.714285714286 | EXOSC6 EXOSC3 EXOSC5 EXOSC8 EXOSC1 EXOSC7 EXOSC10 EXOSC4 EXOSC9 EXOSC2 | negative regulation of macromolecule metabolic process |
| GO:0071049 | 0.0410249304355 | 0.142857142857 | EXOSC3 EXOSC2 | nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription |
| GO:0071031 | 0.0410249304355 | 0.142857142857 | EXOSC3 EXOSC2 | nuclear mRNA surveillance of mRNA 3'-end processing |
| GO:0032991 | 0.0456536685194 | 0.928571428571 | MPHOSPH6 EXOSC8 EXOSC6 EXOSC3 C1D EXOSC9 EXOSC1 EXOSC7 EXOSC10 EXOSC4 EXOSC5 DIS3L EXOSC2 | protein-containing complex |
| CORUM:2004 | 0.0499987143188 | 0.0714285714286 | C1D | C1D homodimer protein |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| EXOSC2 | EXOSC10 | 1.0 | 0.949 | hein_WMM youn (EXOSC10) bioplex_WMM Guru youn_WMM hein (EXOSC2) Malo gupta_WMM fraction |
| EXOSC1 | EXOSC10 | 1.0 | 0.949 | hein_WMM youn (EXOSC10) bioplex (EXOSC1) bioplex_WMM Guru youn_WMM hein (EXOSC1) Malo gupta_WMM fraction |
| EXOSC3 | EXOSC5 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC3) bioplex_WMM Guru youn_WMM hein (EXOSC5) Malo gupta_WMM fraction |
| EXOSC2 | EXOSC3 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC3) bioplex_WMM Guru youn_WMM hein (EXOSC2) Malo gupta_WMM fraction treiber_WMM |
| EXOSC9 | EXOSC7 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC7) bioplex_WMM Guru boldt youn_WMM hein (EXOSC9) Malo gupta_WMM fraction boldt_WMM |
| MPHOSPH6 | EXOSC1 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC1) bioplex_WMM youn_WMM hein (EXOSC1) Malo gupta_WMM fraction |
| EXOSC4 | EXOSC2 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru boldt youn_WMM hein (EXOSC2,EXOSC4) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| EXOSC2 | EXOSC7 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC7) bioplex_WMM Guru boldt youn_WMM hein (EXOSC2) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| EXOSC9 | EXOSC3 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC3) bioplex_WMM Guru youn_WMM hein (EXOSC9) Malo gupta_WMM fraction |
| EXOSC4 | EXOSC3 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC3) bioplex_WMM Guru youn_WMM hein (EXOSC4) Malo gupta_WMM fraction treiber_WMM |
| EXOSC10 | EXOSC8 | 1.0 | 0.949 | hein_WMM youn (EXOSC10) bioplex (EXOSC8) bioplex_WMM youn_WMM Malo gupta_WMM fraction |
| EXOSC10 | EXOSC7 | 1.0 | 0.949 | hein_WMM youn (EXOSC10) bioplex (EXOSC7) bioplex_WMM Guru youn_WMM Malo gupta_WMM fraction |
| EXOSC2 | EXOSC1 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC1) bioplex_WMM Guru youn_WMM hein (EXOSC1,EXOSC2) Malo gupta_WMM fraction |
| EXOSC4 | EXOSC7 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC7) bioplex_WMM Guru boldt youn_WMM hein (EXOSC4) Malo gupta_WMM fraction boldt_WMM |
| EXOSC1 | EXOSC3 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC1,EXOSC3) bioplex_WMM Guru youn_WMM hein (EXOSC1) Malo gupta_WMM fraction |
| EXOSC10 | EXOSC9 | 1.0 | 0.949 | hein_WMM youn (EXOSC10) bioplex_WMM Guru youn_WMM hein (EXOSC9) Malo gupta_WMM fraction treiber_WMM |
| EXOSC4 | EXOSC1 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC1) bioplex_WMM Guru youn_WMM hein (EXOSC1,EXOSC4) Malo gupta_WMM fraction |
| EXOSC3 | DIS3L | 1.0 | 0.949 | hein_WMM bioplex (EXOSC3) bioplex_WMM youn_WMM hein (DIS3L) gupta_WMM |
| EXOSC1 | EXOSC8 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC1,EXOSC8) bioplex_WMM youn_WMM hein (EXOSC1) Malo gupta_WMM fraction |
| EXOSC2 | EXOSC9 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru boldt youn_WMM hein (EXOSC2,EXOSC9) Malo gupta_WMM fraction boldt_WMM |
| EXOSC1 | EXOSC7 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC1,EXOSC7) bioplex_WMM Guru youn_WMM hein (EXOSC1) Malo gupta_WMM fraction |
| EXOSC1 | EXOSC9 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC1) bioplex_WMM Guru youn_WMM hein (EXOSC1,EXOSC9) Malo gupta_WMM fraction |
| EXOSC3 | EXOSC7 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC3,EXOSC7) bioplex_WMM Guru youn_WMM Malo gupta_WMM fraction |
| EXOSC9 | EXOSC5 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru youn_WMM hein (EXOSC5,EXOSC9) Malo gupta_WMM fraction |
| EXOSC10 | EXOSC5 | 1.0 | 0.949 | hein_WMM youn (EXOSC10) bioplex_WMM Guru youn_WMM hein (EXOSC5) Malo gupta_WMM fraction |
| EXOSC4 | EXOSC10 | 1.0 | 0.949 | hein_WMM youn (EXOSC10) bioplex_WMM Guru youn_WMM hein (EXOSC4) Malo gupta_WMM fraction |
| EXOSC4 | EXOSC9 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru boldt youn_WMM hein (EXOSC4,EXOSC9) Malo gupta_WMM fraction boldt_WMM |
| EXOSC2 | EXOSC5 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru youn_WMM hein (EXOSC2,EXOSC5) Malo gupta_WMM fraction |
| EXOSC9 | EXOSC8 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC8) bioplex_WMM youn_WMM hein (EXOSC9) gupta_WMM |
| EXOSC8 | EXOSC5 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC8) bioplex_WMM youn_WMM hein (EXOSC5) Malo gupta_WMM fraction |
| EXOSC2 | MPHOSPH6 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru youn_WMM hein (EXOSC2) Malo gupta_WMM fraction |
| EXOSC2 | EXOSC8 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC8) bioplex_WMM youn_WMM hein (EXOSC2) Malo gupta_WMM fraction treiber_WMM |
| EXOSC4 | MPHOSPH6 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru youn_WMM hein (EXOSC4) Malo gupta_WMM fraction |
| EXOSC1 | EXOSC5 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC1) bioplex_WMM Guru youn_WMM hein (EXOSC1,EXOSC5) Malo gupta_WMM fraction |
| EXOSC10 | EXOSC3 | 1.0 | 0.949 | hein_WMM youn (EXOSC10) bioplex (EXOSC3) bioplex_WMM Guru youn_WMM Malo gupta_WMM fraction |
| EXOSC4 | EXOSC8 | 1.0 | 0.949 | hein_WMM bioplex (EXOSC8) bioplex_WMM youn_WMM hein (EXOSC4) gupta_WMM treiber_WMM |
| MPHOSPH6 | EXOSC5 | 0.999 | 0.949 | hein_WMM bioplex_WMM Guru youn_WMM hein (EXOSC5) Malo gupta_WMM fraction |
| EXOSC6 | EXOSC3 | 0.999 | 0.949 | hein_WMM bioplex (EXOSC3) bioplex_WMM youn_WMM Malo gupta_WMM fraction |
| EXOSC5 | EXOSC7 | 0.999 | 0.948 | hein_WMM bioplex (EXOSC7) bioplex_WMM Guru youn_WMM hein (EXOSC5) Malo gupta_WMM fraction |
| DIS3L | EXOSC8 | 0.999 | 0.948 | hein_WMM bioplex (EXOSC8) bioplex_WMM youn_WMM hein (DIS3L) |
| MPHOSPH6 | EXOSC7 | 0.999 | 0.946 | hein_WMM bioplex (EXOSC7) bioplex_WMM Guru youn_WMM Malo gupta_WMM fraction |
| EXOSC4 | EXOSC6 | 0.997 | 0.931 | hein_WMM bioplex_WMM youn_WMM hein (EXOSC4) Malo gupta_WMM fraction |
| DIS3L | EXOSC7 | 0.996 | 0.927 | hein_WMM bioplex (EXOSC7) bioplex_WMM youn_WMM gupta_WMM |
| MPHOSPH6 | EXOSC9 | 0.995 | 0.924 | hein_WMM bioplex_WMM youn_WMM hein (EXOSC9) Malo gupta_WMM fraction |
| MPHOSPH6 | EXOSC10 | 0.993 | 0.918 | hein_WMM youn (EXOSC10) bioplex_WMM Guru youn_WMM Malo gupta_WMM fraction |
| MPHOSPH6 | EXOSC3 | 0.992 | 0.912 | hein_WMM bioplex (EXOSC3) bioplex_WMM Guru youn_WMM Malo gupta_WMM fraction |
| EXOSC1 | DIS3L | 0.99 | 0.907 | hein_WMM bioplex (EXOSC1) bioplex_WMM youn_WMM hein (EXOSC1) |
| EXOSC2 | EXOSC6 | 0.989 | 0.903 | hein_WMM bioplex_WMM youn_WMM hein (EXOSC2) Malo gupta_WMM fraction |
| EXOSC4 | EXOSC5 | 0.988 | 0.902 | hein_WMM bioplex_WMM Guru youn_WMM hein (EXOSC4,EXOSC5) Malo gupta_WMM fraction |
| EXOSC8 | EXOSC7 | 0.978 | 0.894 | hein_WMM bioplex (EXOSC7,EXOSC8) bioplex_WMM youn_WMM gupta_WMM |
| RBM7 | EXOSC3 | 0.975 | 0.887 | hein_WMM bioplex (EXOSC3) bioplex_WMM youn_WMM hein (RBM7) |
| C1D | EXOSC5 | 0.972 | 0.886 | hein_WMM bioplex (C1D) bioplex_WMM youn_WMM hein (EXOSC5) fraction |
| EXOSC3 | EXOSC8 | 0.969 | 0.881 | hein_WMM bioplex (EXOSC3,EXOSC8) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| EXOSC10 | C1D | 0.96 | 0.865 | hein_WMM youn (EXOSC10) bioplex (C1D) bioplex_WMM |
| EXOSC3 | C1D | 0.945 | 0.856 | hein_WMM bioplex (C1D,EXOSC3) bioplex_WMM youn_WMM |
| C1D | EXOSC7 | 0.939 | 0.851 | hein_WMM bioplex (C1D,EXOSC7) bioplex_WMM youn_WMM |
| RBM7 | EXOSC10 | 0.938 | 0.85 | hein_WMM youn (EXOSC10) bioplex (RBM7) bioplex_WMM youn_WMM hein (RBM7) |
| RBM7 | EXOSC7 | 0.919 | 0.842 | bioplex (EXOSC7,RBM7) bioplex_WMM youn_WMM |
| EXOSC1 | EXOSC6 | 0.894 | 0.82 | hein_WMM bioplex (EXOSC1) bioplex_WMM youn_WMM hein (EXOSC1) gupta_WMM |
| EXOSC6 | EXOSC7 | 0.875 | 0.807 | hein_WMM bioplex (EXOSC7) bioplex_WMM youn_WMM gupta_WMM |
| EXOSC9 | C1D | 0.866 | 0.801 | hein_WMM bioplex (C1D) bioplex_WMM youn_WMM hein (EXOSC9) |
| EXOSC1 | C1D | 0.865 | 0.801 | hein_WMM bioplex (C1D,EXOSC1) bioplex_WMM youn_WMM hein (EXOSC1) |
| MPHOSPH6 | EXOSC6 | 0.844 | 0.788 | hein_WMM bioplex_WMM youn_WMM Malo gupta_WMM fraction |
| EXOSC4 | C1D | 0.726 | 0.736 | hein_WMM bioplex (C1D) bioplex_WMM youn_WMM |
| MPHOSPH6 | EXOSC8 | 0.686 | 0.712 | hein_WMM bioplex (EXOSC8) bioplex_WMM youn_WMM Malo gupta_WMM fraction |
| C1D | EXOSC8 | 0.599 | 0.67 | hein_WMM bioplex (C1D,EXOSC8) bioplex_WMM youn_WMM fraction |
| RBM7 | EXOSC8 | 0.531 | 0.636 | bioplex (EXOSC8) bioplex_WMM youn_WMM |
| EXOSC6 | EXOSC5 | 0.525 | 0.635 | hein_WMM bioplex_WMM youn_WMM hein (EXOSC5) Malo gupta_WMM fraction |
| EXOSC2 | C1D | 0.265 | 0.482 | hein_WMM bioplex (C1D) bioplex_WMM youn_WMM fraction |
| EXOSC6 | C1D | 0.237 | 0.47 | hein_WMM bioplex (C1D) bioplex_WMM youn_WMM |
| EXOSC2 | DIS3L | 0.078 | 0.352 | hein_WMM bioplex_WMM youn_WMM hein (DIS3L,EXOSC2) gupta_WMM |
| RBM7 | C1D | 0.072 | 0.354 | bioplex (C1D) bioplex_WMM youn_WMM |
| MPHOSPH6 | C1D | 0.052 | 0.302 | hein_WMM bioplex (C1D) bioplex_WMM youn_WMM fraction |
| EXOSC4 | DIS3L | 0.044 | 0.279 | hein_WMM bioplex_WMM youn_WMM hein (DIS3L,EXOSC4) |
| RBM7 | EXOSC1 | 0.041 | 0.27 | hein_WMM bioplex (EXOSC1) bioplex_WMM youn_WMM hein (RBM7) |
| DIS3L | EXOSC5 | 0.038 | 0.264 | hein_WMM bioplex_WMM youn_WMM hein (DIS3L,EXOSC5) |
| EXOSC10 | EXOSC6 | 0.03 | 0.233 | hein_WMM youn (EXOSC10) bioplex_WMM youn_WMM gupta_WMM |
| EXOSC9 | EXOSC6 | 0.028 | 0.231 | hein_WMM bioplex_WMM youn_WMM hein (EXOSC9) Malo gupta_WMM fraction |
| EXOSC9 | DIS3L | 0.027 | 0.225 | hein_WMM bioplex_WMM youn_WMM hein (DIS3L,EXOSC9) |
| EXOSC6 | EXOSC8 | 0.025 | 0.21 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| MPHOSPH6 | DIS3L | 0.022 | 0.204 | hein_WMM bioplex_WMM WMM_only |
| DIS3L | C1D | 0.021 | 0.195 | hein_WMM bioplex_WMM WMM_only |
| EXOSC6 | DIS3L | 0.017 | 0.171 | hein_WMM bioplex_WMM youn_WMM hein (DIS3L) gupta_WMM |
| RBM7 | MPHOSPH6 | 0.014 | 0.142 | bioplex_WMM youn_WMM WMM_only |
| EXOSC4 | RBM7 | 0.012 | 0.149 | bioplex_WMM youn_WMM WMM_only |
| EXOSC10 | DIS3L | 0.011 | 0.144 | hein_WMM bioplex_WMM youn_WMM hein (DIS3L) gupta_WMM |
| EXOSC2 | RBM7 | 0.011 | 0.14 | bioplex (RBM7) bioplex_WMM youn_WMM |
| RBM7 | DIS3L | 0.01 | 0.126 | bioplex_WMM youn_WMM WMM_only |
| RBM7 | EXOSC5 | 0.004 | 0.01 | hein_WMM bioplex_WMM youn_WMM hein (RBM7) |
| RBM7 | EXOSC9 | 0.003 | 0.015 | hein_WMM bioplex (RBM7) bioplex_WMM youn_WMM hein (RBM7) |
| RBM7 | EXOSC6 | 0.0 | 0.012 | hein_WMM bioplex (RBM7) bioplex_WMM youn_WMM hein (RBM7) |
Images
Click to enlarge
Complex HuMAP2_03073 has an average edge precision of 0.73 which is ranked 1263 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| EXOSC10 | HuMAP2_02326 HuMAP2_03073 HuMAP2_05790 |
| EXOSC3 | HuMAP2_03073 HuMAP2_05790 HuMAP2_06861 |
| DIS3L | HuMAP2_03073 HuMAP2_05790 |
| EXOSC1 | HuMAP2_02326 HuMAP2_03073 HuMAP2_05790 |
| EXOSC4 | HuMAP2_00994 HuMAP2_03073 HuMAP2_05790 |
| EXOSC8 | HuMAP2_03073 HuMAP2_05790 |
| EXOSC5 | HuMAP2_03073 HuMAP2_05790 HuMAP2_06861 |
| EXOSC7 | HuMAP2_03073 HuMAP2_05790 |
| EXOSC9 | HuMAP2_03073 HuMAP2_05790 |
| EXOSC6 | HuMAP2_03073 HuMAP2_05790 |
| EXOSC2 | HuMAP2_00994 HuMAP2_03073 HuMAP2_05790 |
| MPHOSPH6 | HuMAP2_01835 HuMAP2_02326 HuMAP2_03073 HuMAP2_05790 |
| RBM7 | HuMAP2_01425 HuMAP2_01715 HuMAP2_03073 HuMAP2_05790 |
| C1D | HuMAP2_03073 HuMAP2_05790 |