hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03083
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| KIF5B | Kinesin-1 heavy chain (Conventional kinesin heavy chain) (Ubiquitous kinesin heavy chain) (UKHC) | UniProt NCBI |
| KLC4 | Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8) | UniProt NCBI |
| KLC2 | Kinesin light chain 2 (KLC 2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5625970 | 7.41834903159e-08 | 1.0 | KLC4 KIF5B KLC2 | RHO GTPases activate KTN1 |
| REAC:R-HSA-983189 | 1.3155205616e-05 | 1.0 | KLC4 KIF5B KLC2 | Kinesins |
| REAC:R-HSA-6811434 | 6.42384066445e-05 | 1.0 | KLC4 KIF5B KLC2 | COPI-dependent Golgi-to-ER retrograde traffic |
| REAC:R-HSA-2132295 | 0.000113954833063 | 1.0 | KLC4 KIF5B KLC2 | MHC class II antigen presentation |
| REAC:R-HSA-8856688 | 0.000160847790881 | 1.0 | KLC4 KIF5B KLC2 | Golgi-to-ER retrograde transport |
| REAC:R-HSA-983231 | 0.000295546575822 | 1.0 | KLC4 KIF5B KLC2 | Factors involved in megakaryocyte development and platelet production |
| REAC:R-HSA-6811442 | 0.000564194667652 | 1.0 | KLC4 KIF5B KLC2 | Intra-Golgi and retrograde Golgi-to-ER traffic |
| KEGG:05132 | 0.000987288198645 | 0.666666666667 | KLC2 KLC4 | Salmonella infection |
| REAC:R-HSA-195258 | 0.00218937240413 | 1.0 | KLC4 KIF5B KLC2 | RHO GTPase Effectors |
| REAC:R-HSA-194315 | 0.00591618280835 | 1.0 | KLC4 KIF5B KLC2 | Signaling by Rho GTPases |
| REAC:R-HSA-109582 | 0.0114744505078 | 1.0 | KLC4 KIF5B KLC2 | Hemostasis |
| REAC:R-HSA-199991 | 0.0146202486223 | 1.0 | KLC4 KIF5B KLC2 | Membrane Trafficking |
| REAC:R-HSA-5653656 | 0.0171761243356 | 1.0 | KLC4 KIF5B KLC2 | Vesicle-mediated transport |
| REAC:R-HSA-1280218 | 0.0202947578047 | 1.0 | KLC4 KIF5B KLC2 | Adaptive Immune System |
| CORUM:5401 | 0.0499776345577 | 0.333333333333 | KIF5B | PLEKHM2-KIF5B complex |
| CORUM:6552 | 0.0499776345577 | 0.333333333333 | KIF5B | KIF5B-SPG33 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| KIF5B | KLC2 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru boldt youn_WMM hein (KIF5B,KLC2) gupta_WMM fraction boldt_WMM treiber_WMM |
| KIF5B | KLC4 | 0.916 | 0.839 | hein_WMM bioplex_WMM Guru boldt youn_WMM hein (KIF5B,KLC4) gupta_WMM fraction boldt_WMM treiber_WMM |
| KLC2 | KLC4 | 0.636 | 0.684 | hein_WMM bioplex_WMM boldt youn_WMM hein (KLC2,KLC4) gupta_WMM boldt_WMM treiber_WMM |
Images
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Complex HuMAP2_03083 has an average edge precision of 0.824 which is ranked 860 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| KIF5B | HuMAP2_01759 HuMAP2_03083 HuMAP2_06530 |
| KLC4 | HuMAP2_01759 HuMAP2_03083 HuMAP2_06530 |
| KLC2 | HuMAP2_01759 HuMAP2_03083 HuMAP2_06475 HuMAP2_06530 |