hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03084
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| VSIG2 | V-set and immunoglobulin domain-containing protein 2 (Cortical thymocyte-like protein) (CT-like protein) | UniProt NCBI |
| TNPO1 | Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP) | UniProt NCBI |
| XPO6 | Exportin-6 (Exp6) (Ran-binding protein 20) | UniProt NCBI |
| XPO7 | Exportin-7 (Exp7) (Ran-binding protein 16) | UniProt NCBI |
| XPO5 | Exportin-5 (Exp5) (Ran-binding protein 21) | UniProt NCBI |
| THADA | Thyroid adenoma-associated protein (Gene inducing thyroid adenomas protein) | UniProt NCBI |
| TNPO3 | Transportin-3 (Importin-12) (Imp12) (Transportin-SR) (TRN-SR) | UniProt NCBI |
| CIP2A | Protein CIP2A (Cancerous inhibitor of PP2A) (p90 autoantigen) | UniProt NCBI |
| IPO11 | Importin-11 (Imp11) (Ran-binding protein 11) (RanBP11) | UniProt NCBI |
| ATXN10 | Ataxin-10 (Brain protein E46 homolog) (Spinocerebellar ataxia type 10 protein) | UniProt NCBI |
| FANCD2 | Fanconi anemia group D2 protein (Protein FACD2) | UniProt NCBI |
| XPO4 | Exportin-4 (Exp4) | UniProt NCBI |
| SAAL1 | Protein SAAL1 (Synoviocyte proliferation-associated in collagen-induced arthritis protein 1) (SPACIA1) | UniProt NCBI |
| TNPO2 | Transportin-2 (Karyopherin beta-2b) | UniProt NCBI |
| HEATR3 | HEAT repeat-containing protein 3 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0140142 | 7.6955499646e-13 | 0.466666666667 | XPO7 XPO4 XPO5 TNPO3 XPO6 TNPO1 TNPO2 | nucleocytoplasmic carrier activity |
| GO:0006913 | 3.93959238514e-08 | 0.6 | XPO7 XPO4 XPO6 HEATR3 TNPO3 XPO5 TNPO2 TNPO1 IPO11 | nucleocytoplasmic transport |
| GO:0051169 | 4.35653867856e-08 | 0.6 | XPO7 XPO4 XPO6 HEATR3 TNPO3 XPO5 TNPO2 TNPO1 IPO11 | nuclear transport |
| GO:0005049 | 1.09435954146e-05 | 0.266666666667 | XPO6 XPO5 XPO4 XPO7 | nuclear export signal receptor activity |
| GO:0006606 | 0.0016691238358 | 0.333333333333 | TNPO3 TNPO1 IPO11 HEATR3 TNPO2 | protein import into nucleus |
| GO:0006886 | 0.00222756052796 | 0.6 | XPO7 XPO4 XPO6 HEATR3 TNPO3 XPO5 TNPO2 TNPO1 IPO11 | intracellular protein transport |
| GO:0061608 | 0.00345851718181 | 0.2 | TNPO3 TNPO1 TNPO2 | nuclear import signal receptor activity |
| GO:0051170 | 0.00421451513409 | 0.333333333333 | TNPO3 TNPO1 IPO11 HEATR3 TNPO2 | import into nucleus |
| GO:0017038 | 0.0105705464599 | 0.333333333333 | TNPO3 TNPO1 IPO11 HEATR3 TNPO2 | protein import |
| HPA:047030_23 | 0.0155594576332 | 0.266666666667 | TNPO3 TNPO1 SAAL1 CIP2A | soft tissue 1; fibroblasts[Approved,High] |
| GO:0034504 | 0.0390491758704 | 0.333333333333 | TNPO3 TNPO1 IPO11 HEATR3 TNPO2 | protein localization to nucleus |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TNPO1 | FANCD2 | 0.586 | 0.662 | bioplex_WMM boldt youn_WMM fraction boldt_WMM treiber_WMM |
| TNPO1 | ATXN10 | 0.174 | 0.433 | hein_WMM bioplex_WMM boldt youn_WMM hein (TNPO1) gupta_WMM boldt_WMM |
| TNPO1 | TNPO2 | 0.105 | 0.369 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM treiber_WMM |
| VSIG2 | TNPO2 | 0.071 | 0.352 | bioplex (VSIG2) bioplex_WMM |
| SAAL1 | XPO4 | 0.068 | 0.349 | bioplex_WMM boldt boldt_WMM |
| TNPO3 | VSIG2 | 0.05 | 0.297 | bioplex (VSIG2) bioplex_WMM |
| XPO4 | VSIG2 | 0.045 | 0.279 | bioplex (VSIG2) bioplex_WMM |
| XPO6 | VSIG2 | 0.043 | 0.269 | bioplex (VSIG2) bioplex_WMM |
| TNPO1 | VSIG2 | 0.042 | 0.27 | bioplex (VSIG2) bioplex_WMM |
| XPO5 | XPO7 | 0.039 | 0.264 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM treiber_WMM |
| XPO4 | CIP2A | 0.039 | 0.264 | bioplex_WMM boldt boldt_WMM |
| XPO6 | THADA | 0.036 | 0.264 | bioplex_WMM boldt boldt_WMM |
| XPO4 | TNPO2 | 0.033 | 0.248 | bioplex_WMM boldt boldt_WMM |
| SAAL1 | CIP2A | 0.03 | 0.231 | bioplex_WMM boldt boldt_WMM |
| SAAL1 | TNPO3 | 0.029 | 0.233 | bioplex_WMM boldt boldt_WMM |
| XPO4 | TNPO3 | 0.029 | 0.232 | bioplex_WMM boldt boldt_WMM |
| TNPO3 | XPO7 | 0.027 | 0.228 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM treiber_WMM |
| TNPO2 | XPO7 | 0.027 | 0.224 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| XPO6 | CIP2A | 0.027 | 0.223 | bioplex_WMM boldt boldt_WMM |
| TNPO1 | HEATR3 | 0.026 | 0.222 | bioplex_WMM boldt youn_WMM fraction boldt_WMM |
| TNPO1 | CIP2A | 0.026 | 0.22 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| SAAL1 | TNPO2 | 0.024 | 0.216 | bioplex_WMM boldt boldt_WMM |
| FANCD2 | XPO4 | 0.023 | 0.206 | bioplex_WMM boldt boldt_WMM |
| TNPO2 | CIP2A | 0.023 | 0.209 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| CIP2A | THADA | 0.023 | 0.211 | bioplex_WMM boldt youn_WMM boldt_WMM |
| FANCD2 | IPO11 | 0.023 | 0.21 | bioplex_WMM boldt youn_WMM boldt_WMM |
| XPO4 | IPO11 | 0.022 | 0.206 | bioplex_WMM boldt boldt_WMM |
| XPO4 | THADA | 0.022 | 0.209 | bioplex_WMM boldt boldt_WMM |
| XPO5 | THADA | 0.022 | 0.207 | bioplex_WMM boldt youn_WMM boldt_WMM treiber_WMM |
| CIP2A | XPO7 | 0.022 | 0.199 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| TNPO1 | SAAL1 | 0.022 | 0.195 | bioplex_WMM boldt boldt_WMM |
| TNPO3 | XPO5 | 0.022 | 0.195 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM treiber_WMM |
| TNPO1 | XPO4 | 0.021 | 0.194 | bioplex_WMM boldt boldt_WMM |
| XPO6 | TNPO2 | 0.021 | 0.188 | bioplex_WMM boldt boldt_WMM |
| ATXN10 | IPO11 | 0.02 | 0.187 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| SAAL1 | HEATR3 | 0.02 | 0.185 | bioplex_WMM boldt boldt_WMM |
| TNPO3 | THADA | 0.02 | 0.184 | bioplex_WMM boldt youn_WMM boldt_WMM |
| TNPO1 | XPO5 | 0.02 | 0.185 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM treiber_WMM |
| XPO6 | XPO5 | 0.02 | 0.187 | bioplex_WMM boldt boldt_WMM |
| XPO6 | TNPO3 | 0.019 | 0.183 | bioplex_WMM boldt boldt_WMM |
| XPO4 | XPO6 | 0.019 | 0.188 | bioplex_WMM boldt boldt_WMM |
| FANCD2 | CIP2A | 0.018 | 0.18 | bioplex_WMM boldt youn_WMM boldt_WMM |
| TNPO2 | IPO11 | 0.018 | 0.177 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| TNPO3 | CIP2A | 0.018 | 0.178 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| XPO7 | THADA | 0.018 | 0.177 | bioplex_WMM boldt youn_WMM boldt_WMM |
| XPO4 | XPO7 | 0.017 | 0.174 | bioplex_WMM boldt boldt_WMM |
| TNPO1 | XPO6 | 0.017 | 0.173 | bioplex_WMM boldt boldt_WMM |
| TNPO2 | THADA | 0.017 | 0.176 | bioplex_WMM boldt youn_WMM boldt_WMM |
| SAAL1 | IPO11 | 0.017 | 0.17 | bioplex_WMM boldt boldt_WMM |
| XPO5 | CIP2A | 0.017 | 0.167 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| TNPO2 | XPO5 | 0.016 | 0.165 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM treiber_WMM |
| TNPO1 | IPO11 | 0.016 | 0.165 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM treiber_WMM |
| XPO4 | HEATR3 | 0.016 | 0.159 | bioplex_WMM boldt boldt_WMM |
| CIP2A | IPO11 | 0.016 | 0.156 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| IPO11 | XPO7 | 0.016 | 0.154 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM treiber_WMM |
| ATXN10 | XPO4 | 0.015 | 0.14 | bioplex_WMM boldt boldt_WMM |
| CIP2A | HEATR3 | 0.014 | 0.14 | bioplex_WMM boldt boldt_WMM |
| ATXN10 | CIP2A | 0.014 | 0.137 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| TNPO3 | HEATR3 | 0.014 | 0.139 | bioplex_WMM boldt youn_WMM boldt_WMM |
| TNPO1 | TNPO3 | 0.013 | 0.151 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| SAAL1 | XPO7 | 0.013 | 0.151 | bioplex_WMM boldt boldt_WMM |
| IPO11 | HEATR3 | 0.013 | 0.153 | bioplex_WMM boldt youn_WMM boldt_WMM |
| XPO6 | IPO11 | 0.013 | 0.154 | bioplex_WMM boldt boldt_WMM |
| IPO11 | THADA | 0.013 | 0.15 | bioplex_WMM boldt youn_WMM boldt_WMM |
| VSIG2 | XPO5 | 0.012 | 0.147 | bioplex (VSIG2) bioplex_WMM |
| ATXN10 | SAAL1 | 0.012 | 0.151 | bioplex_WMM boldt boldt_WMM |
| XPO5 | IPO11 | 0.012 | 0.151 | youn (IPO11) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM treiber_WMM |
| FANCD2 | SAAL1 | 0.011 | 0.15 | bioplex_WMM boldt boldt_WMM |
| ATXN10 | HEATR3 | 0.011 | 0.148 | bioplex_WMM boldt youn_WMM boldt_WMM |
| XPO4 | XPO5 | 0.011 | 0.143 | bioplex_WMM boldt boldt_WMM |
| TNPO1 | XPO7 | 0.011 | 0.143 | bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| TNPO1 | THADA | 0.011 | 0.142 | bioplex_WMM boldt youn_WMM boldt_WMM |
| FANCD2 | XPO7 | 0.011 | 0.141 | bioplex_WMM boldt youn_WMM boldt_WMM |
| SAAL1 | THADA | 0.011 | 0.141 | bioplex_WMM boldt boldt_WMM |
| SAAL1 | XPO6 | 0.011 | 0.142 | bioplex_WMM boldt boldt_WMM |
| FANCD2 | XPO5 | 0.01 | 0.139 | bioplex_WMM boldt youn_WMM boldt_WMM treiber_WMM |
| FANCD2 | XPO6 | 0.01 | 0.132 | bioplex_WMM boldt boldt_WMM |
| TNPO2 | HEATR3 | 0.01 | 0.134 | bioplex_WMM boldt boldt_WMM |
| SAAL1 | XPO5 | 0.01 | 0.134 | bioplex_WMM boldt gupta_WMM boldt_WMM |
| TNPO3 | TNPO2 | 0.01 | 0.13 | bioplex_WMM boldt youn_WMM fraction boldt_WMM |
| FANCD2 | THADA | 0.01 | 0.127 | bioplex_WMM boldt youn_WMM boldt_WMM treiber_WMM |
| SAAL1 | VSIG2 | 0.01 | 0.12 | bioplex (VSIG2) bioplex_WMM |
| TNPO3 | IPO11 | 0.01 | 0.106 | youn (IPO11) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM treiber_WMM |
| ATXN10 | TNPO2 | 0.01 | 0.1 | bioplex_WMM boldt youn_WMM boldt_WMM |
| FANCD2 | HEATR3 | 0.009 | 0.113 | hein_WMM bioplex_WMM boldt youn_WMM boldt_WMM |
| XPO7 | HEATR3 | 0.009 | 0.107 | bioplex_WMM boldt youn_WMM boldt_WMM |
| ATXN10 | XPO6 | 0.009 | 0.109 | bioplex_WMM boldt boldt_WMM |
| ATXN10 | FANCD2 | 0.009 | 0.108 | bioplex_WMM boldt youn_WMM boldt_WMM |
| ATXN10 | XPO5 | 0.009 | 0.107 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| XPO6 | HEATR3 | 0.009 | 0.1 | bioplex_WMM boldt boldt_WMM |
| ATXN10 | TNPO3 | 0.009 | 0.099 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| ATXN10 | THADA | 0.009 | 0.097 | bioplex_WMM boldt youn_WMM boldt_WMM |
| HEATR3 | THADA | 0.008 | 0.087 | bioplex_WMM boldt boldt_WMM |
| ATXN10 | XPO7 | 0.008 | 0.088 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| XPO5 | HEATR3 | 0.008 | 0.065 | bioplex_WMM boldt youn_WMM boldt_WMM |
| FANCD2 | TNPO2 | 0.008 | 0.037 | bioplex_WMM boldt youn_WMM fraction boldt_WMM |
| XPO6 | XPO7 | 0.007 | 0.004 | bioplex_WMM boldt fraction boldt_WMM |
| FANCD2 | TNPO3 | 0.006 | 0.008 | bioplex_WMM boldt youn_WMM fraction boldt_WMM |
| ATXN10 | VSIG2 | 0.005 | 0.011 | bioplex (VSIG2) bioplex_WMM |
| VSIG2 | THADA | 0.004 | 0.014 | bioplex (VSIG2) bioplex_WMM |
| FANCD2 | VSIG2 | 0.003 | 0.014 | bioplex (VSIG2) bioplex_WMM |
| VSIG2 | CIP2A | 0.0 | 0.011 | bioplex (VSIG2) bioplex_WMM |
| VSIG2 | XPO7 | 0.0 | 0.011 | bioplex (VSIG2) bioplex_WMM |
Images
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Complex HuMAP2_03084 has an average edge precision of 0.172 which is ranked 6510 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| VSIG2 | HuMAP2_01794 HuMAP2_03084 HuMAP2_06562 HuMAP2_06809 |
| TNPO1 | HuMAP2_00442 HuMAP2_03084 HuMAP2_03089 HuMAP2_06562 |
| XPO6 | HuMAP2_01794 HuMAP2_03084 HuMAP2_06562 HuMAP2_06809 |
| XPO7 | HuMAP2_03084 HuMAP2_05243 HuMAP2_06562 |
| XPO5 | HuMAP2_02331 HuMAP2_03084 HuMAP2_06562 |
| THADA | HuMAP2_03084 HuMAP2_06562 |
| TNPO3 | HuMAP2_01794 HuMAP2_03084 HuMAP2_03408 HuMAP2_06562 |
| CIP2A | HuMAP2_03084 HuMAP2_03525 HuMAP2_05972 HuMAP2_06562 |
| IPO11 | HuMAP2_03084 HuMAP2_06562 |
| ATXN10 | HuMAP2_00442 HuMAP2_03084 HuMAP2_03966 HuMAP2_06390 HuMAP2_06562 |
| FANCD2 | HuMAP2_00442 HuMAP2_03084 HuMAP2_03089 HuMAP2_03715 HuMAP2_03950 HuMAP2_06562 |
| XPO4 | HuMAP2_00813 HuMAP2_03084 HuMAP2_06562 HuMAP2_06809 |
| SAAL1 | HuMAP2_00813 HuMAP2_03084 HuMAP2_06562 |
| TNPO2 | HuMAP2_01904 HuMAP2_03084 HuMAP2_06562 |
| HEATR3 | HuMAP2_03084 HuMAP2_06562 |