hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03109
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PDXP | Pyridoxal phosphate phosphatase (PLP phosphatase) (EC 3.1.3.3) (EC 3.1.3.74) (Chronophin) | UniProt NCBI |
| RAE1 | mRNA export factor (Rae1 protein homolog) (mRNA-associated protein mrnp 41) | UniProt NCBI |
| ALDOA | Fructose-bisphosphate aldolase A (EC 4.1.2.13) (Lung cancer antigen NY-LU-1) (Muscle-type aldolase) | UniProt NCBI |
| ALDOC | Fructose-bisphosphate aldolase C (EC 4.1.2.13) (Brain-type aldolase) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-70171 | 6.16010596593e-05 | 0.75 | RAE1 ALDOA ALDOC | Glycolysis |
| REAC:R-HSA-70326 | 0.000119121057505 | 0.75 | RAE1 ALDOA ALDOC | Glucose metabolism |
| KEGG:00030 | 0.000811520562786 | 0.5 | ALDOC ALDOA | Pentose phosphate pathway |
| KEGG:00051 | 0.00105499815766 | 0.5 | ALDOC ALDOA | Fructose and mannose metabolism |
| WP:WP534 | 0.0015833920549 | 0.5 | ALDOC ALDOA | Glycolysis and Gluconeogenesis |
| KEGG:00010 | 0.00389180767222 | 0.5 | ALDOC ALDOA | Glycolysis / Gluconeogenesis |
| REAC:R-HSA-71387 | 0.00394951473773 | 0.75 | RAE1 ALDOA ALDOC | Metabolism of carbohydrates |
| REAC:R-HSA-70263 | 0.00436320194063 | 0.5 | ALDOC ALDOA | Gluconeogenesis |
| KEGG:01230 | 0.00494838688052 | 0.5 | ALDOC ALDOA | Biosynthesis of amino acids |
| WP:WP4018 | 0.00527207105384 | 0.5 | ALDOC ALDOA | Pathways in clear cell renal cell carcinoma |
| GO:0004332 | 0.00811409485621 | 0.5 | ALDOC ALDOA | fructose-bisphosphate aldolase activity |
| KEGG:04066 | 0.00983130325145 | 0.5 | ALDOC ALDOA | HIF-1 signaling pathway |
| KEGG:01200 | 0.012776519361 | 0.5 | ALDOC ALDOA | Carbon metabolism |
| MIRNA:hsa-miR-454-5p | 0.0232347082803 | 0.5 | ALDOC ALDOA | hsa-miR-454-5p |
| GO:0006096 | 0.0469269676219 | 0.75 | RAE1 ALDOA ALDOC | glycolytic process |
| GO:0006757 | 0.0484715579516 | 0.75 | RAE1 ALDOA ALDOC | ATP generation from ADP |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ALDOC | RAE1 | 0.975 | 0.887 | bioplex_WMM fraction |
| ALDOA | ALDOC | 0.937 | 0.85 | hein_WMM bioplex (ALDOA,ALDOC) bioplex_WMM hein (ALDOA) fraction treiber_WMM |
| ALDOA | RAE1 | 0.228 | 0.468 | bioplex (RAE1) bioplex_WMM boldt fraction boldt_WMM treiber_WMM |
| PDXP | ALDOA | 0.084 | 0.349 | bioplex_WMM fraction |
| PDXP | ALDOC | 0.068 | 0.35 | fraction |
| PDXP | RAE1 | 0.0 | 0.009 | youn_WMM fraction |
Images
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Complex HuMAP2_03109 has an average edge precision of 0.485 which is ranked 2589 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PDXP | HuMAP2_01418 HuMAP2_02116 HuMAP2_03109 HuMAP2_06138 |
| RAE1 | HuMAP2_03109 HuMAP2_04230 HuMAP2_04680 HuMAP2_05544 |
| ALDOA | HuMAP2_01418 HuMAP2_01883 HuMAP2_03109 HuMAP2_04680 HuMAP2_06632 HuMAP2_06652 |
| ALDOC | HuMAP2_01418 HuMAP2_03109 HuMAP2_04230 HuMAP2_04680 HuMAP2_06764 |