hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03133
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PDGFC | Platelet-derived growth factor C (PDGF-C) (Fallotein) (Spinal cord-derived growth factor) (SCDGF) (VEGF-E) [Cleaved into: Platelet-derived growth factor C, latent form (PDGFC latent form); Platelet-derived growth factor C, receptor-binding form (PDGFC receptor-binding form)] | UniProt NCBI |
| CREB3 | Cyclic AMP-responsive element-binding protein 3 (CREB-3) (cAMP-responsive element-binding protein 3) (Leucine zipper protein) (Luman) (Transcription factor LZIP-alpha) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3 (N-terminal Luman) (Transcriptionally active form)] | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:05215 | 0.000584319664263 | 1.0 | CREB3 PDGFC | Prostate cancer |
| KEGG:04151 | 0.00654350485448 | 1.0 | CREB3 PDGFC | PI3K-Akt signaling pathway |
| WP:WP3932 | 0.0121610546673 | 1.0 | CREB3 PDGFC | Focal Adhesion-PI3K-Akt-mTOR-signaling pathway |
| WP:WP4172 | 0.015291110435 | 1.0 | CREB3 PDGFC | PI3K-Akt Signaling Pathway |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CREB3 | PDGFC | 0.277 | 0.485 | bioplex (CREB3) bioplex_WMM |
Images
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Complex HuMAP2_03133 has an average edge precision of 0.485 which is ranked 2593 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PDGFC | HuMAP2_03133 HuMAP2_03462 HuMAP2_03732 HuMAP2_06679 |
| CREB3 | HuMAP2_03133 HuMAP2_03462 HuMAP2_03732 HuMAP2_06679 |