hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03134
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PDIA6 | Protein disulfide-isomerase A6 (EC 5.3.4.1) (Endoplasmic reticulum protein 5) (ER protein 5) (ERp5) (Protein disulfide isomerase P5) (Thioredoxin domain-containing protein 7) | UniProt NCBI |
| HYOU1 | Hypoxia up-regulated protein 1 (150 kDa oxygen-regulated protein) (ORP-150) (170 kDa glucose-regulated protein) (GRP-170) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-381038 | 0.00158542359541 | 1.0 | HYOU1 PDIA6 | XBP1(S) activates chaperone genes |
| REAC:R-HSA-381070 | 0.00173458078356 | 1.0 | HYOU1 PDIA6 | IRE1alpha activates chaperones |
| KEGG:04141 | 0.00178666132548 | 1.0 | HYOU1 PDIA6 | Protein processing in endoplasmic reticulum |
| GO:0034663 | 0.00450823411379 | 1.0 | HYOU1 PDIA6 | endoplasmic reticulum chaperone complex |
| REAC:R-HSA-381119 | 0.00570316754246 | 1.0 | HYOU1 PDIA6 | Unfolded Protein Response (UPR) |
| HP:0020098 | 0.0497341708567 | 0.5 | HYOU1 | Herpes encephalitis |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PDIA6 | HYOU1 | 0.971 | 0.883 | bioplex (PDIA6) bioplex_WMM Guru youn_WMM gupta_WMM fraction treiber_WMM |
Images
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Complex HuMAP2_03134 has an average edge precision of 0.883 which is ranked 646 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PDIA6 | HuMAP2_01369 HuMAP2_01492 HuMAP2_03134 |
| HYOU1 | HuMAP2_01492 HuMAP2_03134 |