hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03138
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ASF1A | Histone chaperone ASF1A (Anti-silencing function protein 1 homolog A) (hAsf1) (hAsf1a) (CCG1-interacting factor A) (CIA) (hCIA) | UniProt NCBI |
| CDAN1 | Codanin-1 | UniProt NCBI |
| CABIN1 | Calcineurin-binding protein cabin-1 (Calcineurin inhibitor) (CAIN) | UniProt NCBI |
| UBN2 | Ubinuclein-2 | UniProt NCBI |
| UBN1 | Ubinuclein-1 (HIRA-binding protein) (Protein VT4) (Ubiquitously expressed nuclear protein) | UniProt NCBI |
| C15orf41 | Uncharacterized protein C15orf41 (Protein HH114) | UniProt NCBI |
| ASF1B | Histone chaperone ASF1B (Anti-silencing function protein 1 homolog B) (hAsf1) (hAsf1b) (CCG1-interacting factor A-II) (CIA-II) (hCIA-II) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-2559584 | 5.93774784282e-06 | 0.428571428571 | ASF1A CABIN1 UBN1 | Formation of Senescence-Associated Heterochromatin Foci (SAHF) |
| CORUM:6149 | 3.02079974644e-05 | 0.285714285714 | ASF1A CDAN1 | Codanin-1-Asf1-histone H3.1-histone H4-importin-4 complex, cytosolic |
| CORUM:7383 | 6.04024714829e-05 | 0.285714285714 | UBN1 CABIN1 | OGT-HIRA complex |
| CORUM:7382 | 6.04024714829e-05 | 0.285714285714 | UBN1 CABIN1 | Prohibitin-HIRA complex |
| GO:0031497 | 6.33189048071e-05 | 0.714285714286 | ASF1A UBN1 ASF1B CDAN1 CABIN1 | chromatin assembly |
| CORUM:2235 | 0.000100648251269 | 0.285714285714 | ASF1A ASF1B | ASF1-interacting protein complex |
| GO:0006333 | 0.000122057615532 | 0.714285714286 | ASF1A UBN1 ASF1B CDAN1 CABIN1 | chromatin assembly or disassembly |
| CORUM:2236 | 0.000150938581911 | 0.285714285714 | ASF1A ASF1B | ASF1-histone containing complex |
| GO:0006323 | 0.000188293700604 | 0.714285714286 | ASF1A UBN1 ASF1B CDAN1 CABIN1 | DNA packaging |
| CORUM:1150 | 0.000211266711219 | 0.285714285714 | ASF1A ASF1B | Histone H3.3 complex |
| GO:0006336 | 0.000267858993773 | 0.571428571429 | ASF1A ASF1B CABIN1 UBN1 | DNA replication-independent nucleosome assembly |
| CORUM:1149 | 0.000281625889725 | 0.285714285714 | ASF1A ASF1B | Histone H3.1 complex |
| GO:0034724 | 0.000288820867155 | 0.571428571429 | ASF1A ASF1B CABIN1 UBN1 | DNA replication-independent nucleosome organization |
| REAC:R-HSA-2559586 | 0.000827889523177 | 0.428571428571 | ASF1A CABIN1 UBN1 | DNA Damage/Telomere Stress Induced Senescence |
| GO:0071103 | 0.000938903144903 | 0.714285714286 | ASF1A UBN1 ASF1B CDAN1 CABIN1 | DNA conformation change |
| HP:0012132 | 0.00322839434563 | 0.285714285714 | C15orf41 CDAN1 | Erythroid hyperplasia |
| GO:0006334 | 0.00449957152016 | 0.571428571429 | ASF1A ASF1B CABIN1 UBN1 | nucleosome assembly |
| HP:0011273 | 0.00898332183607 | 0.285714285714 | C15orf41 CDAN1 | Anisocytosis |
| HP:0012131 | 0.0104781956652 | 0.285714285714 | C15orf41 CDAN1 | Abnormal number of erythroid precursors |
| REAC:R-HSA-2559583 | 0.0111605185078 | 0.428571428571 | ASF1A CABIN1 UBN1 | Cellular Senescence |
| GO:0034728 | 0.0178183346517 | 0.571428571429 | ASF1A ASF1B CABIN1 UBN1 | nucleosome organization |
| GO:0065004 | 0.0426708894575 | 0.571428571429 | ASF1A ASF1B CABIN1 UBN1 | protein-DNA complex assembly |
| CORUM:5189 | 0.0499886427319 | 0.142857142857 | CABIN1 | YWHAQ-CALM1-CABIN1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ASF1A | CDAN1 | 1.0 | 0.949 | hein_WMM bioplex (ASF1A) bioplex_WMM hein (ASF1A) |
| ASF1A | C15orf41 | 0.999 | 0.945 | hein_WMM bioplex (ASF1A) bioplex_WMM hein (ASF1A) |
| ASF1A | UBN1 | 0.973 | 0.886 | hein_WMM bioplex (ASF1A) bioplex_WMM hein (ASF1A) |
| ASF1A | UBN2 | 0.96 | 0.866 | hein_WMM bioplex (ASF1A) bioplex_WMM youn_WMM hein (ASF1A) |
| ASF1A | CABIN1 | 0.948 | 0.856 | hein_WMM bioplex (ASF1A) bioplex_WMM hein (ASF1A) |
| CDAN1 | ASF1B | 0.941 | 0.854 | hein_WMM bioplex (ASF1B) bioplex_WMM |
| UBN1 | ASF1B | 0.897 | 0.822 | hein_WMM bioplex (ASF1B) bioplex_WMM youn_WMM |
| ASF1B | C15orf41 | 0.809 | 0.769 | hein_WMM bioplex (ASF1B) bioplex_WMM |
| CABIN1 | ASF1B | 0.773 | 0.751 | hein_WMM bioplex (ASF1B) bioplex_WMM |
| ASF1B | UBN2 | 0.738 | 0.738 | hein_WMM bioplex (ASF1B) bioplex_WMM youn_WMM |
| ASF1A | ASF1B | 0.015 | 0.151 | hein_WMM bioplex (ASF1A,ASF1B) bioplex_WMM youn_WMM hein (ASF1A) |
| CABIN1 | UBN2 | 0.014 | 0.137 | hein_WMM bioplex_WMM WMM_only |
| CDAN1 | C15orf41 | 0.013 | 0.154 | hein_WMM bioplex_WMM WMM_only |
| UBN1 | UBN2 | 0.013 | 0.151 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| CDAN1 | UBN1 | 0.012 | 0.149 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| UBN1 | C15orf41 | 0.012 | 0.147 | hein_WMM bioplex_WMM WMM_only |
| CDAN1 | CABIN1 | 0.011 | 0.144 | hein_WMM bioplex_WMM WMM_only |
| CABIN1 | C15orf41 | 0.011 | 0.143 | hein_WMM bioplex_WMM WMM_only |
| CDAN1 | UBN2 | 0.011 | 0.137 | hein_WMM bioplex_WMM WMM_only |
| C15orf41 | UBN2 | 0.011 | 0.134 | hein_WMM bioplex_WMM WMM_only |
| CABIN1 | UBN1 | 0.011 | 0.142 | hein_WMM bioplex_WMM WMM_only |
Images
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Complex HuMAP2_03138 has an average edge precision of 0.477 which is ranked 2653 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ASF1A | HuMAP2_01017 HuMAP2_03138 |
| CDAN1 | HuMAP2_01017 HuMAP2_03138 |
| CABIN1 | HuMAP2_01017 HuMAP2_02693 HuMAP2_03138 HuMAP2_05099 |
| UBN2 | HuMAP2_01017 HuMAP2_03138 |
| UBN1 | HuMAP2_01017 HuMAP2_03138 |
| C15orf41 | HuMAP2_01017 HuMAP2_03138 |
| ASF1B | HuMAP2_01017 HuMAP2_03138 |