hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03140
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| TPX2 | Targeting protein for Xklp2 (Differentially expressed in cancerous and non-cancerous lung cells 2) (DIL-2) (Hepatocellular carcinoma-associated antigen 519) (Hepatocellular carcinoma-associated antigen 90) (Protein fls353) (Restricted expression proliferation-associated protein 100) (p100) | UniProt NCBI |
| INVS | Inversin (Inversion of embryo turning homolog) (Nephrocystin-2) | UniProt NCBI |
| AFAP1 | Actin filament-associated protein 1 (110 kDa actin filament-associated protein) (AFAP-110) | UniProt NCBI |
| EXT2 | Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 2) (Putative tumor suppressor protein EXT2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6881 | 0.0499140284799 | 0.25 | EXT2 | EXT1-EXT2 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| EXT2 | AFAP1 | 0.323 | 0.511 | bioplex (EXT2) bioplex_WMM |
| INVS | EXT2 | 0.094 | 0.357 | bioplex (EXT2) bioplex_WMM |
| AFAP1 | TPX2 | 0.023 | 0.206 | hein_WMM hein (TPX2) |
| INVS | AFAP1 | 0.009 | 0.095 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_03140 has an average edge precision of 0.292 which is ranked 4722 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| TPX2 | HuMAP2_03140 HuMAP2_05570 |
| INVS | HuMAP2_02193 HuMAP2_03140 HuMAP2_03988 |
| AFAP1 | HuMAP2_02193 HuMAP2_03140 |
| EXT2 | HuMAP2_02193 HuMAP2_03140 HuMAP2_03988 |