hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_03142
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ATF6B | Cyclic AMP-dependent transcription factor ATF-6 beta (cAMP-dependent transcription factor ATF-6 beta) (Activating transcription factor 6 beta) (ATF6-beta) (Protein G13) (cAMP response element-binding protein-related protein) (Creb-rp) (cAMP-responsive element-binding protein-like 1) [Cleaved into: Processed cyclic AMP-dependent transcription factor ATF-6 beta] | UniProt NCBI |
| SERPINC1 | Antithrombin-III (ATIII) (Serpin C1) | UniProt NCBI |
| TEX15 | NCBI | |
| BTD | Biotinidase (Biotinase) (EC 3.5.1.12) | UniProt NCBI |
| CAPN11 | Calpain-11 (EC 3.4.22.-) (Calcium-activated neutral proteinase 11) (CANP 11) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00780 | 0.0298344918043 | 0.25 | BTD | Biotin metabolism |
| REAC:R-HSA-3371598 | 0.0499190562503 | 0.25 | BTD | Defective BTD causes biotidinase deficiency |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TEX15 | SERPINC1 | 0.041 | 0.269 | bioplex (SERPINC1) bioplex_WMM |
| CAPN11 | SERPINC1 | 0.037 | 0.266 | fraction |
| BTD | SERPINC1 | 0.029 | 0.234 | bioplex (SERPINC1) bioplex_WMM |
| TEX15 | ATF6B | 0.02 | 0.187 | bioplex (ATF6B) bioplex_WMM |
| TEX15 | BTD | 0.007 | 0.01 | bioplex_WMM WMM_only |
| BTD | ATF6B | 0.007 | 0.005 | bioplex_WMM WMM_only |
Images
Click to enlarge
Complex HuMAP2_03142 has an average edge precision of 0.162 which is ranked 6609 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ATF6B | HuMAP2_01120 HuMAP2_01294 HuMAP2_03142 |
| SERPINC1 | HuMAP2_01120 HuMAP2_01821 HuMAP2_03142 HuMAP2_06491 |
| TEX15 | HuMAP2_01120 HuMAP2_01294 HuMAP2_01821 HuMAP2_03142 HuMAP2_06491 |
| BTD | HuMAP2_01120 HuMAP2_03142 |
| CAPN11 | HuMAP2_01066 HuMAP2_03142 HuMAP2_06283 |