hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03148
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CTNND1 | Catenin delta-1 (Cadherin-associated Src substrate) (CAS) (p120 catenin) (p120(ctn)) (p120(cas)) | UniProt NCBI |
| CDH8 | Cadherin-8 | UniProt NCBI |
| CDH11 | Cadherin-11 (OSF-4) (Osteoblast cadherin) (OB-cadherin) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-418990 | 1.31507096469e-06 | 1.0 | CDH8 CTNND1 CDH11 | Adherens junctions interactions |
| REAC:R-HSA-421270 | 5.95446148936e-06 | 1.0 | CDH8 CTNND1 CDH11 | Cell-cell junction organization |
| CORUM:6337 | 2.01342304124e-05 | 0.666666666667 | CTNND1 CDH11 | Amot-cadherin-11-beta-catenin-p120 complex |
| REAC:R-HSA-446728 | 2.56967114485e-05 | 1.0 | CDH8 CTNND1 CDH11 | Cell junction organization |
| REAC:R-HSA-1500931 | 7.95116633082e-05 | 1.0 | CDH8 CTNND1 CDH11 | Cell-Cell communication |
| GO:0016342 | 0.000139860607076 | 1.0 | CDH8 CTNND1 CDH11 | catenin complex |
| GO:0044331 | 0.000594407580071 | 1.0 | CDH8 CTNND1 CDH11 | cell-cell adhesion mediated by cadherin |
| HP:0100338 | 0.000803978270478 | 0.666666666667 | CTNND1 CDH11 | Non-midline cleft palate |
| WP:WP4540 | 0.00357470816736 | 0.666666666667 | CDH8 CDH11 | Pathways Regulating Hippo Signaling |
| WP:WP4541 | 0.00491871423903 | 0.666666666667 | CDH8 CDH11 | Hippo-Merlin Signaling Dysregulation |
| GO:0005913 | 0.0103137207675 | 1.0 | CDH8 CTNND1 CDH11 | cell-cell adherens junction |
| GO:0007043 | 0.0110330947082 | 1.0 | CDH8 CTNND1 CDH11 | cell-cell junction assembly |
| GO:0034332 | 0.0185411572066 | 1.0 | CDH8 CTNND1 CDH11 | adherens junction organization |
| GO:0045216 | 0.0196004650773 | 1.0 | CDH8 CTNND1 CDH11 | cell-cell junction organization |
| HP:0012368 | 0.0237990042853 | 0.666666666667 | CTNND1 CDH11 | Flat face |
| CORUM:6599 | 0.0249904952816 | 0.333333333333 | CTNND1 | CTNND1-GLIS2 complex |
| GO:0019897 | 0.0281650200706 | 1.0 | CDH8 CTNND1 CDH11 | extrinsic component of plasma membrane |
| HP:0000324 | 0.0462248590062 | 0.666666666667 | CTNND1 CDH11 | Facial asymmetry |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CDH8 | CDH11 | 0.962 | 0.87 | bioplex (CDH8) bioplex_WMM |
| CDH8 | CTNND1 | 0.092 | 0.356 | bioplex (CDH8) bioplex_WMM |
| CDH11 | CTNND1 | 0.007 | 0.005 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_03148 has an average edge precision of 0.41 which is ranked 3194 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CTNND1 | HuMAP2_01324 HuMAP2_01826 HuMAP2_02710 HuMAP2_03148 HuMAP2_04808 HuMAP2_05814 |
| CDH8 | HuMAP2_00784 HuMAP2_01438 HuMAP2_03148 HuMAP2_04808 HuMAP2_05814 |
| CDH11 | HuMAP2_00784 HuMAP2_01438 HuMAP2_03148 HuMAP2_04808 HuMAP2_05814 |