hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03152
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| GPAT3 | Glycerol-3-phosphate acyltransferase 3 (GPAT-3) (EC 2.3.1.15) (1-acyl-sn-glycerol-3-phosphate O-acyltransferase 10) (AGPAT 10) (1-acyl-sn-glycerol-3-phosphate O-acyltransferase 9) (1-AGP acyltransferase 9) (1-AGPAT 9) (EC 2.3.1.51) (Acyl-CoA:glycerol-3-phosphate acyltransferase 3) (hGPAT3) (Lung cancer metastasis-associated protein 1) (Lysophosphatidic acid acyltransferase theta) (LPAAT-theta) (MAG-1) | UniProt NCBI |
| SLC6A15 | Sodium-dependent neutral amino acid transporter B(0)AT2 (Sodium- and chloride-dependent neurotransmitter transporter NTT73) (Sodium-coupled branched-chain amino-acid transporter 1) (Solute carrier family 6 member 15) (Transporter v7-3) | UniProt NCBI |
| GPAT4 | Glycerol-3-phosphate acyltransferase 4 (EC 2.3.1.15) (1-acylglycerol-3-phosphate O-acyltransferase 6) (1-AGP acyltransferase 6) (1-AGPAT 6) (Acyl-CoA:glycerol-3-phosphate acyltransferase 4) (Lysophosphatidic acid acyltransferase zeta) (LPAAT-zeta) (Testis spermatogenesis apoptosis-related protein 7) (TSARG7) | UniProt NCBI |
| TEX2 | Testis-expressed protein 2 (Transmembrane protein 96) | UniProt NCBI |
| CHP1 | Calcineurin B homologous protein 1 (Calcineurin B-like protein) (Calcium-binding protein CHP) (Calcium-binding protein p22) (EF-hand calcium-binding domain-containing protein p22) | UniProt NCBI |
| HACD2 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase 2) (HACD2) (Protein-tyrosine phosphatase-like member B) | UniProt NCBI |
| AUP1 | Ancient ubiquitous protein 1 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:007030_22 | 0.00132617113595 | 0.857142857143 | TEX2 CHP1 AUP1 GPAT4 HACD2 GPAT3 | cerebellum; cells in molecular layer[Approved,Medium] |
| HPA:022020_22 | 0.0122809414898 | 0.857142857143 | TEX2 CHP1 AUP1 GPAT4 HACD2 GPAT3 | hippocampus; neuronal cells[Approved,Medium] |
| KEGG:00561 | 0.0145629093746 | 0.285714285714 | GPAT4 GPAT3 | Glycerolipid metabolism |
| REAC:R-HSA-1483166 | 0.0146280770201 | 0.285714285714 | GPAT4 GPAT3 | Synthesis of PA |
| HPA:021010_22 | 0.0200354658987 | 0.857142857143 | TEX2 CHP1 AUP1 GPAT4 HACD2 GPAT3 | heart muscle; myocytes[Approved,Medium] |
| HPA:007010_22 | 0.0260999706054 | 0.857142857143 | TEX2 CHP1 AUP1 GPAT4 HACD2 GPAT3 | cerebellum; Purkinje cells[Approved,Medium] |
| HPA:008020_21 | 0.0266464197836 | 0.857142857143 | TEX2 CHP1 AUP1 GPAT4 HACD2 GPAT3 | cerebral cortex; glial cells[Approved,Low] |
| HPA:007030_21 | 0.0290585060831 | 0.857142857143 | TEX2 CHP1 AUP1 GPAT4 HACD2 GPAT3 | cerebellum; cells in molecular layer[Approved,Low] |
| KEGG:00564 | 0.030052232514 | 0.285714285714 | GPAT4 GPAT3 | Glycerophospholipid metabolism |
| HPA:008030_22 | 0.0354170459377 | 0.857142857143 | TEX2 CHP1 AUP1 GPAT4 HACD2 GPAT3 | cerebral cortex; neuronal cells[Approved,Medium] |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CHP1 | GPAT4 | 0.742 | 0.74 | bioplex (GPAT4) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| SLC6A15 | GPAT3 | 0.232 | 0.47 | bioplex (SLC6A15) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| GPAT4 | GPAT3 | 0.142 | 0.406 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| TEX2 | SLC6A15 | 0.063 | 0.348 | bioplex (SLC6A15) bioplex_WMM youn_WMM gupta_WMM |
| CHP1 | AUP1 | 0.059 | 0.328 | bioplex (AUP1) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| SLC6A15 | GPAT4 | 0.058 | 0.325 | bioplex (GPAT4,SLC6A15) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| AUP1 | GPAT4 | 0.058 | 0.325 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| HACD2 | SLC6A15 | 0.045 | 0.282 | bioplex (SLC6A15) bioplex_WMM boldt gupta_WMM boldt_WMM |
| SLC6A15 | CHP1 | 0.044 | 0.279 | bioplex (SLC6A15) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| AUP1 | GPAT3 | 0.033 | 0.254 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| CHP1 | GPAT3 | 0.023 | 0.211 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| HACD2 | GPAT4 | 0.02 | 0.186 | bioplex_WMM boldt gupta_WMM boldt_WMM |
| HACD2 | AUP1 | 0.017 | 0.163 | bioplex_WMM boldt gupta_WMM boldt_WMM |
| HACD2 | CHP1 | 0.013 | 0.144 | bioplex_WMM boldt gupta_WMM boldt_WMM |
| HACD2 | GPAT3 | 0.011 | 0.143 | bioplex_WMM gupta_WMM WMM_only boldt_WMM |
| SLC6A15 | AUP1 | 0.01 | 0.132 | bioplex (AUP1,SLC6A15) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| TEX2 | AUP1 | 0.007 | 0.002 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| TEX2 | GPAT3 | 0.007 | 0.005 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| TEX2 | GPAT4 | 0.007 | 0.004 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| TEX2 | CHP1 | 0.007 | 0.004 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| HACD2 | TEX2 | 0.007 | 0.005 | bioplex_WMM gupta_WMM WMM_only |
Images
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Complex HuMAP2_03152 has an average edge precision of 0.226 which is ranked 5754 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| GPAT3 | HuMAP2_03152 HuMAP2_05342 |
| SLC6A15 | HuMAP2_03152 HuMAP2_05342 |
| GPAT4 | HuMAP2_03152 HuMAP2_03641 HuMAP2_05342 |
| TEX2 | HuMAP2_03152 HuMAP2_04523 HuMAP2_05342 |
| CHP1 | HuMAP2_03152 HuMAP2_03641 HuMAP2_05342 |
| HACD2 | HuMAP2_01441 HuMAP2_03152 HuMAP2_05342 |
| AUP1 | HuMAP2_03152 HuMAP2_05342 |