hu.MAP 2.0: Complex View

Human Protein Complex Map

Genename	Protein Name	Links
REEP2	Receptor expression-enhancing protein 2	UniProt NCBI
REEP1	Receptor expression-enhancing protein 1 (Spastic paraplegia 31 protein)	UniProt NCBI
REEP4	Receptor expression-enhancing protein 4	UniProt NCBI
CEP95	Centrosomal protein of 95 kDa (Cep95) (Coiled-coil domain-containing protein 45)	UniProt NCBI
MAP7D3	MAP7 domain-containing protein 3	UniProt NCBI
ENDOD1	Endonuclease domain-containing 1 protein (EC 3.1.30.-)	UniProt NCBI
CAV3	Caveolin-3 (M-caveolin)	UniProt NCBI
PLSCR1	Phospholipid scramblase 1 (PL scramblase 1) (Ca(2+)-dependent phospholipid scramblase 1) (Erythrocyte phospholipid scramblase) (MmTRA1b)	UniProt NCBI
SPRY2	Protein sprouty homolog 2 (Spry-2)	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-381753	0.00422207068777	0.333333333333	REEP1 REEP2 REEP4	Olfactory Signaling Pathway
REAC:R-HSA-418555	0.0257605531651	0.333333333333	REEP1 REEP2 REEP4	G alpha (s) signalling events
GO:0010256	0.0317344723911	0.555555555556	REEP1 PLSCR1 REEP2 REEP4 CAV3	endomembrane system organization
HP:0009130	0.0470553832537	0.222222222222	REEP1 CAV3	Hand muscle atrophy
CORUM:422	0.0499262710315	0.111111111111	CAV3	Beta-dystroglycan-caveolin-3 complex
CORUM:6430	0.0499262710315	0.111111111111	REEP1	ATL2-SPG31 complex
CORUM:6431	0.0499262710315	0.111111111111	REEP1	ATL3-SPG31 complex
CORUM:6534	0.0499262710315	0.111111111111	REEP1	SPG31-SPG33 omplex

Protein 1	Protein 2	Score	Precision	Evidence
REEP2	CAV3	0.248	0.471	bioplex (CAV3) bioplex_WMM
SPRY2	CAV3	0.236	0.47	bioplex (CAV3) bioplex_WMM
CAV3	ENDOD1	0.169	0.426	bioplex (CAV3) bioplex_WMM
REEP2	REEP1	0.132	0.404	bioplex (REEP1) bioplex_WMM
CAV3	REEP4	0.039	0.264	bioplex (CAV3) bioplex_WMM
CAV3	MAP7D3	0.026	0.217	bioplex (CAV3) bioplex_WMM
CAV3	CEP95	0.023	0.208	bioplex (CAV3) bioplex_WMM
PLSCR1	REEP1	0.023	0.206	bioplex (REEP1) bioplex_WMM
SPRY2	PLSCR1	0.021	0.185	bioplex (SPRY2) bioplex_WMM
REEP1	REEP4	0.011	0.142	bioplex (REEP1) bioplex_WMM
REEP1	CAV3	0.009	0.108	bioplex (CAV3) bioplex_WMM
REEP2	REEP4	0.009	0.108	bioplex_WMM youn_WMM gupta_WMM WMM_only
REEP1	ENDOD1	0.009	0.091	bioplex_WMM WMM_only
SPRY2	CEP95	0.008	0.067	bioplex_WMM WMM_only
SPRY2	REEP2	0.008	0.067	bioplex_WMM WMM_only
SPRY2	REEP1	0.008	0.06	bioplex_WMM WMM_only
REEP2	CEP95	0.008	0.06	bioplex_WMM WMM_only
REEP1	CEP95	0.008	0.04	bioplex_WMM WMM_only
SPRY2	ENDOD1	0.008	0.011	bioplex_WMM WMM_only
SPRY2	REEP4	0.007	0.006	bioplex_WMM WMM_only
ENDOD1	REEP4	0.007	0.004	hein_WMM bioplex_WMM WMM_only
ENDOD1	CEP95	0.007	0.011	bioplex_WMM WMM_only
REEP2	ENDOD1	0.007	0.011	bioplex_WMM WMM_only
REEP4	CEP95	0.007	0.003	bioplex_WMM WMM_only
REEP2	PLSCR1	0.007	0.009	bioplex_WMM WMM_only
MAP7D3	CEP95	0.007	0.008	bioplex_WMM youn_WMM gupta_WMM WMM_only
SPRY2	MAP7D3	0.007	0.005	bioplex_WMM WMM_only
REEP2	MAP7D3	0.007	0.006	bioplex_WMM WMM_only
REEP1	MAP7D3	0.007	0.003	bioplex_WMM WMM_only
PLSCR1	MAP7D3	0.007	0.002	bioplex_WMM WMM_only
PLSCR1	REEP4	0.007	0.002	bioplex_WMM WMM_only
ENDOD1	MAP7D3	0.007	0.003	bioplex_WMM WMM_only
MAP7D3	REEP4	0.006	0.005	bioplex_WMM boldt boldt_WMM

Click to enlarge

Complex HuMAP2_03171 has an average edge precision of 0.112 which is ranked 6903 out of all 6965 complexes.

Genename	Complexes
REEP2	HuMAP2_00077 HuMAP2_00271 HuMAP2_03171 HuMAP2_06254
REEP1	HuMAP2_00077 HuMAP2_03171 HuMAP2_06254
REEP4	HuMAP2_03171 HuMAP2_05430
CEP95	HuMAP2_03171
MAP7D3	HuMAP2_03171
ENDOD1	HuMAP2_00271 HuMAP2_03171 HuMAP2_05499
CAV3	HuMAP2_00271 HuMAP2_03171
PLSCR1	HuMAP2_00077 HuMAP2_02998 HuMAP2_03171 HuMAP2_03415 HuMAP2_04240 HuMAP2_05251
SPRY2	HuMAP2_00077 HuMAP2_00271 HuMAP2_02998 HuMAP2_03171 HuMAP2_04240