hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03174
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MSANTD4 | Myb/SANT-like DNA-binding domain-containing protein 4 (Myb/SANT-like DNA-binding domain containing 4 with coiled-coils) | UniProt NCBI |
| RALBP1 | RalA-binding protein 1 (RalBP1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase) (Ral-interacting protein 1) | UniProt NCBI |
| REPS2 | RalBP1-associated Eps domain-containing protein 2 (Partner of RalBP1) (RalBP1-interacting protein 2) | UniProt NCBI |
| PHLDB3 | Pleckstrin homology-like domain family B member 3 | UniProt NCBI |
| SKI | Ski oncogene (Proto-oncogene c-Ski) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP437 | 0.0415833403121 | 0.4 | RALBP1 REPS2 | EGF/EGFR Signaling Pathway |
| CORUM:3198 | 0.0499494897235 | 0.2 | SKI | SKI-SMAD2 complex |
| CORUM:3199 | 0.0499494897235 | 0.2 | SKI | SKI-SMAD3 complex |
| CORUM:3200 | 0.0499494897235 | 0.2 | SKI | SMAD4-SKI complex |
| CORUM:3729 | 0.0499494897235 | 0.2 | SKI | SKI-SMAD2 complex |
| CORUM:3733 | 0.0499494897235 | 0.2 | SKI | SKI-SMAD3 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| REPS2 | RALBP1 | 0.944 | 0.856 | bioplex (RALBP1) bioplex_WMM |
| MSANTD4 | RALBP1 | 0.76 | 0.75 | bioplex (RALBP1) bioplex_WMM |
| SKI | RALBP1 | 0.358 | 0.54 | bioplex (RALBP1) bioplex_WMM |
| PHLDB3 | RALBP1 | 0.023 | 0.21 | bioplex (RALBP1) bioplex_WMM |
| MSANTD4 | REPS2 | 0.008 | 0.093 | bioplex_WMM WMM_only |
| MSANTD4 | SKI | 0.008 | 0.091 | bioplex_WMM WMM_only |
| SKI | REPS2 | 0.008 | 0.086 | bioplex_WMM WMM_only |
| PHLDB3 | MSANTD4 | 0.008 | 0.009 | bioplex_WMM WMM_only |
| PHLDB3 | REPS2 | 0.007 | 0.014 | bioplex_WMM gupta_WMM WMM_only |
| PHLDB3 | SKI | 0.007 | 0.004 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_03174 has an average edge precision of 0.265 which is ranked 5116 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MSANTD4 | HuMAP2_00838 HuMAP2_03174 HuMAP2_03366 HuMAP2_05145 HuMAP2_06069 HuMAP2_06750 |
| RALBP1 | HuMAP2_00838 HuMAP2_02993 HuMAP2_03174 HuMAP2_03366 HuMAP2_05145 HuMAP2_06069 HuMAP2_06750 |
| REPS2 | HuMAP2_00838 HuMAP2_03174 HuMAP2_03366 HuMAP2_05145 HuMAP2_06069 HuMAP2_06750 |
| PHLDB3 | HuMAP2_00838 HuMAP2_03174 |
| SKI | HuMAP2_00838 HuMAP2_03174 HuMAP2_06069 HuMAP2_06750 |