hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03191
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PML | Protein PML (Promyelocytic leukemia protein) (RING finger protein 71) (Tripartite motif-containing protein 19) | UniProt NCBI |
| ACOT8 | Acyl-coenzyme A thioesterase 8 (Acyl-CoA thioesterase 8) (EC 3.1.2.1) (EC 3.1.2.11) (EC 3.1.2.2) (EC 3.1.2.3) (EC 3.1.2.5) (Choloyl-coenzyme A thioesterase) (EC 3.1.2.27) (HIV-Nef-associated acyl-CoA thioesterase) (Peroxisomal acyl-CoA thioesterase 2) (PTE-2) (Peroxisomal acyl-coenzyme A thioester hydrolase 1) (PTE-1) (Peroxisomal long-chain acyl-CoA thioesterase 1) (Thioesterase II) (hACTE-III) (hACTEIII) (hTE) | UniProt NCBI |
| KLHL23 | Kelch-like protein 23 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00120 | 0.0499753562667 | 0.333333333333 | ACOT8 | Primary bile acid biosynthesis |
| CORUM:1055 | 0.0499776345577 | 0.333333333333 | PML | ZNF198-PML complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ACOT8 | PML | 0.678 | 0.707 | bioplex (ACOT8) bioplex_WMM |
| KLHL23 | ACOT8 | 0.059 | 0.333 | bioplex (ACOT8) bioplex_WMM |
| KLHL23 | PML | 0.007 | 0.002 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_03191 has an average edge precision of 0.347 which is ranked 4012 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PML | HuMAP2_03191 HuMAP2_03959 |
| ACOT8 | HuMAP2_03191 HuMAP2_03959 |
| KLHL23 | HuMAP2_03191 HuMAP2_03890 |