hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_03200
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MAD2L2 | Mitotic spindle assembly checkpoint protein MAD2B (Mitotic arrest deficient 2-like protein 2) (MAD2-like protein 2) (REV7 homolog) (hREV7) | UniProt NCBI |
| SHLD2 | Shieldin complex subunit 2 (Protein FAM35A) (RINN1-REV7-interacting novel NHEJ regulator 2) (Shield complex subunit 2) | UniProt NCBI |
| IFNGR1 | Interferon gamma receptor 1 (IFN-gamma receptor 1) (IFN-gamma-R1) (CDw119) (Interferon gamma receptor alpha-chain) (IFN-gamma-R-alpha) (CD antigen CD119) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7578 | 3.35600554376e-06 | 0.666666666667 | MAD2L2 SHLD2 | Shieldin complex |
| GO:0045830 | 0.0283955176165 | 0.666666666667 | MAD2L2 SHLD2 | positive regulation of isotype switching |
| MIRNA:hsa-miR-187-5p | 0.0294331428911 | 0.666666666667 | IFNGR1 SHLD2 | hsa-miR-187-5p |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MAD2L2 | SHLD2 | 0.066 | 0.349 | hein_WMM hein (MAD2L2) |
| MAD2L2 | IFNGR1 | 0.026 | 0.215 | bioplex (IFNGR1) bioplex_WMM |
Images
Click to enlarge
Complex HuMAP2_03200 has an average edge precision of 0.282 which is ranked 4853 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MAD2L2 | HuMAP2_03200 HuMAP2_04874 HuMAP2_05505 |
| SHLD2 | HuMAP2_03200 HuMAP2_04874 HuMAP2_05505 |
| IFNGR1 | HuMAP2_03200 HuMAP2_05505 |