hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03202
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| LRP4 | Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7) | UniProt NCBI |
| LRP8 | Low-density lipoprotein receptor-related protein 8 (LRP-8) (Apolipoprotein E receptor 2) | UniProt NCBI |
| LRP1B | Low-density lipoprotein receptor-related protein 1B (LRP-1B) (Low-density lipoprotein receptor-related protein-deleted in tumor) (LRP-DIT) | UniProt NCBI |
| LRPAP1 | Alpha-2-macroglobulin receptor-associated protein (Alpha-2-MRAP) (Low density lipoprotein receptor-related protein-associated protein 1) (RAP) | UniProt NCBI |
| VLDLR | Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0038025 | 0.00450823411379 | 0.4 | VLDLR LRP8 | reelin receptor activity |
| GO:0038026 | 0.0135228859698 | 0.4 | VLDLR LRP8 | reelin-mediated signaling pathway |
| GO:0030229 | 0.0270421395626 | 0.4 | VLDLR LRP8 | very-low-density lipoprotein particle receptor activity |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| LRP8 | LRPAP1 | 0.546 | 0.643 | bioplex (LRPAP1) bioplex_WMM |
| LRPAP1 | VLDLR | 0.395 | 0.555 | bioplex (LRPAP1) bioplex_WMM |
| LRPAP1 | LRP4 | 0.057 | 0.324 | bioplex (LRPAP1) bioplex_WMM |
| LRP1B | LRPAP1 | 0.056 | 0.312 | bioplex (LRPAP1) bioplex_WMM |
| LRP1B | LRP4 | 0.008 | 0.088 | bioplex_WMM WMM_only |
| LRP8 | VLDLR | 0.008 | 0.085 | bioplex_WMM WMM_only |
| LRP4 | VLDLR | 0.008 | 0.062 | bioplex_WMM WMM_only |
| LRP1B | VLDLR | 0.008 | 0.06 | bioplex_WMM WMM_only |
| LRP8 | LRP4 | 0.008 | 0.029 | bioplex_WMM WMM_only |
| LRP1B | LRP8 | 0.008 | 0.028 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_03202 has an average edge precision of 0.219 which is ranked 5881 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| LRP4 | HuMAP2_03202 HuMAP2_05261 HuMAP2_06369 |
| LRP8 | HuMAP2_00984 HuMAP2_03202 HuMAP2_06369 |
| LRP1B | HuMAP2_00364 HuMAP2_03202 |
| LRPAP1 | HuMAP2_00984 HuMAP2_03202 HuMAP2_06369 |
| VLDLR | HuMAP2_03202 HuMAP2_06369 HuMAP2_06794 |