hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03206
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MSL2 | E3 ubiquitin-protein ligase MSL2 (EC 2.3.2.-) (E3 ubiquitin-protein transferase MSL2) (Male-specific lethal 2-like 1) (MSL2-like 1) (Male-specific lethal-2 homolog) (MSL-2) (Male-specific lethal-2 homolog 1) (RING finger protein 184) | UniProt NCBI |
| CEP350 | Centrosome-associated protein 350 (Cep350) (Centrosome-associated protein of 350 kDa) | UniProt NCBI |
| PPP2R3C | Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma (Protein phosphatase subunit G5PR) (Rhabdomyosarcoma antigen MU-RMS-40.6A/6C) | UniProt NCBI |
| CEP19 | Centrosomal protein of 19 kDa (Cep19) | UniProt NCBI |
| FGFR1OP | FGFR1 oncogene partner | UniProt NCBI |
| MSL3 | Male-specific lethal 3 homolog (Male-specific lethal-3 homolog 1) (Male-specific lethal-3 protein-like 1) (MSL3-like 1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:610 | 5.0322056017e-05 | 0.333333333333 | MSL2 MSL3 | MSL complex |
| CORUM:7220 | 5.0322056017e-05 | 0.333333333333 | MSL2 MSL3 | MSL complex |
| WP:WP4536 | 0.0288305892143 | 0.333333333333 | CEP19 FGFR1OP | Genes related to primary cilium development (based on CRISPR) |
| GO:0072487 | 0.0405595771497 | 0.333333333333 | MSL2 MSL3 | MSL complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| FGFR1OP | PPP2R3C | 1.0 | 0.949 | hein_WMM bioplex (FGFR1OP) bioplex_WMM hein (FGFR1OP,PPP2R3C) gupta_WMM gupta (FGFR1OP) boldt_WMM |
| FGFR1OP | CEP350 | 1.0 | 0.949 | hein_WMM bioplex (FGFR1OP) bioplex_WMM youn_WMM hein (FGFR1OP) gupta_WMM gupta (FGFR1OP) boldt_WMM |
| FGFR1OP | CEP19 | 0.873 | 0.805 | bioplex (FGFR1OP) bioplex_WMM gupta (CEP19) |
| MSL3 | FGFR1OP | 0.485 | 0.615 | bioplex (FGFR1OP) bioplex_WMM |
| MSL2 | MSL3 | 0.095 | 0.359 | hein_WMM bioplex (MSL2) bioplex_WMM |
| PPP2R3C | CEP350 | 0.09 | 0.355 | hein_WMM bioplex_WMM hein (PPP2R3C) gupta_WMM boldt_WMM |
| MSL3 | CEP19 | 0.009 | 0.096 | bioplex_WMM WMM_only |
| MSL3 | CEP350 | 0.008 | 0.084 | bioplex_WMM WMM_only |
| MSL3 | PPP2R3C | 0.008 | 0.084 | bioplex_WMM WMM_only |
| CEP19 | CEP350 | 0.008 | 0.042 | bioplex_WMM gupta (CEP19) |
| CEP19 | PPP2R3C | 0.003 | 0.014 | bioplex_WMM gupta (CEP19) |
Images
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Complex HuMAP2_03206 has an average edge precision of 0.396 which is ranked 3371 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MSL2 | HuMAP2_00337 HuMAP2_03206 HuMAP2_03592 HuMAP2_05119 |
| CEP350 | HuMAP2_01733 HuMAP2_02720 HuMAP2_03206 HuMAP2_03521 HuMAP2_04697 |
| PPP2R3C | HuMAP2_01733 HuMAP2_02720 HuMAP2_03206 HuMAP2_03521 HuMAP2_04697 |
| CEP19 | HuMAP2_01733 HuMAP2_03206 HuMAP2_03521 |
| FGFR1OP | HuMAP2_01733 HuMAP2_02720 HuMAP2_03206 HuMAP2_03521 |
| MSL3 | HuMAP2_00337 HuMAP2_03153 HuMAP2_03206 HuMAP2_05119 HuMAP2_05861 |