hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03222
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DBNL | Drebrin-like protein (Cervical SH3P7) (Cervical mucin-associated protein) (Drebrin-F) (HPK1-interacting protein of 55 kDa) (HIP-55) (SH3 domain-containing protein 7) | UniProt NCBI |
| FGD6 | FYVE, RhoGEF and PH domain-containing protein 6 (Zinc finger FYVE domain-containing protein 24) | UniProt NCBI |
| RNF115 | E3 ubiquitin-protein ligase RNF115 (EC 2.3.2.27) (RING finger protein 115) (RING-type E3 ubiquitin transferase RNF115) (Rabring 7) (Zinc finger protein 364) | UniProt NCBI |
| NEURL4 | Neuralized-like protein 4 | UniProt NCBI |
| HERC2 | E3 ubiquitin-protein ligase HERC2 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 2) (HECT-type E3 ubiquitin transferase HERC2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6860 | 4.0241279111e-05 | 0.4 | HERC2 NEURL4 | E6AP-HERC2-MAPK6-NEURL4 complex |
| HPA:009010_23 | 0.0443141928162 | 0.6 | FGD6 HERC2 RNF115 | cervix, uterine; glandular cells[Approved,High] |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| HERC2 | NEURL4 | 0.859 | 0.796 | hein_WMM bioplex_WMM hein (HERC2) gupta_WMM boldt_WMM |
| NEURL4 | DBNL | 0.588 | 0.663 | bioplex (DBNL) bioplex_WMM gupta_WMM |
| HERC2 | DBNL | 0.245 | 0.469 | bioplex (DBNL) bioplex_WMM gupta_WMM |
| FGD6 | DBNL | 0.157 | 0.416 | bioplex (DBNL) bioplex_WMM boldt boldt_WMM |
| HERC2 | RNF115 | 0.024 | 0.214 | bioplex (HERC2) bioplex_WMM |
| FGD6 | NEURL4 | 0.008 | 0.042 | bioplex_WMM WMM_only |
| FGD6 | HERC2 | 0.008 | 0.019 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_03222 has an average edge precision of 0.374 which is ranked 3592 out of all 6965 complexes.
Related Complexes