hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03239
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MYH10 | Myosin-10 (Cellular myosin heavy chain, type B) (Myosin heavy chain 10) (Myosin heavy chain, non-muscle IIb) (Non-muscle myosin heavy chain B) (NMMHC-B) (Non-muscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) | UniProt NCBI |
| MYH9 | Myosin-9 (Cellular myosin heavy chain, type A) (Myosin heavy chain 9) (Myosin heavy chain, non-muscle IIa) (Non-muscle myosin heavy chain A) (NMMHC-A) (Non-muscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5627117 | 0.000286582912066 | 1.0 | MYH10 MYH9 | RHO GTPases Activate ROCKs |
| REAC:R-HSA-5625900 | 0.000286582912066 | 1.0 | MYH10 MYH9 | RHO GTPases activate CIT |
| REAC:R-HSA-416572 | 0.000286582912066 | 1.0 | MYH10 MYH9 | Sema4D induced cell migration and growth-cone collapse |
| REAC:R-HSA-5627123 | 0.000318425457851 | 1.0 | MYH10 MYH9 | RHO GTPases activate PAKs |
| REAC:R-HSA-400685 | 0.000424008635981 | 1.0 | MYH10 MYH9 | Sema4D in semaphorin signaling |
| REAC:R-HSA-3928663 | 0.000544675125272 | 1.0 | MYH10 MYH9 | EPHA-mediated growth cone collapse |
| GO:0097513 | 0.00135247023414 | 1.0 | MYH10 MYH9 | myosin II filament |
| KEGG:04530 | 0.00152317036077 | 1.0 | MYH10 MYH9 | Tight junction |
| KEGG:05130 | 0.00227250014745 | 1.0 | MYH10 MYH9 | Pathogenic Escherichia coli infection |
| KEGG:04810 | 0.00253730419006 | 1.0 | MYH10 MYH9 | Regulation of actin cytoskeleton |
| REAC:R-HSA-373755 | 0.00286750504412 | 1.0 | MYH10 MYH9 | Semaphorin interactions |
| REAC:R-HSA-2682334 | 0.00612550025498 | 1.0 | MYH10 MYH9 | EPH-Ephrin signaling |
| REAC:R-HSA-5625740 | 0.00716960057204 | 1.0 | MYH10 MYH9 | RHO GTPases activate PKNs |
| GO:0032982 | 0.0126230555186 | 1.0 | MYH10 MYH9 | myosin filament |
| GO:0030898 | 0.0162296428096 | 1.0 | MYH10 MYH9 | actin-dependent ATPase activity |
| HP:0008264 | 0.0497341708567 | 0.5 | MYH9 | Neutrophil inclusion bodies |
| HP:0040235 | 0.0497341708567 | 0.5 | MYH9 | Leukocyte inclusion bodies |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MYH9 | MYH10 | 0.981 | 0.897 | hein_WMM bioplex (MYH9) bioplex_WMM boldt youn_WMM hein (MYH10,MYH9) gupta_WMM boldt_WMM treiber_WMM |
Images
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Complex HuMAP2_03239 has an average edge precision of 0.897 which is ranked 582 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MYH10 | HuMAP2_02178 HuMAP2_03239 HuMAP2_03956 HuMAP2_04152 |
| MYH9 | HuMAP2_02160 HuMAP2_02178 HuMAP2_03239 HuMAP2_03956 HuMAP2_06706 |