hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_03246
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| HMGB2 | High mobility group protein B2 (High mobility group protein 2) (HMG-2) | UniProt NCBI |
| HMGB1 | High mobility group protein B1 (High mobility group protein 1) (HMG-1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:280 | 1.67592346237e-05 | 1.0 | HMGB2 HMGB1 | HMGB1-HMGB2-HSC70-ERP60-GAPDH complex |
| REAC:R-HSA-140342 | 0.000130722030065 | 1.0 | HMGB2 HMGB1 | Apoptosis induced DNA fragmentation |
| WP:WP2446 | 0.00139382676196 | 1.0 | HMGB2 HMGB1 | Retinoblastoma Gene in Cancer |
| MIRNA:hsa-miR-374c-3p | 0.00143394434463 | 1.0 | HMGB2 HMGB1 | hsa-miR-374c-3p |
| REAC:R-HSA-75153 | 0.00213680241453 | 1.0 | HMGB2 HMGB1 | Apoptotic execution phase |
| GO:0097100 | 0.00450823411379 | 1.0 | HMGB2 HMGB1 | supercoiled DNA binding |
| MIRNA:hsa-let-7a-2-3p | 0.0118707778984 | 1.0 | HMGB2 HMGB1 | hsa-let-7a-2-3p |
| GO:0051103 | 0.0126230555186 | 1.0 | HMGB2 HMGB1 | DNA ligation involved in DNA repair |
| GO:0050786 | 0.0126230555186 | 1.0 | HMGB2 HMGB1 | RAGE receptor binding |
| MIRNA:hsa-let-7g-3p | 0.0126447819481 | 1.0 | HMGB2 HMGB1 | hsa-let-7g-3p |
| GO:0006265 | 0.0162296428096 | 1.0 | HMGB2 HMGB1 | DNA topological change |
| GO:0033151 | 0.0162296428096 | 1.0 | HMGB2 HMGB1 | V(D)J recombination |
| REAC:R-HSA-109581 | 0.0237914094719 | 1.0 | HMGB2 HMGB1 | Apoptosis |
| REAC:R-HSA-5357801 | 0.0246461304377 | 1.0 | HMGB2 HMGB1 | Programmed Cell Death |
| GO:0002437 | 0.0351642260875 | 1.0 | HMGB2 HMGB1 | inflammatory response to antigenic stimulus |
| MIRNA:hsa-miR-544b | 0.0404057271957 | 1.0 | HMGB2 HMGB1 | hsa-miR-544b |
| GO:0008301 | 0.0410249304355 | 1.0 | HMGB2 HMGB1 | DNA binding, bending |
| WP:WP4479 | 0.0443803979089 | 0.5 | HMGB1 | Supression of HMGB1 mediated inflammation by THBD |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| HMGB2 | HMGB1 | 0.342 | 0.531 | bioplex_WMM gupta_WMM fraction |
Images
Click to enlarge
Complex HuMAP2_03246 has an average edge precision of 0.531 which is ranked 2327 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| HMGB2 | HuMAP2_00876 HuMAP2_03246 HuMAP2_05394 HuMAP2_05836 HuMAP2_06704 |
| HMGB1 | HuMAP2_00876 HuMAP2_03246 HuMAP2_03869 HuMAP2_06344 |