hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03255
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RABEP1 | Rab GTPase-binding effector protein 1 (Rabaptin-4) (Rabaptin-5) (Rabaptin-5alpha) (Renal carcinoma antigen NY-REN-17) | UniProt NCBI |
| RABEP2 | Rab GTPase-binding effector protein 2 (Rabaptin-5beta) | UniProt NCBI |
| RABGEF1 | Rab5 GDP/GTP exchange factor (RAP1) (Rabaptin-5-associated exchange factor for Rab5) (Rabex-5) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:50 | 1.00675659188e-05 | 0.666666666667 | RABGEF1 RABEP1 | RAB5-RABAPTIN5-RABEX5 complex |
| REAC:R-HSA-8854214 | 0.00603484671946 | 0.666666666667 | RABGEF1 RABEP1 | TBC/RABGAPs |
| REAC:R-HSA-9007101 | 0.0444303896492 | 0.666666666667 | RABGEF1 RABEP1 | Rab regulation of trafficking |
| CORUM:1090 | 0.0499776345577 | 0.333333333333 | RABEP1 | APLG1-Rababtin5 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RABEP1 | RABGEF1 | 1.0 | 0.949 | hein_WMM bioplex (RABGEF1) bioplex_WMM boldt youn_WMM hein (RABEP1) boldt_WMM |
| RABEP2 | RABGEF1 | 1.0 | 0.949 | hein_WMM bioplex (RABGEF1) bioplex_WMM boldt hein (RABEP2) boldt_WMM |
| RABEP1 | RABEP2 | 0.008 | 0.056 | bioplex_WMM boldt boldt_WMM |
Images
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Complex HuMAP2_03255 has an average edge precision of 0.651 which is ranked 1645 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RABEP1 | HuMAP2_02900 HuMAP2_03255 HuMAP2_05932 HuMAP2_06040 |
| RABEP2 | HuMAP2_03255 |
| RABGEF1 | HuMAP2_03255 HuMAP2_06040 |