hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03260
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RMI2 | RecQ-mediated genome instability protein 2 (hRMI2) (BLM-associated protein of 18 kDa) (BLAP18) | UniProt NCBI |
| RMI1 | RecQ-mediated genome instability protein 1 (BLM-associated protein of 75 kDa) (BLAP75) (FAAP75) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:03460 | 0.000171575511903 | 1.0 | RMI2 RMI1 | Fanconi anemia pathway |
| REAC:R-HSA-5693554 | 0.000544675125272 | 1.0 | RMI2 RMI1 | Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) |
| REAC:R-HSA-5693568 | 0.000831258037338 | 1.0 | RMI2 RMI1 | Resolution of D-loop Structures through Holliday Junction Intermediates |
| REAC:R-HSA-5693537 | 0.000884887588134 | 1.0 | RMI2 RMI1 | Resolution of D-Loop Structures |
| REAC:R-HSA-5685938 | 0.0010558317813 | 1.0 | RMI2 RMI1 | HDR through Single Strand Annealing (SSA) |
| REAC:R-HSA-5693616 | 0.00117817419405 | 1.0 | RMI2 RMI1 | Presynaptic phase of homologous DNA pairing and strand exchange |
| REAC:R-HSA-5693579 | 0.00137425723915 | 1.0 | RMI2 RMI1 | Homologous DNA Pairing and Strand Exchange |
| REAC:R-HSA-5685942 | 0.00348592080174 | 1.0 | RMI2 RMI1 | HDR through Homologous Recombination (HRR) |
| REAC:R-HSA-6804756 | 0.00686290657842 | 1.0 | RMI2 RMI1 | Regulation of TP53 Activity through Phosphorylation |
| REAC:R-HSA-69473 | 0.00732546145404 | 1.0 | RMI2 RMI1 | G2/M DNA damage checkpoint |
| REAC:R-HSA-5693607 | 0.00780309964082 | 1.0 | RMI2 RMI1 | Processing of DNA double-strand break ends |
| REAC:R-HSA-5693567 | 0.014052618232 | 1.0 | RMI2 RMI1 | HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) |
| REAC:R-HSA-5693538 | 0.0153849773846 | 1.0 | RMI2 RMI1 | Homology Directed Repair |
| REAC:R-HSA-5633007 | 0.0205233587202 | 1.0 | RMI2 RMI1 | Regulation of TP53 Activity |
| REAC:R-HSA-5693532 | 0.0224003929981 | 1.0 | RMI2 RMI1 | DNA Double-Strand Break Repair |
| REAC:R-HSA-69481 | 0.023229975112 | 1.0 | RMI2 RMI1 | G2/M Checkpoints |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RMI2 | RMI1 | 1.0 | 0.949 | bioplex (RMI2) bioplex_WMM |
Images
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Complex HuMAP2_03260 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RMI2 | HuMAP2_00083 HuMAP2_03260 HuMAP2_04847 HuMAP2_06528 |
| RMI1 | HuMAP2_00083 HuMAP2_03260 HuMAP2_04847 HuMAP2_06528 |