hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_03262
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| GAR1 | H/ACA ribonucleoprotein complex subunit 1 (Nucleolar protein family A member 1) (snoRNP protein GAR1) | UniProt NCBI |
| DKC1 | H/ACA ribonucleoprotein complex subunit DKC1 (EC 5.4.99.-) (CBF5 homolog) (Dyskerin) (Nopp140-associated protein of 57 kDa) (Nucleolar protein NAP57) (Nucleolar protein family A member 4) (snoRNP protein DKC1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6245 | 3.51943927099e-05 | 1.0 | GAR1 DKC1 | Telomerase holoenzyme |
| KEGG:03008 | 0.000426896214141 | 1.0 | GAR1 DKC1 | Ribosome biogenesis in eukaryotes |
| GO:0090661 | 0.00270494046827 | 1.0 | GAR1 DKC1 | box H/ACA telomerase RNP complex |
| GO:0034513 | 0.00270494046827 | 1.0 | GAR1 DKC1 | box H/ACA snoRNA binding |
| GO:0072588 | 0.00270494046827 | 1.0 | GAR1 DKC1 | box H/ACA RNP complex |
| GO:0072589 | 0.00270494046827 | 1.0 | GAR1 DKC1 | box H/ACA scaRNP complex |
| GO:0031429 | 0.00270494046827 | 1.0 | GAR1 DKC1 | box H/ACA snoRNP complex |
| REAC:R-HSA-6790901 | 0.0029663845284 | 1.0 | GAR1 DKC1 | rRNA modification in the nucleus and cytosol |
| GO:0031118 | 0.00946729163895 | 1.0 | GAR1 DKC1 | rRNA pseudouridine synthesis |
| HPA:026020_13 | 0.0109278589364 | 1.0 | GAR1 DKC1 | liver; hepatocytes[Supported,High] |
| HPA:014010_13 | 0.0110636087369 | 1.0 | GAR1 DKC1 | endometrium 2; cells in endometrial stroma[Supported,High] |
| HPA:031020_13 | 0.0117549271651 | 1.0 | GAR1 DKC1 | ovary; ovarian stroma cells[Supported,High] |
| HPA:014010_03 | 0.0165086840661 | 1.0 | GAR1 DKC1 | endometrium 2; cells in endometrial stroma[Uncertain,High] |
| HPA:031020_03 | 0.017350835606 | 1.0 | GAR1 DKC1 | ovary; ovarian stroma cells[Uncertain,High] |
| HPA:050010_13 | 0.0214945563667 | 1.0 | GAR1 DKC1 | spleen; cells in red pulp[Supported,High] |
| HPA:050020_13 | 0.0220677221908 | 1.0 | GAR1 DKC1 | spleen; cells in white pulp[Supported,High] |
| HPA:043010_13 | 0.0246385887821 | 1.0 | GAR1 DKC1 | skin 1; Langerhans[Supported,High] |
| HPA:002020_13 | 0.0269245483848 | 1.0 | GAR1 DKC1 | appendix; lymphoid tissue[Supported,High] |
| HPA:024010_13 | 0.0277809452741 | 1.0 | GAR1 DKC1 | kidney; cells in glomeruli[Supported,High] |
| HPA:032020_13 | 0.028650749551 | 1.0 | GAR1 DKC1 | pancreas; islets of Langerhans[Supported,High] |
| HPA:028010_13 | 0.028650749551 | 1.0 | GAR1 DKC1 | lymph node; germinal center cells[Supported,High] |
| REAC:R-HSA-8868773 | 0.0304096312248 | 1.0 | GAR1 DKC1 | rRNA processing in the nucleus and cytosol |
| HPA:007020_13 | 0.0315702082225 | 1.0 | GAR1 DKC1 | cerebellum; cells in granular layer[Supported,High] |
| HPA:021010_13 | 0.0324969938972 | 1.0 | GAR1 DKC1 | heart muscle; myocytes[Supported,High] |
| HPA:043040_13 | 0.0327307852202 | 1.0 | GAR1 DKC1 | skin 1; melanocytes[Supported,High] |
| REAC:R-HSA-72312 | 0.0336860615937 | 1.0 | GAR1 DKC1 | rRNA processing |
| HPA:043030_13 | 0.0339123112612 | 1.0 | GAR1 DKC1 | skin 1; keratinocytes[Supported,High] |
| GO:0001522 | 0.0351642260875 | 1.0 | GAR1 DKC1 | pseudouridine synthesis |
| HPA:027020_13 | 0.0363382104729 | 1.0 | GAR1 DKC1 | lung; pneumocytes[Supported,High] |
| HPA:028020_13 | 0.0368334458561 | 1.0 | GAR1 DKC1 | lymph node; non-germinal center cells[Supported,High] |
| HPA:035010_13 | 0.0401341771152 | 1.0 | GAR1 DKC1 | placenta; decidual cells[Supported,High] |
| HPA:009020_13 | 0.0417053553612 | 1.0 | GAR1 DKC1 | cervix, uterine; squamous epithelial cells[Supported,High] |
| HPA:036010_13 | 0.0417053553612 | 1.0 | GAR1 DKC1 | prostate; glandular cells[Supported,High] |
| HPA:014020_13 | 0.042235785137 | 1.0 | GAR1 DKC1 | endometrium 2; glandular cells[Supported,High] |
| HPA:026020_03 | 0.0427695667598 | 1.0 | GAR1 DKC1 | liver; hepatocytes[Uncertain,High] |
| HPA:022020_13 | 0.0430377145138 | 1.0 | GAR1 DKC1 | hippocampus; neuronal cells[Supported,High] |
| HPA:058010_13 | 0.044664198234 | 1.0 | GAR1 DKC1 | vagina; squamous epithelial cells[Supported,High] |
| HPA:007030_13 | 0.0454887525775 | 1.0 | GAR1 DKC1 | cerebellum; cells in molecular layer[Supported,High] |
| HPA:002020_03 | 0.0457652799488 | 1.0 | GAR1 DKC1 | appendix; lymphoid tissue[Uncertain,High] |
| HPA:056010_13 | 0.0460426452818 | 1.0 | GAR1 DKC1 | tonsil; germinal center cells[Supported,High] |
| HPA:050020_03 | 0.0474420413729 | 1.0 | GAR1 DKC1 | spleen; cells in white pulp[Uncertain,High] |
| HPA:040010_13 | 0.0474420413729 | 1.0 | GAR1 DKC1 | seminal vesicle; glandular cells[Supported,High] |
| HPA:050010_03 | 0.0477244344763 | 1.0 | GAR1 DKC1 | spleen; cells in red pulp[Uncertain,High] |
| HPA:056020_13 | 0.0480076655415 | 1.0 | GAR1 DKC1 | tonsil; non-germinal center cells[Supported,High] |
| HPA:009010_13 | 0.0491489694193 | 1.0 | GAR1 DKC1 | cervix, uterine; glandular cells[Supported,High] |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| GAR1 | DKC1 | 1.0 | 0.949 | hein_WMM bioplex (DKC1,GAR1) bioplex_WMM youn_WMM hein (GAR1) Malo fraction treiber_WMM |
Images
Click to enlarge
Complex HuMAP2_03262 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes