hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03265
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PCYT1A | Choline-phosphate cytidylyltransferase A (EC 2.7.7.15) (CCT-alpha) (CTP:phosphocholine cytidylyltransferase A) (CCT A) (CT A) (Phosphorylcholine transferase A) | UniProt NCBI |
| NMNAT1 | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 (NMN/NaMN adenylyltransferase 1) (EC 2.7.7.1) (EC 2.7.7.18) (Nicotinamide-nucleotide adenylyltransferase 1) (NMN adenylyltransferase 1) (Nicotinate-nucleotide adenylyltransferase 1) (NaMN adenylyltransferase 1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0001141 | 0.00108531561999 | 1.0 | NMNAT1 PCYT1A | Severely reduced visual acuity |
| HP:0000551 | 0.00901980766025 | 1.0 | NMNAT1 PCYT1A | Color vision defect |
| HP:0011815 | 0.0119217746565 | 1.0 | NMNAT1 PCYT1A | Cephalocele |
| HP:0002084 | 0.0119217746565 | 1.0 | NMNAT1 PCYT1A | Encephalocele |
| HP:0000563 | 0.0127833482871 | 1.0 | NMNAT1 PCYT1A | Keratoconus |
| KEGG:00440 | 0.0130349242857 | 0.5 | PCYT1A | Phosphonate and phosphinate metabolism |
| HP:0100692 | 0.0136749768118 | 1.0 | NMNAT1 PCYT1A | Increased corneal curvature |
| HP:0100689 | 0.0145966602306 | 1.0 | NMNAT1 PCYT1A | Decreased corneal thickness |
| HP:0011486 | 0.0149105669023 | 1.0 | NMNAT1 PCYT1A | Abnormality of corneal thickness |
| HP:0000540 | 0.0275703561803 | 1.0 | NMNAT1 PCYT1A | Hypermetropia |
| HP:0001103 | 0.0339052599684 | 1.0 | NMNAT1 PCYT1A | Abnormal macular morphology |
| HP:0000512 | 0.0368205846953 | 1.0 | NMNAT1 PCYT1A | Abnormal electroretinogram |
| WP:WP528 | 0.038834152205 | 0.5 | PCYT1A | Acetylcholine Synthesis |
| HP:0000662 | 0.0398561289986 | 1.0 | NMNAT1 PCYT1A | Nyctalopia |
| WP:WP2485 | 0.0443803979089 | 0.5 | NMNAT1 | NAD Biosynthesis II (from tryptophan) |
| HP:0004374 | 0.0485386539584 | 1.0 | NMNAT1 PCYT1A | Hemiplegia/hemiparesis |
| HP:0001129 | 0.0497341708567 | 0.5 | PCYT1A | Large central visual field defect |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NMNAT1 | PCYT1A | 0.027 | 0.224 | bioplex (NMNAT1) bioplex_WMM youn_WMM treiber_WMM |
Images
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Complex HuMAP2_03265 has an average edge precision of 0.224 which is ranked 5792 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PCYT1A | HuMAP2_03265 HuMAP2_05878 |
| NMNAT1 | HuMAP2_03265 HuMAP2_05940 |