hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03267
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SF3A1 | Splicing factor 3A subunit 1 (SF3a120) (Spliceosome-associated protein 114) (SAP 114) | UniProt NCBI |
| SF3A2 | Splicing factor 3A subunit 2 (SF3a66) (Spliceosome-associated protein 62) (SAP 62) | UniProt NCBI |
| SF3A3 | Splicing factor 3A subunit 3 (SF3a60) (Spliceosome-associated protein 61) (SAP 61) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1734 | 2.25356268047e-10 | 1.0 | SF3A3 SF3A1 SF3A2 | SF3A1-SF3A2-SF3A3 complex |
| GO:1903241 | 9.08185760231e-08 | 1.0 | SF3A3 SF3A1 SF3A2 | U2-type prespliceosome assembly |
| CORUM:2755 | 1.11776708952e-06 | 1.0 | SF3A3 SF3A1 SF3A2 | 17S U2 snRNP |
| GO:0000389 | 1.81637152046e-06 | 1.0 | SF3A3 SF3A1 SF3A2 | mRNA 3'-splice site recognition |
| KEGG:03040 | 1.07586932974e-05 | 1.0 | SF3A3 SF3A1 SF3A2 | Spliceosome |
| CORUM:1181 | 1.7144203448e-05 | 1.0 | SF3A3 SF3A1 SF3A2 | C complex spliceosome |
| WP:WP411 | 2.0466384774e-05 | 1.0 | SF3A3 SF3A1 SF3A2 | mRNA Processing |
| GO:0005686 | 7.41079580349e-05 | 1.0 | SF3A3 SF3A1 SF3A2 | U2 snRNP |
| CORUM:351 | 0.000100864958453 | 1.0 | SF3A3 SF3A1 SF3A2 | Spliceosome |
| GO:0006376 | 0.000265644334868 | 1.0 | SF3A3 SF3A1 SF3A2 | mRNA splice site selection |
| REAC:R-HSA-72163 | 0.000415506674825 | 1.0 | SF3A3 SF3A1 SF3A2 | mRNA Splicing - Major Pathway |
| REAC:R-HSA-72172 | 0.000474432644369 | 1.0 | SF3A3 SF3A1 SF3A2 | mRNA Splicing |
| REAC:R-HSA-72203 | 0.000960089475622 | 1.0 | SF3A3 SF3A1 SF3A2 | Processing of Capped Intron-Containing Pre-mRNA |
| GO:0071005 | 0.00178004409005 | 1.0 | SF3A3 SF3A1 SF3A2 | U2-type precatalytic spliceosome |
| GO:0071011 | 0.00189129684568 | 1.0 | SF3A3 SF3A1 SF3A2 | precatalytic spliceosome |
| GO:0000245 | 0.00200709053011 | 1.0 | SF3A3 SF3A1 SF3A2 | spliceosomal complex assembly |
| GO:0097525 | 0.00265735153444 | 1.0 | SF3A3 SF3A1 SF3A2 | spliceosomal snRNP complex |
| GO:0030532 | 0.00360649647245 | 1.0 | SF3A3 SF3A1 SF3A2 | small nuclear ribonucleoprotein complex |
| GO:0120114 | 0.00588722337212 | 1.0 | SF3A3 SF3A1 SF3A2 | Sm-like protein family complex |
| GO:0071013 | 0.00834450158358 | 1.0 | SF3A3 SF3A1 SF3A2 | catalytic step 2 spliceosome |
| GO:0005684 | 0.0110330947082 | 1.0 | SF3A3 SF3A1 SF3A2 | U2-type spliceosomal complex |
| REAC:R-HSA-8953854 | 0.0206735000409 | 1.0 | SF3A3 SF3A1 SF3A2 | Metabolism of RNA |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SF3A1 | SF3A3 | 1.0 | 0.949 | hein_WMM bioplex (SF3A1) bioplex_WMM Guru boldt youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| SF3A2 | SF3A1 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| SF3A2 | SF3A3 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM |
Images
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Complex HuMAP2_03267 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SF3A1 | HuMAP2_02806 HuMAP2_03267 HuMAP2_03568 HuMAP2_05865 HuMAP2_05951 |
| SF3A2 | HuMAP2_02806 HuMAP2_03267 HuMAP2_03568 HuMAP2_05865 |
| SF3A3 | HuMAP2_02806 HuMAP2_03267 HuMAP2_03568 HuMAP2_05865 HuMAP2_05951 |