hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03283
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RBM10 | RNA-binding protein 10 (G patch domain-containing protein 9) (RNA-binding motif protein 10) (RNA-binding protein S1-1) (S1-1) | UniProt NCBI |
| PRDX1 | Peroxiredoxin-1 (EC 1.11.1.15) (Natural killer cell-enhancing factor A) (NKEF-A) (Proliferation-associated gene protein) (PAG) (Thioredoxin peroxidase 2) (Thioredoxin-dependent peroxide reductase 2) | UniProt NCBI |
| CHERP | Calcium homeostasis endoplasmic reticulum protein (ERPROT 213-21) (SR-related CTD-associated factor 6) | UniProt NCBI |
| U2SURP | U2 snRNP-associated SURP motif-containing protein (140 kDa Ser/Arg-rich domain protein) (U2-associated protein SR140) | UniProt NCBI |
| RBM5 | RNA-binding protein 5 (Protein G15) (Putative tumor suppressor LUCA15) (RNA-binding motif protein 5) (Renal carcinoma antigen NY-REN-9) | UniProt NCBI |
| RBM17 | Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2755 | 1.11287657592e-05 | 0.5 | RBM17 CHERP U2SURP | 17S U2 snRNP |
| REAC:R-HSA-72163 | 4.76078002862e-05 | 0.666666666667 | RBM5 RBM17 CHERP U2SURP | mRNA Splicing - Major Pathway |
| REAC:R-HSA-72172 | 5.67951064007e-05 | 0.666666666667 | RBM5 RBM17 CHERP U2SURP | mRNA Splicing |
| REAC:R-HSA-72203 | 0.000144935124655 | 0.666666666667 | RBM5 RBM17 CHERP U2SURP | Processing of Capped Intron-Containing Pre-mRNA |
| KEGG:03040 | 0.000590221771159 | 0.5 | RBM17 CHERP U2SURP | Spliceosome |
| REAC:R-HSA-8953854 | 0.00833913786065 | 0.666666666667 | RBM5 RBM17 CHERP U2SURP | Metabolism of RNA |
| CORUM:3151 | 0.0249904952816 | 0.166666666667 | PRDX1 | Sulphiredoxin-peroxiredoxin complex |
| HPA:050010_23 | 0.0267002172891 | 0.5 | RBM5 RBM10 PRDX1 | spleen; cells in red pulp[Approved,High] |
| WP:WP411 | 0.0423673641592 | 0.333333333333 | RBM17 RBM5 | mRNA Processing |
| CORUM:6675 | 0.0499726005494 | 0.166666666667 | PRDX1 | PI4K2A-PRDX1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CHERP | U2SURP | 0.999 | 0.949 | hein_WMM bioplex_WMM youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| RBM17 | CHERP | 0.977 | 0.893 | hein_WMM bioplex (RBM17) bioplex_WMM youn_WMM gupta_WMM fraction boldt_WMM |
| RBM17 | U2SURP | 0.387 | 0.551 | hein_WMM bioplex (RBM17,U2SURP) bioplex_WMM youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| RBM10 | RBM17 | 0.147 | 0.408 | hein_WMM bioplex (RBM17) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| RBM5 | RBM17 | 0.119 | 0.392 | hein_WMM bioplex (RBM17) bioplex_WMM youn_WMM |
| U2SURP | PRDX1 | 0.051 | 0.301 | bioplex (U2SURP) fraction boldt_WMM |
| RBM5 | CHERP | 0.012 | 0.149 | hein_WMM bioplex_WMM youn_WMM WMM_only treiber_WMM |
| RBM10 | RBM5 | 0.01 | 0.1 | hein_WMM bioplex_WMM youn_WMM WMM_only treiber_WMM |
| RBM10 | CHERP | 0.009 | 0.111 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| RBM5 | U2SURP | 0.009 | 0.109 | hein_WMM bioplex_WMM youn_WMM WMM_only treiber_WMM |
| RBM10 | PRDX1 | 0.008 | 0.012 | bioplex_WMM boldt boldt_WMM |
| RBM10 | U2SURP | 0.007 | 0.008 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only boldt_WMM treiber_WMM |
| CHERP | PRDX1 | 0.007 | 0.01 | WMM_only |
| RBM17 | PRDX1 | 0.007 | 0.008 | bioplex (RBM17) bioplex_WMM |
| RBM5 | PRDX1 | 0.007 | 0.004 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_03283 has an average edge precision of 0.267 which is ranked 5087 out of all 6965 complexes.
Related Complexes