hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03296
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| FARSB | Phenylalanine--tRNA ligase beta subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase beta subunit) (PheRS) | UniProt NCBI |
| FARSA | Phenylalanine--tRNA ligase alpha subunit (EC 6.1.1.20) (CML33) (Phenylalanyl-tRNA synthetase alpha subunit) (PheRS) | UniProt NCBI |
| SOGA1 | Protein SOGA1 (SOGA family member 1) (Suppressor of glucose by autophagy) (Suppressor of glucose, autophagy-associated protein 1) [Cleaved into: N-terminal form; C-terminal 80 kDa form (80-kDa SOGA fragment)] | UniProt NCBI |
| SAMHD1 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (dNTPase) (EC 3.1.5.-) (Dendritic cell-derived IFNG-induced protein) (DCIP) (Monocyte protein 5) (MOP-5) (SAM domain and HD domain-containing protein 1) (hSAMHD1) | UniProt NCBI |
| CDC14A | Dual specificity protein phosphatase CDC14A (EC 3.1.3.16) (EC 3.1.3.48) (CDC14 cell division cycle 14 homolog A) | UniProt NCBI |
| SEC24A | Protein transport protein Sec24A (SEC24-related protein A) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00970 | 0.00587890830807 | 0.333333333333 | FARSB FARSA | Aminoacyl-tRNA biosynthesis |
| REAC:R-HSA-379716 | 0.0060953046166 | 0.333333333333 | FARSB FARSA | Cytosolic tRNA aminoacylation |
| GO:0009328 | 0.00676235117068 | 0.333333333333 | FARSB FARSA | phenylalanine-tRNA ligase complex |
| REAC:R-HSA-379724 | 0.0189534530409 | 0.333333333333 | FARSB FARSA | tRNA Aminoacylation |
| MIRNA:hsa-miR-503-5p | 0.0197515874976 | 0.5 | FARSA SEC24A CDC14A | hsa-miR-503-5p |
| GO:0006432 | 0.020283420769 | 0.333333333333 | FARSB FARSA | phenylalanyl-tRNA aminoacylation |
| GO:0004826 | 0.0405595771497 | 0.333333333333 | FARSB FARSA | phenylalanine-tRNA ligase activity |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| FARSA | FARSB | 0.996 | 0.928 | bioplex (FARSA) bioplex_WMM Guru youn_WMM Malo gupta_WMM fraction treiber_WMM |
| FARSA | SAMHD1 | 0.268 | 0.483 | bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM |
| FARSA | SEC24A | 0.033 | 0.254 | bioplex_WMM youn_WMM gupta_WMM fraction |
| SOGA1 | SAMHD1 | 0.03 | 0.231 | hein_WMM youn_WMM hein (SAMHD1) |
| SEC24A | FARSB | 0.027 | 0.228 | bioplex_WMM youn_WMM gupta_WMM fraction |
| FARSA | CDC14A | 0.021 | 0.187 | fraction |
| SAMHD1 | FARSB | 0.007 | 0.002 | bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| FARSA | SOGA1 | 0.007 | 0.003 | youn_WMM WMM_only boldt_WMM |
| SOGA1 | FARSB | 0.007 | 0.005 | youn_WMM WMM_only |
| SAMHD1 | SEC24A | 0.003 | 0.013 | bioplex_WMM youn_WMM fraction |
Images
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Complex HuMAP2_03296 has an average edge precision of 0.233 which is ranked 5639 out of all 6965 complexes.
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