hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03309
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| GPR156 | Probable G-protein coupled receptor 156 (G-protein coupled receptor PGR28) (GABAB-related G-protein coupled receptor) | UniProt NCBI |
| VANGL2 | Vang-like protein 2 (Loop-tail protein 1 homolog) (Strabismus 1) (Van Gogh-like protein 2) | UniProt NCBI |
| PHTF1 | Putative homeodomain transcription factor 1 | UniProt NCBI |
| VANGL1 | Vang-like protein 1 (Loop-tail protein 2 homolog) (LPP2) (Strabismus 2) (Van Gogh-like protein 1) | UniProt NCBI |
| TIFA | TRAF-interacting protein with FHA domain-containing protein A (Putative MAPK-activating protein PM14) (Putative NF-kappa-B-activating protein 20) (TRAF2-binding protein) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0008482 | 0.000139411195565 | 0.4 | VANGL1 VANGL2 | Asymmetry of spinal facet joints |
| HP:0030870 | 0.000139411195565 | 0.4 | VANGL1 VANGL2 | Abnormality of spinal facet joint |
| HP:0010305 | 0.00097535418756 | 0.4 | VANGL1 VANGL2 | Absence of the sacrum |
| HP:0008517 | 0.00361982515692 | 0.4 | VANGL1 VANGL2 | Aplasia/Hypoplasia of the sacrum |
| HP:0002475 | 0.00422256197273 | 0.4 | VANGL1 VANGL2 | Myelomeningocele |
| HP:0012032 | 0.00556671743772 | 0.4 | VANGL1 VANGL2 | Lipoma |
| WP:WP428 | 0.0186722652698 | 0.4 | VANGL1 VANGL2 | Wnt Signaling |
| HP:0001012 | 0.0244376541782 | 0.4 | VANGL1 VANGL2 | Multiple lipomas |
| HP:0012031 | 0.0325153883173 | 0.4 | VANGL1 VANGL2 | Lipomatous tumor |
| HP:0200013 | 0.0325153883173 | 0.4 | VANGL1 VANGL2 | Neoplasm of fatty tissue |
| HP:0002435 | 0.0417377803311 | 0.4 | VANGL1 VANGL2 | Meningocele |
| KEGG:04310 | 0.0451834163131 | 0.4 | VANGL1 VANGL2 | Wnt signaling pathway |
| CORUM:928 | 0.0499494897235 | 0.2 | VANGL2 | SCRIB-VANGL2 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| GPR156 | VANGL2 | 0.107 | 0.372 | bioplex (GPR156) bioplex_WMM |
| PHTF1 | GPR156 | 0.084 | 0.349 | bioplex (GPR156) bioplex_WMM |
| GPR156 | TIFA | 0.068 | 0.347 | bioplex (GPR156) bioplex_WMM |
| VANGL1 | GPR156 | 0.057 | 0.321 | bioplex (GPR156) bioplex_WMM |
| VANGL1 | VANGL2 | 0.017 | 0.175 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| PHTF1 | TIFA | 0.008 | 0.087 | bioplex_WMM WMM_only |
| VANGL2 | TIFA | 0.008 | 0.025 | bioplex_WMM WMM_only |
| VANGL1 | TIFA | 0.008 | 0.012 | bioplex_WMM WMM_only |
| PHTF1 | VANGL2 | 0.007 | 0.005 | bioplex_WMM WMM_only |
| VANGL1 | PHTF1 | 0.007 | 0.011 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_03309 has an average edge precision of 0.17 which is ranked 6521 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| GPR156 | HuMAP2_03309 HuMAP2_06761 |
| VANGL2 | HuMAP2_03309 HuMAP2_06761 |
| PHTF1 | HuMAP2_03309 HuMAP2_06761 |
| VANGL1 | HuMAP2_00382 HuMAP2_03309 HuMAP2_06761 |
| TIFA | HuMAP2_03309 HuMAP2_06761 |