hu.MAP 2.0: Complex View

Human Protein Complex Map

Complex: HuMAP2_03310

Confidence: Very High

Genename	Protein Name	Links
MTA3	Metastasis-associated protein MTA3	UniProt NCBI
MBD3L1	Methyl-CpG-binding domain protein 3-like 1 (MBD3-like protein 1)	UniProt NCBI
MTA1	Metastasis-associated protein MTA1	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:587	9.39429153233e-05	0.666666666667	MTA1 MTA3	NuRD.1 complex
WP:WP4320	0.000637825429265	0.666666666667	MTA1 MTA3	The effect of progerin on the involved genes in Hutchinson-Gilford Progeria Syndrome
REAC:R-HSA-73762	0.00722314394396	0.666666666667	MTA1 MTA3	RNA Polymerase I Transcription Initiation
REAC:R-HSA-8943724	0.0106595435179	0.666666666667	MTA1 MTA3	Regulation of PTEN gene transcription
REAC:R-HSA-427389	0.0185190091635	0.666666666667	MTA1 MTA3	ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
REAC:R-HSA-3214815	0.0285262244305	0.666666666667	MTA1 MTA3	HDACs deacetylate histones
REAC:R-HSA-5250913	0.0356968006044	0.666666666667	MTA1 MTA3	Positive epigenetic regulation of rRNA expression
REAC:R-HSA-73854	0.0392203365557	0.666666666667	MTA1 MTA3	RNA Polymerase I Promoter Clearance
REAC:R-HSA-73864	0.0399448421955	0.666666666667	MTA1 MTA3	RNA Polymerase I Transcription

Protein 1	Protein 2	Score	Precision	Evidence
MTA1	MTA3	0.997	0.93	hein_WMM bioplex_WMM youn_WMM hein (MTA1) Malo gupta_WMM fraction
MBD3L1	MTA1	0.987	0.902	bioplex (MBD3L1) bioplex_WMM
MBD3L1	MTA3	0.9	0.825	bioplex (MBD3L1) bioplex_WMM

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ComplexPrecisionDistribution

Complex HuMAP2_03310 has an average edge precision of 0.886 which is ranked 641 out of all 6965 complexes.

Related Complexes

Genename	Complexes
MTA3	HuMAP2_02937 HuMAP2_03310 HuMAP2_06754
MBD3L1	HuMAP2_01449 HuMAP2_02937 HuMAP2_03310 HuMAP2_03519 HuMAP2_04282 HuMAP2_06754
MTA1	HuMAP2_01771 HuMAP2_02937 HuMAP2_03310 HuMAP2_04282 HuMAP2_06754