hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03318
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| UAP1 | UDP-N-acetylhexosamine pyrophosphorylase (Antigen X) (AGX) (Sperm-associated antigen 2) [Includes: UDP-N-acetylgalactosamine pyrophosphorylase (EC 2.7.7.83) (AGX-1); UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23) (AGX-2)] | UniProt NCBI |
| RNPEP | Aminopeptidase B (AP-B) (EC 3.4.11.6) (Arginine aminopeptidase) (Arginyl aminopeptidase) | UniProt NCBI |
| GSS | Glutathione synthetase (GSH synthetase) (GSH-S) (EC 6.3.2.3) (Glutathione synthase) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4518 | 0.0428416541517 | 0.333333333333 | GSS | Gamma-Glutamyl Cycle for the biosynthesis and degradation of glutathione, including diseases |
| REAC:R-HSA-5579006 | 0.0498572752401 | 0.333333333333 | GSS | Defective GSS causes Glutathione synthetase deficiency (GSS deficiency) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| UAP1 | RNPEP | 0.924 | 0.843 | bioplex_WMM fraction treiber_WMM |
| UAP1 | GSS | 0.902 | 0.827 | bioplex_WMM fraction treiber_WMM |
| RNPEP | GSS | 0.0 | 0.001 | bioplex_WMM fraction treiber_WMM |
Images
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Complex HuMAP2_03318 has an average edge precision of 0.557 which is ranked 2151 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| UAP1 | HuMAP2_00452 HuMAP2_03318 HuMAP2_03858 HuMAP2_04965 HuMAP2_06360 |
| RNPEP | HuMAP2_00452 HuMAP2_03318 HuMAP2_03586 HuMAP2_03858 HuMAP2_06360 HuMAP2_06548 |
| GSS | HuMAP2_00525 HuMAP2_03318 HuMAP2_05142 |