hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03334
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| UTP4 | U3 small nucleolar RNA-associated protein 4 homolog (Cirhin) (UTP4 small subunit processome component) | UniProt NCBI |
| WDR43 | WD repeat-containing protein 43 (U3 small nucleolar RNA-associated protein 5 homolog) | UniProt NCBI |
| WDR75 | WD repeat-containing protein 75 (U3 small nucleolar RNA-associated protein 17 homolog) | UniProt NCBI |
| CNRIP1 | CB1 cannabinoid receptor-interacting protein 1 (CRIP-1) | UniProt NCBI |
| NOL11 | Nucleolar protein 11 | UniProt NCBI |
| UTP15 | U3 small nucleolar RNA-associated protein 15 homolog | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6790901 | 8.77427940368e-10 | 0.833333333333 | WDR43 WDR75 NOL11 UTP15 UTP4 | rRNA modification in the nucleus and cytosol |
| REAC:R-HSA-6791226 | 2.44317380739e-07 | 0.833333333333 | WDR43 WDR75 NOL11 UTP15 UTP4 | Major pathway of rRNA processing in the nucleolus and cytosol |
| REAC:R-HSA-8868773 | 3.20449539048e-07 | 0.833333333333 | WDR43 WDR75 NOL11 UTP15 UTP4 | rRNA processing in the nucleus and cytosol |
| REAC:R-HSA-72312 | 4.14453936466e-07 | 0.833333333333 | WDR43 WDR75 NOL11 UTP15 UTP4 | rRNA processing |
| KEGG:03008 | 4.54936912922e-07 | 0.666666666667 | WDR43 WDR75 UTP15 UTP4 | Ribosome biogenesis in eukaryotes |
| GO:0045943 | 2.18611257075e-06 | 0.666666666667 | NOL11 WDR75 UTP15 WDR43 | positive regulation of transcription by RNA polymerase I |
| GO:0006356 | 8.66795236882e-06 | 0.666666666667 | NOL11 WDR75 UTP15 WDR43 | regulation of transcription by RNA polymerase I |
| GO:0006364 | 5.93143067578e-05 | 0.833333333333 | WDR43 WDR75 NOL11 UTP15 UTP4 | rRNA processing |
| GO:0016072 | 7.66174643411e-05 | 0.833333333333 | WDR43 WDR75 NOL11 UTP15 UTP4 | rRNA metabolic process |
| REAC:R-HSA-8953854 | 0.000150175559311 | 0.833333333333 | WDR43 WDR75 NOL11 UTP15 UTP4 | Metabolism of RNA |
| GO:0090070 | 0.000152436922042 | 0.5 | WDR75 UTP15 WDR43 | positive regulation of ribosome biogenesis |
| GO:2000234 | 0.000152436922042 | 0.5 | WDR75 UTP15 WDR43 | positive regulation of rRNA processing |
| GO:0006360 | 0.000165563014397 | 0.666666666667 | NOL11 WDR75 UTP15 WDR43 | transcription by RNA polymerase I |
| GO:0042254 | 0.000277631504382 | 0.833333333333 | WDR43 WDR75 NOL11 UTP15 UTP4 | ribosome biogenesis |
| GO:2000232 | 0.00039905855691 | 0.5 | WDR75 UTP15 WDR43 | regulation of rRNA processing |
| GO:0090069 | 0.000518697707158 | 0.5 | WDR75 UTP15 WDR43 | regulation of ribosome biogenesis |
| GO:0034470 | 0.00120907776661 | 0.833333333333 | WDR43 WDR75 NOL11 UTP15 UTP4 | ncRNA processing |
| GO:0022613 | 0.00270779091032 | 0.833333333333 | WDR43 WDR75 NOL11 UTP15 UTP4 | ribonucleoprotein complex biogenesis |
| GO:0034660 | 0.00405016747169 | 0.833333333333 | WDR43 WDR75 NOL11 UTP15 UTP4 | ncRNA metabolic process |
| GO:0044452 | 0.0109703973512 | 0.666666666667 | NOL11 WDR43 UTP15 UTP4 | nucleolar part |
| MIRNA:hsa-miR-16-5p | 0.0146926265904 | 0.833333333333 | WDR43 WDR75 NOL11 UTP15 UTP4 | hsa-miR-16-5p |
| GO:0034455 | 0.020283420769 | 0.333333333333 | UTP4 NOL11 | t-UTP complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| UTP4 | NOL11 | 0.916 | 0.839 | bioplex (UTP4) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| UTP4 | WDR43 | 0.798 | 0.764 | hein_WMM bioplex (UTP4) bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| UTP4 | CNRIP1 | 0.648 | 0.686 | bioplex (CNRIP1) bioplex_WMM |
| UTP15 | UTP4 | 0.57 | 0.656 | hein_WMM bioplex (UTP4) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| UTP15 | NOL11 | 0.428 | 0.576 | bioplex_WMM youn_WMM Malo gupta_WMM fraction treiber_WMM |
| UTP4 | WDR75 | 0.398 | 0.559 | bioplex (UTP4) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| UTP15 | WDR43 | 0.015 | 0.152 | bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| WDR75 | WDR43 | 0.015 | 0.144 | bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| UTP15 | WDR75 | 0.013 | 0.151 | bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| WDR43 | NOL11 | 0.01 | 0.122 | bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| WDR75 | NOL11 | 0.009 | 0.101 | bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
Images
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Complex HuMAP2_03334 has an average edge precision of 0.432 which is ranked 3010 out of all 6965 complexes.
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