hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03348
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CALHM4 | Calcium homeostasis modulator protein 4 (Protein FAM26D) | UniProt NCBI |
| RAB11FIP5 | Rab11 family-interacting protein 5 (Rab11-FIP5) (Gamma-SNAP-associated factor 1) (Gaf-1) (Phosphoprotein pp75) (Rab11-interacting protein Rip11) | UniProt NCBI |
| RAB11FIP1 | Rab11 family-interacting protein 1 (Rab11-FIP1) (Rab-coupling protein) | UniProt NCBI |
| S100A3 | Protein S100-A3 (Protein S-100E) (S100 calcium-binding protein A3) | UniProt NCBI |
| RAB11B | Ras-related protein Rab-11B (GTP-binding protein YPT3) | UniProt NCBI |
| OR51E2 | Olfactory receptor 51E2 (HPRAJ) (Olfactory receptor OR11-16) (Prostate-specific G-protein coupled receptor) | UniProt NCBI |
| RAB25 | Ras-related protein Rab-25 (CATX-8) | UniProt NCBI |
| RAB11FIP2 | Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11) | UniProt NCBI |
| SH3BP5 | SH3 domain-binding protein 5 (SH3BP-5) (SH3 domain-binding protein that preferentially associates with BTK) | UniProt NCBI |
| RAB11A | Ras-related protein Rab-11A (Rab-11) (YL8) | UniProt NCBI |
| VSIG8 | V-set and immunoglobulin domain-containing protein 8 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04144 | 1.65773363286e-05 | 0.454545454545 | RAB11FIP5 RAB11A RAB11FIP2 RAB11FIP1 RAB11B | Endocytosis |
| CORUM:3941 | 3.35524866385e-05 | 0.181818181818 | RAB11FIP1 RAB11A | RAB11FIP1-RAB11A complex |
| CORUM:6253 | 0.000100616904936 | 0.181818181818 | RAB11FIP2 RAB11A | myosin-Vb-Rab11-FIP2-Rab11a complex |
| REAC:R-HSA-8873719 | 0.00242722946189 | 0.272727272727 | RAB25 RAB11B RAB11A | RAB geranylgeranylation |
| GO:0031489 | 0.00543043333429 | 0.272727272727 | RAB25 RAB11B RAB11A | myosin V binding |
| GO:0044060 | 0.0144271800391 | 0.272727272727 | RAB11FIP5 RAB11FIP1 OR51E2 | regulation of endocrine process |
| KEGG:04962 | 0.0171589340054 | 0.181818181818 | RAB11B RAB11A | Vasopressin-regulated water reabsorption |
| GO:0035773 | 0.0485987949639 | 0.272727272727 | RAB11FIP5 RAB11B RAB11FIP2 | insulin secretion involved in cellular response to glucose stimulus |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RAB11B | RAB11FIP2 | 1.0 | 0.949 | hein_WMM bioplex (RAB11B) bioplex_WMM gupta_WMM |
| RAB11FIP2 | RAB11A | 1.0 | 0.949 | hein_WMM bioplex (RAB11A) bioplex_WMM hein (RAB11A) |
| RAB11B | RAB11FIP5 | 0.998 | 0.936 | hein_WMM bioplex (RAB11B) bioplex_WMM gupta_WMM |
| RAB11FIP1 | RAB11A | 0.985 | 0.899 | hein_WMM bioplex (RAB11A) bioplex_WMM youn_WMM hein (RAB11A) |
| RAB11A | RAB11FIP5 | 0.958 | 0.863 | hein_WMM bioplex (RAB11A) bioplex_WMM youn_WMM hein (RAB11A) |
| RAB11FIP1 | RAB11B | 0.842 | 0.786 | hein_WMM bioplex (RAB11B,RAB11FIP1) bioplex_WMM hein (RAB11FIP1) gupta_WMM |
| RAB25 | RAB11A | 0.807 | 0.767 | bioplex (RAB11A) bioplex_WMM treiber_WMM |
| RAB11B | RAB25 | 0.703 | 0.723 | bioplex (RAB11B) bioplex_WMM |
| RAB11B | SH3BP5 | 0.4 | 0.56 | bioplex (RAB11B) bioplex_WMM |
| VSIG8 | RAB11B | 0.217 | 0.464 | bioplex (RAB11B) bioplex_WMM |
| SH3BP5 | RAB11A | 0.115 | 0.384 | bioplex (RAB11A) bioplex_WMM |
| RAB11B | RAB11A | 0.106 | 0.373 | hein_WMM hein (RAB11A) |
| VSIG8 | OR51E2 | 0.07 | 0.348 | bioplex (OR51E2) bioplex_WMM |
| CALHM4 | RAB11B | 0.055 | 0.306 | bioplex (RAB11B) bioplex_WMM |
| S100A3 | RAB11B | 0.035 | 0.263 | bioplex (RAB11B) bioplex_WMM |
| VSIG8 | S100A3 | 0.029 | 0.231 | bioplex_WMM boldt |
| OR51E2 | S100A3 | 0.023 | 0.209 | bioplex (OR51E2) bioplex_WMM |
| CALHM4 | VSIG8 | 0.02 | 0.186 | bioplex_WMM WMM_only |
| CALHM4 | S100A3 | 0.016 | 0.161 | bioplex_WMM WMM_only |
| RAB11FIP2 | SH3BP5 | 0.012 | 0.149 | bioplex_WMM WMM_only |
| RAB25 | SH3BP5 | 0.011 | 0.14 | bioplex_WMM WMM_only |
| RAB25 | RAB11FIP2 | 0.011 | 0.14 | bioplex_WMM WMM_only |
| RAB11FIP1 | RAB11FIP2 | 0.011 | 0.142 | hein_WMM bioplex_WMM boldt gupta_WMM boldt_WMM |
| RAB11FIP1 | SH3BP5 | 0.01 | 0.142 | bioplex_WMM WMM_only |
| RAB11FIP2 | RAB11FIP5 | 0.01 | 0.139 | hein_WMM bioplex_WMM gupta_WMM WMM_only boldt_WMM |
| SH3BP5 | RAB11FIP5 | 0.01 | 0.129 | bioplex_WMM WMM_only |
| RAB11FIP1 | RAB25 | 0.01 | 0.118 | bioplex_WMM WMM_only |
| RAB11FIP1 | RAB11FIP5 | 0.01 | 0.116 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only boldt_WMM |
| RAB25 | RAB11FIP5 | 0.01 | 0.097 | bioplex_WMM WMM_only |
| CALHM4 | OR51E2 | 0.009 | 0.109 | bioplex (OR51E2) bioplex_WMM |
| S100A3 | SH3BP5 | 0.008 | 0.051 | bioplex_WMM WMM_only |
| S100A3 | RAB11FIP2 | 0.008 | 0.051 | bioplex_WMM WMM_only |
| CALHM4 | RAB11FIP2 | 0.008 | 0.041 | bioplex_WMM WMM_only |
| CALHM4 | SH3BP5 | 0.008 | 0.041 | bioplex_WMM WMM_only |
| S100A3 | RAB25 | 0.008 | 0.033 | bioplex_WMM WMM_only |
| CALHM4 | RAB25 | 0.008 | 0.026 | bioplex_WMM WMM_only |
| S100A3 | RAB11FIP1 | 0.007 | 0.012 | bioplex_WMM WMM_only |
| CALHM4 | RAB11FIP1 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| S100A3 | RAB11FIP5 | 0.007 | 0.009 | bioplex_WMM WMM_only |
| CALHM4 | RAB11FIP5 | 0.007 | 0.006 | bioplex_WMM WMM_only |
| VSIG8 | SH3BP5 | 0.007 | 0.008 | bioplex_WMM WMM_only |
| VSIG8 | RAB11FIP2 | 0.007 | 0.008 | bioplex_WMM WMM_only |
| VSIG8 | RAB25 | 0.007 | 0.006 | bioplex_WMM WMM_only |
| VSIG8 | RAB11FIP1 | 0.007 | 0.006 | bioplex_WMM WMM_only |
| VSIG8 | RAB11FIP5 | 0.007 | 0.002 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_03348 has an average edge precision of 0.268 which is ranked 5059 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CALHM4 | HuMAP2_02444 HuMAP2_03348 HuMAP2_03849 |
| RAB11FIP5 | HuMAP2_03348 HuMAP2_05097 HuMAP2_06358 HuMAP2_06461 |
| RAB11FIP1 | HuMAP2_03348 HuMAP2_06089 HuMAP2_06358 HuMAP2_06461 |
| S100A3 | HuMAP2_02444 HuMAP2_03348 HuMAP2_03446 |
| RAB11B | HuMAP2_03348 HuMAP2_06358 HuMAP2_06461 |
| OR51E2 | HuMAP2_02444 HuMAP2_03348 HuMAP2_03446 HuMAP2_04166 |
| RAB25 | HuMAP2_03348 HuMAP2_06358 HuMAP2_06461 |
| RAB11FIP2 | HuMAP2_03348 HuMAP2_06358 HuMAP2_06461 |
| SH3BP5 | HuMAP2_03348 HuMAP2_06358 |
| RAB11A | HuMAP2_03348 HuMAP2_06358 HuMAP2_06461 |
| VSIG8 | HuMAP2_02444 HuMAP2_03348 HuMAP2_03446 HuMAP2_04166 |