hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03350
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ADGRL1 | Adhesion G protein-coupled receptor L1 (Calcium-independent alpha-latrotoxin receptor 1) (CIRL-1) (Latrophilin-1) (Lectomedin-2) | UniProt NCBI |
| WWOX | WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile site FRA16D oxidoreductase) (Short chain dehydrogenase/reductase family 41C member 1) | UniProt NCBI |
| HECW1 | E3 ubiquitin-protein ligase HECW1 (EC 2.3.2.26) (HECT, C2 and WW domain-containing protein 1) (HECT-type E3 ubiquitin transferase HECW1) (NEDD4-like E3 ubiquitin-protein ligase 1) (hNEDL1) | UniProt NCBI |
| FAM189B | Protein FAM189B (Protein COTE1) | UniProt NCBI |
| ST7L | Suppressor of tumorigenicity 7 protein-like (ST7-related protein) | UniProt NCBI |
| ABCD4 | ATP-binding cassette sub-family D member 4 (PMP70-related protein) (P70R) (Peroxisomal membrane protein 1-like) (PXMP1-L) (Peroxisomal membrane protein 69) (PMP69) | UniProt NCBI |
| SMO | Smoothened homolog (SMO) (Protein Gx) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| FAM189B | HECW1 | 0.606 | 0.672 | bioplex (FAM189B) bioplex_WMM |
| FAM189B | WWOX | 0.079 | 0.353 | bioplex (FAM189B,WWOX) bioplex_WMM |
| FAM189B | SMO | 0.043 | 0.269 | bioplex (FAM189B) bioplex_WMM |
| FAM189B | ST7L | 0.025 | 0.217 | bioplex (FAM189B) bioplex_WMM |
| ABCD4 | FAM189B | 0.025 | 0.213 | bioplex (FAM189B) bioplex_WMM |
| FAM189B | ADGRL1 | 0.024 | 0.215 | bioplex (FAM189B) bioplex_WMM |
| HECW1 | SMO | 0.008 | 0.091 | bioplex_WMM WMM_only |
| WWOX | HECW1 | 0.008 | 0.068 | bioplex_WMM WMM_only |
| ABCD4 | SMO | 0.008 | 0.059 | bioplex_WMM WMM_only |
| WWOX | SMO | 0.008 | 0.059 | bioplex_WMM youn_WMM WMM_only |
| ABCD4 | HECW1 | 0.008 | 0.023 | bioplex_WMM WMM_only |
| ST7L | SMO | 0.008 | 0.024 | bioplex_WMM WMM_only |
| ABCD4 | ST7L | 0.008 | 0.015 | bioplex_WMM WMM_only |
| ADGRL1 | SMO | 0.008 | 0.015 | bioplex_WMM youn_WMM WMM_only |
| ST7L | HECW1 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| ADGRL1 | HECW1 | 0.007 | 0.006 | bioplex_WMM WMM_only |
| ABCD4 | WWOX | 0.007 | 0.005 | bioplex_WMM WMM_only |
| WWOX | ST7L | 0.007 | 0.005 | bioplex_WMM WMM_only |
| WWOX | ADGRL1 | 0.007 | 0.005 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| ABCD4 | ADGRL1 | 0.007 | 0.007 | bioplex_WMM WMM_only |
| ADGRL1 | ST7L | 0.006 | 0.002 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_03350 has an average edge precision of 0.111 which is ranked 6908 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ADGRL1 | HuMAP2_03350 |
| WWOX | HuMAP2_01078 HuMAP2_01416 HuMAP2_03350 |
| HECW1 | HuMAP2_03350 HuMAP2_06123 HuMAP2_06819 |
| FAM189B | HuMAP2_01078 HuMAP2_03350 HuMAP2_06123 HuMAP2_06819 |
| ST7L | HuMAP2_03350 |
| ABCD4 | HuMAP2_00240 HuMAP2_00717 HuMAP2_03350 HuMAP2_03892 HuMAP2_03957 |
| SMO | HuMAP2_03350 HuMAP2_06123 |