hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03352
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NFIA | Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein) | UniProt NCBI |
| NFIC | Nuclear factor 1 C-type (NF1-C) (Nuclear factor 1/C) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/C) (NF-I/C) (NFI-C) (TGGCA-binding protein) | UniProt NCBI |
| NFIX | Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein) | UniProt NCBI |
| NFIB | Nuclear factor 1 B-type (NF1-B) (Nuclear factor 1/B) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/B) (NF-I/B) (NFI-B) (TGGCA-binding protein) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-73980 | 8.03058348594e-10 | 1.0 | NFIC NFIB NFIA NFIX | RNA Polymerase III Transcription Termination |
| REAC:R-HSA-749476 | 9.18415798556e-09 | 1.0 | NFIC NFIB NFIA NFIX | RNA Polymerase III Abortive And Retractive Initiation |
| REAC:R-HSA-74158 | 9.18415798556e-09 | 1.0 | NFIC NFIB NFIA NFIX | RNA Polymerase III Transcription |
| MIRNA:hsa-miR-654-5p | 0.00129044405451 | 0.75 | NFIB NFIX NFIC | hsa-miR-654-5p |
| MIRNA:hsa-miR-541-3p | 0.0013999319824 | 0.75 | NFIB NFIX NFIC | hsa-miR-541-3p |
| HP:0100729 | 0.00308958022705 | 0.75 | NFIB NFIA NFIX | Large face |
| MIRNA:hsa-miR-3714 | 0.00322772199929 | 0.75 | NFIB NFIX NFIC | hsa-miR-3714 |
| MIRNA:hsa-miR-3924 | 0.0036356588302 | 0.75 | NFIB NFIA NFIC | hsa-miR-3924 |
| MIRNA:hsa-miR-92a-2-5p | 0.00442940771454 | 0.75 | NFIB NFIX NFIC | hsa-miR-92a-2-5p |
| MIRNA:hsa-miR-6876-3p | 0.0100299120623 | 0.5 | NFIC NFIB | hsa-miR-6876-3p |
| HPA:039010_13 | 0.0101046758484 | 0.75 | NFIB NFIX NFIC | salivary gland; glandular cells[Supported,High] |
| REAC:R-HSA-74160 | 0.0102868657133 | 1.0 | NFIC NFIB NFIA NFIX | Gene expression (Transcription) |
| MIRNA:hsa-miR-626 | 0.0113006207749 | 0.5 | NFIC NFIB | hsa-miR-626 |
| MIRNA:hsa-miR-7160-3p | 0.0196380022518 | 0.5 | NFIX NFIC | hsa-miR-7160-3p |
| MIRNA:hsa-miR-124-3p | 0.0199771157926 | 1.0 | NFIC NFIB NFIA NFIX | hsa-miR-124-3p |
| HPA:006010_12 | 0.0254677066879 | 0.75 | NFIB NFIX NFIC | caudate; glial cells[Supported,Medium] |
| HPA:031020_12 | 0.0259096106078 | 0.75 | NFIB NFIX NFIC | ovary; ovarian stroma cells[Supported,Medium] |
| MIRNA:hsa-miR-4450 | 0.0302525005955 | 0.5 | NFIC NFIB | hsa-miR-4450 |
| HPA:026020_12 | 0.031444391961 | 0.75 | NFIB NFIX NFIC | liver; hepatocytes[Supported,Medium] |
| MIRNA:hsa-miR-615-5p | 0.0346755687702 | 0.5 | NFIX NFIC | hsa-miR-615-5p |
| MIRNA:hsa-miR-3918 | 0.0346755687702 | 0.5 | NFIX NFIC | hsa-miR-3918 |
| HPA:035010_12 | 0.0347513998463 | 0.75 | NFIB NFIX NFIC | placenta; decidual cells[Supported,Medium] |
| HPA:007020_12 | 0.0365805245307 | 0.75 | NFIB NFIX NFIC | cerebellum; cells in granular layer[Supported,Medium] |
| MIRNA:hsa-miR-296-5p | 0.039398521698 | 0.5 | NFIX NFIC | hsa-miR-296-5p |
| HP:0000965 | 0.0400245195282 | 0.5 | NFIA NFIX | Cutis marmorata |
| HPA:039010_03 | 0.0416307958449 | 0.75 | NFIB NFIX NFIC | salivary gland; glandular cells[Uncertain,High] |
| HP:0000463 | 0.0418131938681 | 0.75 | NFIB NFIA NFIX | Anteverted nares |
| MIRNA:hsa-miR-6801-3p | 0.0418723532423 | 0.5 | NFIX NFIB | hsa-miR-6801-3p |
| MIRNA:hsa-miR-6810-3p | 0.0418723532423 | 0.5 | NFIX NFIB | hsa-miR-6810-3p |
| HPA:041010_12 | 0.0438987109299 | 0.75 | NFIB NFIX NFIC | skeletal muscle; myocytes[Supported,Medium] |
| HP:0005288 | 0.0453169017901 | 0.75 | NFIB NFIA NFIX | Abnormality of the nares |
| MIRNA:hsa-miR-6781-5p | 0.0457234300322 | 0.5 | NFIX NFIC | hsa-miR-6781-5p |
| HPA:043020_12 | 0.0458137035926 | 0.75 | NFIB NFIX NFIC | skin 1; fibroblasts[Supported,Medium] |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NFIA | NFIB | 0.984 | 0.899 | bioplex (NFIB) bioplex_WMM youn_WMM gupta_WMM |
| NFIX | NFIB | 0.913 | 0.836 | bioplex (NFIB) bioplex_WMM |
| NFIC | NFIB | 0.5 | 0.621 | bioplex (NFIB) bioplex_WMM youn_WMM |
| NFIC | NFIA | 0.009 | 0.105 | bioplex_WMM youn_WMM WMM_only |
| NFIA | NFIX | 0.009 | 0.095 | bioplex_WMM WMM_only |
| NFIC | NFIX | 0.008 | 0.091 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_03352 has an average edge precision of 0.441 which is ranked 2929 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NFIA | HuMAP2_01554 HuMAP2_03352 |
| NFIC | HuMAP2_00375 HuMAP2_03352 |
| NFIX | HuMAP2_01554 HuMAP2_03352 |
| NFIB | HuMAP2_01554 HuMAP2_03352 |