hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03355
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| EXOC2 | Exocyst complex component 2 (Exocyst complex component Sec5) | UniProt NCBI |
| EXOC3 | Exocyst complex component 3 (Exocyst complex component Sec6) | UniProt NCBI |
| TRIP11 | Thyroid receptor-interacting protein 11 (TR-interacting protein 11) (TRIP-11) (Clonal evolution-related gene on chromosome 14 protein) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:89 | 9.39429153233e-05 | 0.666666666667 | EXOC2 EXOC3 | Exocyst Sec6/8 complex |
| CORUM:6167 | 9.39429153233e-05 | 0.666666666667 | EXOC2 EXOC3 | Exocyst complex |
| REAC:R-HSA-5617833 | 0.000513949964862 | 1.0 | EXOC2 EXOC3 TRIP11 | Cilium Assembly |
| REAC:R-HSA-5620916 | 0.00114404160216 | 0.666666666667 | EXOC2 EXOC3 | VxPx cargo-targeting to cilium |
| REAC:R-HSA-1852241 | 0.00160990717739 | 1.0 | EXOC2 EXOC3 TRIP11 | Organelle biogenesis and maintenance |
| REAC:R-HSA-264876 | 0.00184610965854 | 0.666666666667 | EXOC2 EXOC3 | Insulin processing |
| REAC:R-HSA-5620920 | 0.00722314394396 | 0.666666666667 | EXOC2 EXOC3 | Cargo trafficking to the periciliary membrane |
| REAC:R-HSA-199991 | 0.0146202486223 | 1.0 | EXOC2 EXOC3 TRIP11 | Membrane Trafficking |
| REAC:R-HSA-1445148 | 0.015207050821 | 0.666666666667 | EXOC2 EXOC3 | Translocation of SLC2A4 (GLUT4) to the plasma membrane |
| REAC:R-HSA-2980736 | 0.015660289467 | 0.666666666667 | EXOC2 EXOC3 | Peptide hormone metabolism |
| REAC:R-HSA-5653656 | 0.0171761243356 | 1.0 | EXOC2 EXOC3 TRIP11 | Vesicle-mediated transport |
| WP:WP4352 | 0.0212517549636 | 0.666666666667 | EXOC2 EXOC3 | Ciliary landscape |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TRIP11 | EXOC3 | 0.994 | 0.921 | bioplex (EXOC3) bioplex_WMM boldt (EXOC3) gupta_WMM boldt_WMM |
| EXOC2 | EXOC3 | 0.99 | 0.909 | bioplex (EXOC3) bioplex_WMM boldt (EXOC2,EXOC3) Malo fraction boldt_WMM treiber_WMM |
| TRIP11 | EXOC2 | 0.007 | 0.007 | bioplex_WMM boldt boldt_WMM |
Images
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Complex HuMAP2_03355 has an average edge precision of 0.612 which is ranked 1878 out of all 6965 complexes.
Related Complexes