hu.MAP 2.0: Complex View

Human Protein Complex Map

Complex: HuMAP2_03373

Confidence: Medium High

Genename	Protein Name	Links
AKTIP	AKT-interacting protein (Ft1) (Fused toes protein homolog)	UniProt NCBI
HOOK1	Protein Hook homolog 1 (h-hook1) (hHK1)	UniProt NCBI
HOOK2	Protein Hook homolog 2 (h-hook2) (hHK2)	UniProt NCBI
NAB1	NGFI-A-binding protein 1 (EGR-1-binding protein 1) (Transcriptional regulatory protein p54)	UniProt NCBI
FAM160A1	Protein FAM160A1	UniProt NCBI
HOOK3	Protein Hook homolog 3 (h-hook3) (hHK3)	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:6109	2.26981451009e-12	0.666666666667	HOOK3 HOOK1 HOOK2 AKTIP	FHF complex
GO:0070695	1.82947049513e-09	0.666666666667	HOOK3 HOOK1 HOOK2 AKTIP	FHF complex
GO:0030897	1.80981361376e-07	0.666666666667	HOOK3 HOOK1 HOOK2 AKTIP	HOPS complex
GO:0045022	2.40824494048e-05	0.666666666667	HOOK3 HOOK1 HOOK2 AKTIP	early endosome to late endosome transport
GO:0098927	2.99853000209e-05	0.666666666667	HOOK3 HOOK1 HOOK2 AKTIP	vesicle-mediated transport between endosomal compartments
GO:0008333	4.07918542432e-05	0.666666666667	HOOK3 HOOK1 HOOK2 AKTIP	endosome to lysosome transport
GO:0080171	5.42823133593e-05	0.666666666667	HOOK3 HOOK1 HOOK2 AKTIP	lytic vacuole organization
GO:0007040	5.42823133593e-05	0.666666666667	HOOK3 HOOK1 HOOK2 AKTIP	lysosome organization
GO:0099023	0.000133653758006	0.666666666667	HOOK3 HOOK1 HOOK2 AKTIP	vesicle tethering complex
GO:0007032	0.000333147323349	0.666666666667	HOOK3 HOOK1 HOOK2 AKTIP	endosome organization
GO:0007041	0.00084563217517	0.666666666667	HOOK3 HOOK1 HOOK2 AKTIP	lysosomal transport
GO:0007034	0.00224645012257	0.666666666667	HOOK3 HOOK1 HOOK2 AKTIP	vacuolar transport
GO:0007033	0.00422920591485	0.666666666667	HOOK3 HOOK1 HOOK2 AKTIP	vacuole organization
GO:0051959	0.00592798461195	0.5	HOOK1 HOOK2 HOOK3	dynein light intermediate chain binding
GO:0016482	0.00602077161694	0.666666666667	HOOK3 HOOK1 HOOK2 AKTIP	cytosolic transport
GO:0031122	0.0239073169747	0.5	HOOK1 HOOK2 HOOK3	cytoplasmic microtubule organization
CORUM:6116	0.0499726005494	0.166666666667	HOOK1	Hook1-Vps16 complex
CORUM:6117	0.0499726005494	0.166666666667	HOOK1	Hook1-Vps18 complex
CORUM:6118	0.0499726005494	0.166666666667	HOOK1	Hook1-Vps39 complex
CORUM:6119	0.0499726005494	0.166666666667	HOOK1	Hook1-Vps41 complex
CORUM:6120	0.0499726005494	0.166666666667	HOOK2	Hook2-Vps16 complex
CORUM:6121	0.0499726005494	0.166666666667	HOOK2	Hook2-Vps41 complex
CORUM:6122	0.0499726005494	0.166666666667	HOOK3	Hook3-Vps16 complex
CORUM:6123	0.0499726005494	0.166666666667	HOOK3	Hook3-Vps41 complex
CORUM:6124	0.0499726005494	0.166666666667	AKTIP	FTS-Vps16 complex
CORUM:6125	0.0499726005494	0.166666666667	AKTIP	FTS-Vps18 complex
CORUM:6126	0.0499726005494	0.166666666667	AKTIP	FTS-Vps41 complex
CORUM:7441	0.0499726005494	0.166666666667	HOOK1	HOOK1-SHP2 complex

Edges

Protein 1	Protein 2	Score	Precision	Evidence
AKTIP	FAM160A1	1.0	0.949	bioplex (AKTIP) bioplex_WMM youn_WMM
AKTIP	HOOK3	0.999	0.949	bioplex (AKTIP,HOOK3) bioplex_WMM youn_WMM gupta_WMM
AKTIP	HOOK1	0.989	0.904	bioplex (AKTIP) bioplex_WMM youn_WMM
AKTIP	HOOK2	0.786	0.758	bioplex (AKTIP) bioplex_WMM
AKTIP	NAB1	0.344	0.533	bioplex (AKTIP) bioplex_WMM
HOOK3	FAM160A1	0.241	0.468	bioplex (HOOK3) bioplex_WMM youn_WMM
HOOK1	HOOK3	0.025	0.215	bioplex (HOOK3) bioplex_WMM youn_WMM gupta_WMM fraction
HOOK1	FAM160A1	0.01	0.112	bioplex_WMM youn_WMM WMM_only
NAB1	FAM160A1	0.009	0.092	bioplex_WMM WMM_only
NAB1	HOOK3	0.008	0.082	bioplex_WMM WMM_only
FAM160A1	HOOK2	0.008	0.077	bioplex_WMM WMM_only
NAB1	HOOK2	0.008	0.06	bioplex_WMM WMM_only
HOOK3	HOOK2	0.008	0.06	bioplex_WMM WMM_only
NAB1	HOOK1	0.008	0.027	bioplex_WMM WMM_only
HOOK1	HOOK2	0.008	0.011	bioplex_WMM WMM_only

Images

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Complex HuMAP2_03373 has an average edge precision of 0.353 which is ranked 3885 out of all 6965 complexes.

Related Complexes

Genename	Complexes
AKTIP	HuMAP2_00058 HuMAP2_03373 HuMAP2_03893 HuMAP2_05370
HOOK1	HuMAP2_00058 HuMAP2_03373 HuMAP2_03893 HuMAP2_05370 HuMAP2_06146
HOOK2	HuMAP2_03373 HuMAP2_03773 HuMAP2_03893 HuMAP2_04886 HuMAP2_05370
NAB1	HuMAP2_00058 HuMAP2_01143 HuMAP2_03373 HuMAP2_05370
FAM160A1	HuMAP2_00058 HuMAP2_03373 HuMAP2_03893 HuMAP2_05370
HOOK3	HuMAP2_00058 HuMAP2_03373 HuMAP2_03893 HuMAP2_05370

hu.MAP 2.0: Complex View

Search for a protein

Complex: HuMAP2_03373