hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03384
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RIDA | 2-iminobutanoate/2-iminopropanoate deaminase (EC 3.5.99.10) (14.5 kDa translational inhibitor protein) (hp14.5) (p14.5) (Heat-responsive protein 12) (Reactive intermediate imine deaminase A homolog) (Translation inhibitor L-PSP ribonuclease) (UK114 antigen homolog) | UniProt NCBI |
| NEDD8 | NEDD8 (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8) (NEDD-8) (Ubiquitin-like protein Nedd8) | UniProt NCBI |
| GCK | Glucokinase (EC 2.7.1.2) (Hexokinase type IV) (HK IV) (Hexokinase-4) (HK4) (Hexokinase-D) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00524 | 0.0166696437743 | 0.333333333333 | GCK | Neomycin, kanamycin and gentamicin biosynthesis |
| REAC:R-HSA-5619073 | 0.0498572752401 | 0.333333333333 | GCK | Defective GCK causes maturity-onset diabetes of the young 2 (MODY2) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NEDD8 | RIDA | 0.135 | 0.407 | bioplex_WMM fraction |
| NEDD8 | GCK | 0.053 | 0.3 | fraction |
| GCK | RIDA | 0.006 | 0.004 | fraction |
Images
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Complex HuMAP2_03384 has an average edge precision of 0.237 which is ranked 5584 out of all 6965 complexes.
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