hu.MAP 2.0: Complex View

Human Protein Complex Map

Complex: HuMAP2_03388

Confidence: Very High

Genename	Protein Name	Links
WDR7	WD repeat-containing protein 7 (Rabconnectin-3 beta) (TGF-beta resistance-associated protein TRAG)	UniProt NCBI
DMXL2	DmX-like protein 2 (Rabconnectin-3)	UniProt NCBI
DMXL1	DmX-like protein 1 (X-like 1 protein)	UniProt NCBI
ROGDI	Protein rogdi homolog	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0043291	3.63274304092e-07	0.75	DMXL2 DMXL1 ROGDI	RAVE complex
GO:0007035	0.000351729129078	0.75	DMXL2 DMXL1 ROGDI	vacuolar acidification
GO:0051452	0.00386509246613	0.75	DMXL2 DMXL1 ROGDI	intracellular pH reduction
GO:0045851	0.00416219722544	0.75	DMXL2 DMXL1 ROGDI	pH reduction
GO:0051453	0.017346559408	0.75	DMXL2 DMXL1 ROGDI	regulation of intracellular pH
GO:0030641	0.0189701239271	0.75	DMXL2 DMXL1 ROGDI	regulation of cellular pH
GO:0006885	0.0215903857674	0.75	DMXL2 DMXL1 ROGDI	regulation of pH
GO:0030004	0.0308728000114	0.75	DMXL2 DMXL1 ROGDI	cellular monovalent inorganic cation homeostasis

Protein 1	Protein 2	Score	Precision	Evidence
ROGDI	DMXL1	1.0	0.949	bioplex (ROGDI) bioplex_WMM
ROGDI	WDR7	0.999	0.947	bioplex (ROGDI) bioplex_WMM
DMXL2	ROGDI	0.968	0.88	bioplex (ROGDI) bioplex_WMM
WDR7	DMXL1	0.012	0.15	bioplex_WMM WMM_only
DMXL2	WDR7	0.008	0.081	bioplex_WMM WMM_only
DMXL2	DMXL1	0.008	0.075	bioplex_WMM WMM_only

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ComplexPrecisionDistribution

Complex HuMAP2_03388 has an average edge precision of 0.514 which is ranked 2422 out of all 6965 complexes.

Related Complexes

Genename	Complexes
WDR7	HuMAP2_01834 HuMAP2_03388
DMXL2	HuMAP2_01148 HuMAP2_01834 HuMAP2_03388
DMXL1	HuMAP2_01834 HuMAP2_03388
ROGDI	HuMAP2_01148 HuMAP2_01834 HuMAP2_03388