hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_03390
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| FRK | Tyrosine-protein kinase FRK (EC 2.7.10.2) (FYN-related kinase) (Nuclear tyrosine protein kinase RAK) (Protein-tyrosine kinase 5) | UniProt NCBI |
| EIF2S3 | Eukaryotic translation initiation factor 2 subunit 3 (Eukaryotic translation initiation factor 2 subunit gamma X) (eIF-2-gamma X) (eIF-2gX) | UniProt NCBI |
| CSK | Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL) | UniProt NCBI |
| PCBP1 | Poly(rC)-binding protein 1 (Alpha-CP1) (Heterogeneous nuclear ribonucleoprotein E1) (hnRNP E1) (Nucleic acid-binding protein SUB2.3) | UniProt NCBI |
| MET | Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:05120 | 0.00779513141567 | 0.4 | CSK MET | Epithelial cell signaling in Helicobacter pylori infection |
| CORUM:2541 | 0.0499494897235 | 0.2 | MET | HGF-Met complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| FRK | PCBP1 | 1.0 | 0.949 | bioplex (PCBP1) bioplex_WMM |
| PCBP1 | MET | 0.671 | 0.704 | bioplex (PCBP1) bioplex_WMM |
| CSK | FRK | 0.059 | 0.333 | bioplex (CSK) bioplex_WMM |
| EIF2S3 | PCBP1 | 0.042 | 0.27 | bioplex (PCBP1) bioplex_WMM gupta_WMM fraction treiber_WMM |
| FRK | MET | 0.009 | 0.097 | bioplex_WMM WMM_only |
| EIF2S3 | CSK | 0.007 | 0.005 | youn_WMM gupta_WMM WMM_only |
| CSK | PCBP1 | 0.007 | 0.006 | bioplex (CSK) gupta_WMM treiber_WMM |
Images
Click to enlarge
Complex HuMAP2_03390 has an average edge precision of 0.338 which is ranked 4148 out of all 6965 complexes.
Related Complexes